Publications

Researcher working with tissue samples in a lab

2015-2018

McCune JS, Storer B, Thomas S, McKiernan J, Gupta R, Sandmaier BM.(2018) Inosine Monophosphate Dehydrogenase Pharmacogenetics in Hematopoietic Cell Transplantation Patients. Biol Blood Marrow Transplant. April 12. PMID: 29656138. 

Yuan Z, Baker K, Redman MW, Wang L, Adams SV, Yu M, Dickinson B, Makar K, Ulrich N, Böhm J, Wurscher M, Westerhoff M, Medwell S, Moonka R, Sinanan M, Fichera A, Vickers K, Grady WM.(2017) Dynamic plasma microRNAs are biomarkers for prognosis and early detection of recurrence in colorectal cancer. Br J Cancer. Oct 10;117(8):1202-1210. doi: 10.1038/bjc.2017.266. Epub 2017 Aug 15.PMID: 28809863

Mason C, Wang L, Duggan C, Imayama I, Thomas SS, Wang CY, Korde LA, McTiernan A.(2017) Gene expression in breast and adipose tissue after 12 months of weight loss and vitamin D supplementation in postmenopausal women. NPJ Breast Cancer.  Apr 21;3:15. doi: 10.1038/s41523-017-0019-5. eCollection 2017.PMID:28649655

Yu M, Carter KT, Makar KW, Vickers K, Ulrich CM, Schoen RE, Brenner D, Markowitz SD, Grady WM. (2015) MethyLight droplet digital PCR for detection and absolute quantification of infrequently methylated alleles. Epigenetics. Sep 2;10(9):803-809.

Campbell PT, Newton CC, Newcomb PA, Phipps AI, Ahnen DJ, Baron JA, Buchanan DD, Casey G, Cleary SP, Cotterchio M, Farris AB, Figueiredo JC, Gallinger S, Green RC, Haile RW, Hopper JL, Jenkins MA, Le Marchand L, Makar KW, McLaughlin JR, Potter JD, Renehan AG, Sinicrope FA, Thibodeau SN, Ulrich CM, Win AK, Lindor NM, Limburg PJ. (2015) Association between Body Mass Index and Mortality for Colorectal Cancer Survivors: Overall and by Tumor Molecular Phenotype. Cancer Epidemiol Biomarkers Prev. Aug;24(8):1229-38.

Hardikar S, Newcomb PA, Campbell PT, Win AK, Lindor NM, Buchanan DD, Makar KW, Jenkins MA, Potter JD, Phipps AI. (2015) Prediagnostic Physical Activity and Colorectal Cancer Survival: Overall and Stratified by Tumor Characteristics. Cancer Epidemiol Biomarkers Prev. Jul;24(7):1130-7.

Bhatti P, Adams C, Zhang Y, Song X, Makar KW, Sather CL, Kelsey KT, Houseman EA, Wang P. (2015) Response to "Civil time ≠ biological time: Recent options for empirically testing possible effects of chronodisruption". Chronobiol Int. Jun;32(5):699-700.

Schumacher FR, Schmit SL, Jiao S, Edlund CK, Wang H, Zhang B, Hsu L, Huang SC, Fischer CP, Harju JF, Idos GE, Lejbkowicz F, Manion FJ, McDonnell K, McNeil CE, Melas M, Rennert HS, Shi W, Thomas DC, Van Den Berg DJ, Hutter CM, Aragaki AK, Butterbach K, Caan BJ, Carlson CS, Chanock SJ, Curtis KR, Fuchs CS, Gala M, Giocannucci EL, Gogarten SM, Hayes RB, Henderson B, Hunter DJ, Jackson RD, Kolonel LN, Kooperberg C, Kury S, LaCroix A, Laurie CC, Laurie CA, Lemire M, Levine D, Ma J, Makar KW, Qu C, Taverna D, Ulrich CM, Wu K, Kono S, West DW, Berndt SI, Bezieau S, Brenner H, Campbell PT, Chan AT, Chang-Claude J, Coetzee GA, Conti DV, Duggan D, Figueiredo JC, Fortini BK, Gallinger SJ, Gauderman WJ, Giles G, Green R, Haile R, Harrison TA, Hoffmeister M, Hopper JL, Hudson TJ, Jacobs E, Iwasaki M, Jee SH, Jenkins M, Jia WH, Joshi A, Li L, Lindor NM, Matsuo K, Moreno V, Mukherjee B, Newcomb PA, Potter JD, Raskin L, Rennert G, Rosse S, Severi G, Schoen RE, Seminara D, Shu XO, Slattery ML, Tsugane S, White E, Xiang YB, Zanke BW, Zheng W, Le Marchand L, Casey G, Gruber SB, Peters U. (2015) Genome-wide association study of colorectal cancer identifies six new susceptibility loci. Nat Commun. Jul 7;6:7138.

