Stoddard Lab

2017-2018 FHCRC Structural Biology and Molecular Biophysics Journal Club Meetings (A3M-015)

DATE                                PRESENTER

September 28                Ian Haydon (Baker Lab, Univ. of Washington)

"TIM Barrel engineering"


October  12                    Kevin Forsberg (Malik Lab) 

Cas9 Inhibitor screening and identification"


October 26                      Elizabeth Kellogg (U.C. Berkeley)

Using cryo-EM to reveal the atomic structure of microtubule-bound tau""


November 2                    Abbie Lambert (Stoddard Lab)

"Structural insights into a secretory abundant heat-soluble protein from an anhydrobiotic tardigrade,                              Ramazzottius varieornatus" (Fukuda et al. 2017 FEBS Letters 591 (16): 2458 - 2469.


November 16                  Jean Campbell / Rob Pierce (FHCRC Program in Immunology; Clinical Research Division)

"Nanobody development and applications"


December 7                    Jazmine Hallinan (Stoddard Lab)

"Crystal structure of an LSD-bound human serotonin receptor" (Wacker et al. (2017) Cell 168: 377-389).


December 21                  Cancelled--last minute holiday shopping instead!


January 4                        Peter Rupert 

"LIN28 zinc knuckle domain is required and sufficient to induce let-7 oligouridylation" (Wang et al. 2017 Cell Reports 18: 2664 - 2675).


January 18                      Mesfin Gewe (Olsen Lab)

"Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques" (Xu et al. (2017) Science 358: 85 - 90).


February 1                      Phil Bradley (Computational Biology Program)

" A self-assembled nanoscale robotic arm controlled by electric fields" (Kopperger et al. (2018) Science 359: 296-301.


February 15                    Connor Weidle (Stamatatos/Pancera Lab)

" Three-dimensional electron crystallogrqaphy of protein microcrystals" (Shi et al. (2013) eLife  2: e01345 DOI: 10.7554/eLife.01345


March 1                           Amanda Qu (Stoddard Lab) 

" Identification and experimental characterization of an extremophilic brine pool alcohol dehydrogenase from single amplified genomes." (Grötzinger et al. (2018) ACS Chemical Biology, 13(1), 161–170.


March 22                         Lindsey Doyle (Stoddard Lab)

"Method to generate highly stable D-amino acid analogs of bioactive helical peptides using a mirror image of the entire PDB" (2018) Garton et al. PNAS 115 (7): 1505 - 1510).


March 29                         Tyler Liban (Stamatatos/Pancera Lab)

"Yeast surface display platform for rapid discovery of conformationally selective nanobodies" McMahon et al. (2018) Nature Structural and Molecular Biology 25: 289 - 296.


April 12                           Rachel Werther (Stoddard Lab)

"Structural basis for shelterin bridge assembly" Kim et al. (2017) Molecular Cell 68: 698 - 714.


April 26                           Chance Brock (Strong Lab)

Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor”  Tao Che et al. (2018) Cell 17255-67.


May 17                            Roland Strong


May 24                            Barry Stoddard


June 21                           Betty Shen (Stoddard Lab)