Strong Lab Tour

The Strong Lab uses the tools of structural molecular biology (including biophysical methods such as x-ray crystallography and surface plasmon resonance (Biacore) biomolecular interaction analysis), combined with our recently developed Daedalus protein expression platform, to study receptor/ligand and antibody/antigen interactions.



The Fred Hutch Structural Molecular Biology Core Facility, shared and jointly administered by two laboratories at the Hutch (Strong and Stoddard), comprises an x-ray laboratory with image-plate and CCD area detectors and a crystallization laboratory with microscopes and incubators for crystallization experiments.

Fred Hutch also owns a share of the 5.0.1 (monochromatic protein crystallography) and 5.0.2 (multiple wavelength anomalous diffraction and monochromatic protein crystallography) beamlines at the Advanced Light Source (ALS; Berkeley, CA) providing approximately 10 days per year to the Core Facility. Access to this type of facility is necessary for conducting protein structure determinations by x-ray crystallography; access to synchrotron light sources are necessary for collecting the highest-quality diffraction data or data from weakly-diffracting crystals.