Cheng TD, Makar KW, Neuhouser ML, Miller JW, Song X, Brown EC, Beresford SA, Zheng Y, Poole EM, Galbraith RL, Duggan DJ, Habermann N, Bailey LB, Maneval DR, Caudill MA, Toriola AT, Green R, Ulrich CM. (2015) Folate-mediated one-carbon metabolism genes and interactions with nutritional factors on colorectal cancer risk: Women's Health Initiative Observational Study. Cancer. 2015 Jun 24.

DeWitt WS, Emerson RO, Lindau P, Vignali M, Snyder TM, Desmarais C, Sanders C, Utsugi H, Warren EH, McElrath J, Makar KW, Wald A, Robins HS. (2015). Dynamics of the cytotoxic T cell response to a model of acute viral infection. J Virol. Apr 15;89(8): 4517-26

Thomas SS, Makar KW, Li L, Zheng Y, Yang P, Levy L, Rudolph RY, Lampe PD, Yan M, Markowitz SD, Bigler J, Lampe JW, Potter JD. (2015) Tissue-specific patterns of gene expression in the epithelium and stroma of normal colon in healthy individuals in an aspirin intervention trial. BMC Med Genet. Mar 24;16:18.

Passarelli MN, Newcomb PA, Makar KW, Burnett-Hartman AN, Potter JD, Upton MP, Zhu LC, Rosenfeld ME, Schwartz SM, Rutter CM. (2015). Blood lipids and colorectal polyps: testing an etiologic hypothesis using phenotypic measurements and Mendelian randomization. Cancer Causes Control. Mar;26(3):467-73

Bhatti P, Zhang Y, Song X, Makar KW, Sather CL, Kelsey KT, Houseman EA, Wang P. (2015). Nightshift work and genome-wide DNA methylation. Chronobiol Int. Feb;32(1):103-12

Bohanes P, Rankin CJ, Blanke CD, Winder T, Ulrich CM, Smalley SR, Rich TA, Martensen JA, Benson AB 3rd, Mayer RJ, Cripps CM, Danenberg K, Makar KW, Zhang W, Benedetti JK, Lenz HJ. (2015). Pharmacogenetic Analysis of INT 0144 Trial: Association of Polymorphisms with Survival and Toxicity in Rectal Cancer Patients Treated with 5-FU and Radiation. Clin Cancer Res. Jan 14

2014

Flote VG, Furberg A, McTiernan A, Frydenberg H, Ursin G, Iversen A, Lofteroed T, Ellison PT, Wist EA, Egeland T, Wilsgaard T, Makar KW, Chang-Claude J, Thune I.(2014). Gene variations in oestrogen pathways, CYP19A1 , daily 17ß-estradiol and mammographic density phenotypes in premenopausal womenBreast Cancer Res. Dec 19;16(6):499

Ristau J, Staffa J, Schrotz-King P, Gigic B, Makar KW, Hoffmeister M, Brenner H, Ulrich A, Schneider M, Ulrich CM, Habermann N. (2014). Suitability of circulating miRNAs as potential prognostic markers in colorectal cancer. Cancer Epidemiol Biomarkers Prev. Dec;23(12):2632-7

