Publications

For a complete list of publications, see Julie Overbaugh’s NCBI bibliography.

Select Recent Publications

Sharma A, McLaughlin RN, Basom RS, OhAinle M, Kikawa C, Yount JS, Emerman M, Overbugh J. Macaque IFITMs limit replication of SHIVs derived from circulating HIV-1 in an Envelope-dependent manner. PLoS Pathogens, in press, 2019

Simonich CA,, Doepker LN, Ralph D,  Williams JA, Dhar A, Yaffe Z, Gentles L, Small CT, Oliver B, Vigdorovich V, Prasad VM, Nduati R, Sather DN, Lee KK, Matsen FA, Overbaugh J.  Rapid development of an infant-derived HIV-1 broadly neutralizing antibody lineage.  Nature Communication, 10: article 2190, 2019.

Williams KL, Stumpf M, Naiman N, Ding S, Garrett M, Gobillot T, Vezina D, Dusenbury K, Ramadoss NS, Basom R, Kim PS, Finzi A, Overbaugh J. Identification of HIV gp41-specific antibodies that mediate killing of infected cells. PLoS Pathog. 2019 Feb 19;15(2):e1007572.

Dingens AS, Arenz D, Weight H, Overbaugh J, Bloom JD. An antigenic atlas of HIV-1 escape from broadly neutralizing antibodies. Immunity. 2019 Feb 19;50(2):520-532.e3.

Ohainle M, Pendergast L, Vermeire J, Roesch F, Humes D, Basom R, Delrow J, Overbaugh J, Emerman M. A Virus-Packageable CRISPR Screen Identities Host Factors Mediating Interferon Inhibition of HIV. eLife, 7:e39823, 2018.

McClelland RS, Lingappa JR, Srinivasan S, Kinuthia J, John-Stewart GC, Jaoko W, Richardson BA, Yuhas K, Fiedler TL, Mandaliya KN, Munch MM, Mugo NR, Cohen CR, Baeten JM, Celum C, Overbaugh J, Fredricks DN. Evaluation of the association between the concentrations of key vaginal bacteria and the increased risk of HIV acquisition in African women from five cohorts: a nested case-control study. Lancet Infect Dis, 18(5):554-564, 2018.

Williams KL, Wang B, Arenz D, Williams JA, Dingens AS, Cortez V, Simonich CA, Lehman DA, Rainwater S, Lee KK, Overbaugh J. Superinfection drives HIV neutralizing antibody responses from several B cell lineages that contribute to a polyclonal response. Cell Reports, 23(3):682-691, 2018.

Dingens AS, Haddox HK, Overbaugh J, Bloom JD. Comprehensive Mapping of HIV-1 Escape from Broadly Neutralizing Antibody. Cell Host & Microbe, 21(6): 777-787, 2017.

Ronen K, Dingens AS, Graham SM, Jaoko W, Mandaliya K, McClelland RS, Overbaugh J. Comprehensive Characterization of Humoral Correlates of Human Immunodeficiency Virus 1 Superinfection Acquisition in High-Risk Kenyan Women. EBioMedicine, 18, 216-244, 2017.

Boyd DF, Sharma A, Humes D, Cheng-Mayer C and Overbaugh J. Adapting SHIVs in vivo selects for Envelope-mediated Interferon- resistance. PLos Pathogens 12(7): e1005727, 2016.

Simonich CA, Williams KL, Verkerke HP, Williams JA, Nduati R, Lee KK and Overbaugh J. HIV-1 neutralizing antibodies with limited hypermuation from an infant. Cell, 166:77-87, 2016.

Milligan C, Omenda MM, Chohan V, Odem-Davis K, Richardson BA, Nduati R and Overbaugh J. Maternal neutralization-resistant virus variants do not predict infant HIV infection risk. mBio 7, 2016.

McClelland RS, Richardson BA, Cherutich P, Mandaliya K, John-Stewart G, Miregwa B, Odem-Davis K, Jaoko W, Kimanga D and Overbaugh J. A 15-year study of the impact of community antiretroviral therapy coverage on HIV incidence in Kenyan female sex workers: A fifteen-year prospective study. AIDS, 29: 2279-2286, 2015. AIDS Res Hum Retroviruses. 2015 Mar;31(3):288-92.

Williams KL, Cortez V, Dingens AS, Gach JS, Rainwater S, Weis JF, Chen X, Spearman P, Forthal DN and Overbaugh J. HIV-specific CD4-induced antibodies mediate broad and potent antibody-dependent cellular cytotoxicity activity and are commonly detected in plasma from HIV-infected humans. EBioMedicine 2, 1464-1477, 2015.

Cortez V, Wang B, Dingens A, Chen MM, Ronen K, Georgiev IS, McClelland RS, Overbaugh J. The broad neutralizing antibody responses after HIV-1 superinfection are not dominated by antibodies directed to epitopes common in single infection. PLoS Pathogens, 11(7): e1004973, 2015.

Myerson NR, Sharma A, Wilkerson GK, Overbaugh J, Sawyer SL. Identification of a nonhuman primate CD4 receptor broadly compatible with primary HIV-1 isolates. J. Virol. 89:8611-8622, 2015.

Milligan C, Richardson BA, John-Stewart G, Nduati R, Overbaugh J. Passively acquired antibody–dependent cellular cytotoxicity (ADCC) activity in HIV-infected infants is associated with reduced mortality. Cell Host& Microbe 17: 500-506, 2015.

Boyd DF, Peterson D, Haggarty BS, Jordan APO, Hogan MJ, Goo L, Hoxie JA, Overbaugh J. Mutations in HIV-1 envelope that enhance entry with the macaque CD4 receptor alter antibody recognition by disrupting quaternary interactions within the trimer. Journal of Virology. 15;89(2):894-907, 2015.

Ronen K, Richardson BA, Graham SM, Jaoko W, Mandaliya K, McClelland RS, Richardson BA, Overbaugh J. HIV-1 superinfection is associated with an accelerated viral load increase but has a limited impact on disease progression. AIDS 28:2281-2286, 2014.

Goo L, Chohan V, Nduati R, Overbaugh J. Early development of broad neutralizing antibodies in HIV-1 infected infants. Nat Med., 20, 655-658, 2014.

Select Recent Reviews and Commentaries

Clynes M, Corbett A, Overbaugh J. Why we need good mentoring. Nature Reviews Cancer, in press, 2019.

Overbaugh J. Defining the barriers to women publishing in high-impact journals. J Virol, 92(7), 2018.

Overbaugh J.  Gender Bias: track revisions and appeals.  Nature: 543: 40, 2017.

Ronen K, Sharma A, Overbaugh J. HIV transmission biology: translation for HIV prevention. AIDS 29: 2219-2227, 2015

Overbaugh, J. Mother-Infant HIV Transmission: Do maternal HIV-specific antibodies protect the infant? PLoS Pathogens 10:e1004283, 2014.

Overbaugh J. 24/7 isn’t the only way: A healthy work-life balance can enhance research. Nature 477(7362): 27-28, 2011.