Member, Human Biology Division; Member, Clinical Research Division
Professor, Department of Neurology, University of Washington
Dr. Tapscott obtained an M.D. and Ph.D. degree from the University of Pennsylvania, where he also completed medical internship and neurology residency. He completed postdoctoral studies with Dr. Harold Weintraub at Fred Hutchinson Cancer Research Center in Seattle, where he is currently a Member in the Divisions of Human Biology and Clinical Research, and a Professor of Neurology at the University of Washington. His research focuses on the regulation of gene expression during cell differentiation using myogenesis and neurogenesis as model systems. In addition, his lab has active programs in the role of triplet and macrosatellite repeats in the genome, epigenetic regulation in development and in cancer, and cellular and genetic therapies for muscular dystrophies. Dr. Tapscott serves on the scientific advisory boards of the American Brain Tumor Association and the Max Planck Institute Bad Nauheim in Germany. He is also an Advisory Council Member at the National Institute of Arthritis, Musculoskeletal and Skin Diseases and on the Editorial Boards of Developmental Cell and Muscle & Nerve.
Sean has a B.S. in Aquatic and Fishery Sciences from the University of Washington and currently assists with projects in the Tapscott Lab and helps with day to day operations.
Amy received a B.A. in Biology from Reed College and a Ph.D. in Cell and Molecular Biology from the University of Pennsylvania, where she studied genetic and epigenetic control of hematopoiesis with Dr. Gerd Blobel. She joined the Tapscott Lab in 2013 as a postdoctoral research fellow to investigate DUX4 regulation and function, and to identify therapeutic targets for facioscapulohumeral muscular dystrophy (FSHD). Amy continues to study DUX4 and FSHD biology as a staff scientist, and is also responsible for day-to-day management of the Tapscott Lab.
Jessica received her B.A. in Biochemistry at the University of Washington in 2017. She assists with various projects performing standard and investigative bench-level experiments. She is working toward graduate/medical school admissions in the next few years. After work hours, she enjoys climbing and playing outside.
Rebecca received a B.A. in Biology from Amherst College and has been a part of UW’s Medical Scientist Training Program since 2012. She was a graduate student in the Molecular and Cellular Biology Program and recently completed her Ph.D. in the Tapscott Lab studying DUX4 regulation and epigenetics in FSHD. She will return to her medical training in mid-2019.
Amy received her B.A. in Biology and Anthropology from Bowdoin College and worked at Fred Hutch for 2 years before joining UW's Molecular and Cellular Biology Ph.D. program in 2017. She is most interested in the regulation of DUX4 and the mechanism by which DUX4 modulates cells' immune responses. When not in lab she loves to bike, kayak, and hammock her way throughout Seattle.