Buas MF, Levine DM, Makar KW, Utsugi H, Onstad L, Li X, Galipeau PC, Shaheen NJ, Hardie LJ, Romero Y, Bernstein L, Gammon MD, Casson AG, Bird NC, Risch HA, Ye W, Liu G, Corley DA, Blount PL, Fitzgerald RC, Whiteman DC, Wu AH, Reid BJ, Vaughan TL.(2014).  Integrative post-genome-wide association analysis of CDKN2A and TP53 SNPs and risk of esophageal adenocarcinoma. Carcinogenesis. Dec;35(12): 2740-7

Ulrich CM, Rankin C, Toriola AT, Makar KW, Altug-Teber O, Benedetti JK, Holmes RS, Smalley SR, Blanke CD, Lenz HJ. (2014). Polymorphisms in folate-metabolizing enzymes and response to 5-fluorouracil among patients with stage II or III rectal cancer (INT-0144; SWOG 9304). Cancer. Nov 1;120(21):3329-37

Adams SV, Newcomb PA, Burnett-Hartman AN, Wurscher MA, Mandelson M, Upton MP, Zhu LC, Potter JD, Makar KW. (2014). Rare circulating microRNAs as biomarkers of colorectal neoplasia. PLoS One. Oct 6;9(10)

Resler AJ, Makar KW, Heath L, Whitton J, Potter JD, Poole EM, Habermann N, Scherer D, Duggan D, Wang H, Lindor NM, Passarelli MN, Baron JA, Newcomb PA, Le Marchand L, Ulrich CM. (2014). Genetic variation in prostaglandin synthesis and related pathways, NSAID use and colorectal cancer risk in the Colon Cancer Family Registry. Carcinogenesis. Sep;35(9):2121-6

Habermann N, Makar KW, Abbenhardt C, Xiao L, Wang CY, Utsugi HK, Alfano CM, Campbell KL, Duggan C, Foster-Schubert KE, Mason CE, Imayama I, Blackburn GL, Potter JD, McTiernan A, Ulrich CM. (2014). No Effect of Caloric Restriction or Exercise on Radiation Repair Capacity. Med Sci Sports Exerc. Aug 25

Luo Y, Wong CJ, Kaz AM, Dzieciatkowski S, Carter KT, Morris SM, Wang J, Willis JE, Makar KW, Ulrich CM, Lutterbaugh JD, Shrubsole MJ, Zheng W, Markowitz SD, Grady WM. (2014). Differences in DNA methylation signatures reveal multiple pathways of progression from adenoma to colorectal cancer. Gastroenterology. 2014 Aug;147(2):418-29

Burnett-Hartman AN, Newcomb PA, Hutter CM, Peters U, Passarelli MN, Schwartz MR, Upton MP, Zhu LC, Potter JD, Makar KW. (2014). Variation in the association between colorectal cancer susceptibility loci and colorectal polyps by polyp type. Am J Epidemiol. Jul 15;180(2):223-32

Scherer D, Koepl LM, Poole EM, Balavarca Y, Xiao L, Baron JA, Hsu L, Coghill AE, Campbell PT, Kleinstein SE, Figueiredo JC, Lampe JW, Buck K, Potter JD, Kulmacz RJ, Jenkins MA, Hopper JL, Win AK, Newcomb PA, Ulrich CM, Makar KW.(2014). Genetic variation in UGT genes modify the associations of NSAIDs with risk of colorectal cancer: colon cancer family registry. Genes Chromosomes Cancer. Jul;53(7):568-78

Abbenhardt C, Miller JW, Song X, Brown EC, Cheng TY, Wener MH, Zheng Y, Toriola AT, Neuhouser ML, Beresford SA, Makar KW, Bailey LB, Maneval DR, Green R, Manson JE, Van Horn L, Ulrich CM. (2014). Biomarkers of one-carbon metabolism are associated with biomarkers of inflammation in women. J Nutr. May;144(5):714-21

Passarelli MN, Newcomb PA, Makar KW, Burnett-Hartman AN, Phipps AI, David SP, Hsu L, Harrison TA, Hutter CM, Duggan DJ, White E, Chan AT, Peters U. (2014). No association between germline variation in catechol-O-methyltransferase and colorectal cancer survival in postmenopausal women. Menopause. 2014 Apr;21(4):415-20

2013

Makar KW, Poole EM, Resler AJ, Seufert B, Curtin K, Kleinstein SE, Duggan D, Kulmacz RJ, Hsu L, Whitton J, Carlson CS, Rimorin CF, Caan BJ, Baron JA, Potter JD, Slattery ML, Ulrich CM. (2013). COX-1 (PTGS1) and COX-2 (PTGS2) polymorphisms, NSAID interactions, and risk of colon and rectal cancers in two independent populations. Cancer Causes Control.  Dec;24(12):2059-75

Phipps AI, Makar KW, Newcomb PA. (2013). Descriptive profile of PIK3CA-mutated colorectal cancer in postmenopausal women. Int J Colorectal Dis. Dec;28(12):1637-42

Wang H, Taverna D, Stram DO, Fortini BK, Cheng I, Wilkens LR, Burnett T, Makar KW, Lindor NM, Hopper JL, Gallinger S, Baron JA, Haile R, Kolonel LN, Henderson BE, Newcomb PA, Casey G, Duggan D, Ulrich CM, Le Marchand L.(2013). Genetic variation in the inflammation and innate immunity pathways and colorectal cancer risk. Cancer Epidemiol Biomarkers Prev. Nov;22(11):2094-101

Abbenhardt C, Poole EM, Kulmacz RJ, Xiao L, Curtin K, Galbraith RL, Duggan D, Hsu L, Makar KW, Caan BJ, Koepl L, Owen RW, Scherer D, Carlson CS; Genetics and Epidemiology of Colorectal Cancer Consortium (GECCO) and CCFR, Potter JD, Slattery ML, Ulrich CM (2013). Phospholipase A2G1B polymorphisms and risk of colorectal neoplasia. Int J Mol Epidemiol Genet. Sep 12;4(3):140-9

Kraus S, Hummler S, Toriola AT, Poole EM, Scherer D, Kotzmann J, Makar KW, Kazanov D, Galazan L, Naumov I, Coghill AE, Duggan D, Gigic B, Arber N, Ulrich CM. (2013). Impact of genetic polymorphisms on adenoma recurrence and toxicity in a COX2 inhibitor (celecoxib) trial: results from a pilot study. Pharmacogenet Genomics. Aug;23(8):428-37

Burnett-Hartman AN, Newcomb PA, Potter JD, Passarelli MN, Phipps AI, Wurscher MA, Grady WM, Zhu LC, Upton MP, Makar KW. (2013). Genomic aberrations occurring in subsets of serrated colorectal lesions but not conventional adenomas. Cancer Res. May 1;73(9):2863-72

Kleinstein SE, Heath L, Makar KW, Poole EM, Seufert BL, Slattery ML, Xiao L, Duggan DJ, Hsu L, Curtin K, Koepl L, Muehling J, Taverna D, Caan BJ, Carlson CS, Potter JD, Ulrich CM. (2013). Genetic variation in the lipoxygenase pathway and risk of colorectal neoplasia. Genes Chromosomes Cancer. May;52(5):437-49

Phipps AI, Buchanan DD, Makar KW, Win AK, Baron JA, Lindor NM, Potter JD, Newcomb PA. (2013). KRAS-mutation status in relation to colorectal cancer survival: the joint impact of correlated tumour markers. Br J Cancer. Apr 30;108(8):1757-64

Peters U, Jiao S, Schumacher FR, Hutter CM, Aragaki AK, Baron JA, Berndt SI, Bézieau S, Brenner H, Butterbach K, Caan BJ, Campbell PT, Carlson CS, Casey G, Chan AT, Chang-Claude J, Chanock SJ, Chen LS, Coetzee GA, Coetzee SG, Conti DV, Curtis KR, Duggan D, Edwards T, Fuchs CS, Gallinger S, Giovannucci EL, Gogarten SM, Gruber SB, Haile RW, Harrison TA, Hayes RB, Henderson BE, Hoffmeister M, Hopper JL, Hudson TJ, Hunter DJ, Jackson RD, Jee SH, Jenkins MA, Jia WH, Kolonel LN, Kooperberg C, Küry S, Lacroix AZ, Laurie CC, Laurie CA, Le Marchand L, Lemire M, Levine D, Lindor NM, Liu Y, Ma J, Makar KW, Matsuo K, Newcomb PA, Potter JD, Prentice RL, Qu C, Rohan T, Rosse SA, Schoen RE, Seminara D, Shrubsole M, Shu XO, Slattery ML, Taverna D, Thibodeau SN, Ulrich CM, White E, Xiang Y, Zanke BW, Zeng YX, Zhang B, Zheng W, Hsu L; Colon Cancer Family Registry and the Genetics and Epidemiology of Colorectal Cancer Consortium. (2013). Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis. Gastroenterology. Apr;144(4):799-807

Campbell KL, Foster-Schubert KE, Makar KW, Kratz M, Hagman D, Schur EA, Habermann N, Horton M, Abbenhardt C, Kuan LY, Xiao L, Davison J, Morgan M, Wang CY, Duggan C, McTiernan A, Ulrich CM. (2013). Gene expression changes in adipose tissue with diet- and/or exercise-induced weight loss.  Cancer Prev Res (Phila). Mar;6(3):217-31

Passarelli MN, Phipps AI, Potter JD, Makar KW, Coghill AE, Wernli KJ, White E, Chan AT, Hutter CM, Peters U, Newcomb PA. (2013). Common single-nucleotide polymorphisms in the estrogen receptor β promoter are associated with colorectal cancer survival in postmenopausal women. Cancer Res. Jan 15;73(2):767-75

Barry EL, Poole EM, Baron JA, Makar KW, Mott LA, Sandler RS, Ahnen DJ, Bresalier RS, McKeown-Eyssen GE, Ulrich CM. (2013). CYP2C9 variants increase risk of colorectal adenoma recurrence and modify associations with smoking but not aspirin treatment. Cancer Causes Control. Jan;24(1):47-54

Seufert BL, Poole EM, Whitton J, Xiao L, Makar KW, Campbell PT, Kulmacz RJ, Baron JA, Newcomb PA, Slattery ML, Potter JD, Ulrich CM. (2013). IκBKβ and NFκB1, NSAID use and risk of colorectal cancer in the Colon Cancer Family Registry. Carcinogenesis. Jan;34(1):79-85

Habermann N, Ulrich CM, Lundgreen A, Makar KW, Poole EM, Caan B, Kulmacz R, Whitton J, Galbraith R, Potter JD, Slattery ML. (2013). PTGS1, PTGS2, ALOX5, ALOX12, ALOX15, and FLAP SNPs: interaction with fatty acids in colon cancer and rectal cancer. Genes Nutr.  Jan;8(1):115-26

2012

Hagman DK, Kuzma JN, Larson I, Foster-Schubert KE, Kuan LY, Cignarella A, Geamanu E, Makar KW, Gottlieb JR, Kratz M.(2012). Characterizing and quantifying leukocyte populations in human adipose tissue: impact of enzymatic tissue processing. J Immunol Methods. Dec 14;386(1-2):50-9

Phipps AI, Buchanan DD, Makar KW, Burnett-Hartman AN, Coghill AE, Passarelli MN, Baron JA, Ahnen DJ, Win AK, Potter JD, Newcomb PA. (2012). BRAF mutation status and survival after colorectal cancer diagnosis according to patient and tumor characteristics. Cancer Epidemiol Biomarkers Prev. Oct;21(10):1792-8

Haug U, Poole EM, Xiao L, Curtin K, Duggan D, Hsu L, Makar KW, Peters U, Kulmacz RJ, Potter JD, Koepl L, Caan BJ, Slattery ML, Ulrich CM. (2012). Glutathione peroxidase tagSNPs: associations with rectal cancer but not with colon cancer. Genes Chromosomes Cancer. Jun;51(6):598-605

Iversen A, Thune I, McTiernan A, Makar KW, Wilsgaard T, Ellison PT, Jasienska G, Flote V, Poole EM, Furberg AS. (2012). Genetic polymorphism CYP17 rs2486758 and metabolic risk factors predict daily salivary 17β-estradiol concentration in healthy premenopausal Norwegian women. The EBBA-I study. J Clin Endocrinol Metab. May;97(5):E852-7

Poole EM, Curtin K, Hsu L, Duggan DJ, Makar KW, Xiao L, Carlson CS, Caan BJ, Potter JD, Slattery ML, Ulrich CM. (2012). Genetic variability in IL23R and risk of colorectal adenoma and colorectal cancer. Cancer Epidemiol. 2012 Apr;36(2):e104-10

Raccor BS, Claessens AJ, Dinh JC, Park JR, Hawkins DS, Thomas SS, Makar KW, McCune JS, Totah RA. Potential contribution of cytochrome P450 2B6 to hepatic 4-hydroxycyclophosphamide formation in vitro and in vivo. (2012) Drug Metab Dispos. Jan;40(1):54-63. doi: 10.1124/dmd.111.039347. Epub 2011 Oct 5. PMID: 21976622

2011

Poole EM, Curtin K, Hsu L, Duggan DJ, Makar KW, Xiao L, Carlson CS, Caan BJ, Potter JD, Slattery ML, Ulrich CM. Genetic variability in IL23R and risk of colorectal adenoma and colorectal cancer. Cancer Epidemiol. 2011 Dec 6.

Poole EM, Curtin K, Hsu L, Kulmacz RJ, Duggan DJ, Makar KW, Xiao L, Carlson CS, Slattery ML, Caan BJ, Potter JD, Ulrich CM. Genetic variability in EGFR, Src and HER2 and risk of colorectal adenoma and cancer. Int J Mol Epidemiol Genet. 2011;2(4):300-15.

Coghill, A.E., Newcomb, P.A., Poole, E.M., Hutter, C.M., Makar, K.W., Duggan, D.J., Potter, J.D., and Ulrich, C.M. (2011). Genetic Variation in Inflammatory Pathways is Related to Colorectal Cancer Survival. Clin Cancer Res. 17(22):7139-47

Passarelli, M.N., Coghill, A.E., Hutter, C.M., Zheng, Y., Makar, K.W., Potter, J.D., and Newcomb, P.A. (2011). Common colorectal cancer risk variants in SMAD7 are associated with survival among prediagnostic nonsteroidal anti-inflammatory drug users: A population-based study of postmenopausal women. Genes Chromosomes Cancer 50, 875-886.

Yong, M., Schwartz, S.M., Atkinson, C., Makar, K.W., Thomas, S.S., Stanczyk, F.Z., Westerlind, K.C., Newton, K.M., Holt, V.L., Leisenring, W.M., et al. (2011). Associations between polymorphisms in glucuronidation and sulfation enzymes and sex steroid concentrations in premenopausal women in the United States. J Steroid Biochem Mol Biol 124, 10-18.

Peters, U., Hutter, C.M., Hsu, L., Schumacher, F.R., Conti, D.V., Carlson, C.S., Edlund, C.K., Haile, R.W., Gallinger, S., Zanke, B.W., et al. (2011). Meta-analysis of new genome-wide association studies of colorectal cancer risk. Hum Genet. Jul 15

Burnett-Hartman, A.N., Newcomb, P.A., Mandelson, M.T., Galloway, D.A., Madeleine, M.M., Wurscher, M.A., Carter, J.J., Makar, K.W., Potter, J.D., and Schwartz, S.M. (2011). No evidence for human papillomavirus in the etiology of colorectal polyps. Cancer Epidemiol Biomarkers Prev 20, 2288-2297.

Burnett-Hartman, A.N., Newcomb, P.A., Mandelson, M.T., Adams, S.V., Wernli, K.J., Shadman, M., Wurscher, M.A., and Makar, K.W. (2011). Colorectal polyp type and the association with charred meat consumption, smoking, and microsomal epoxide hydrolase polymorphisms. Nutr Cancer 63, 583-592.

Curtin, K., Ulrich, C.M., Samowitz, W.S., Wolff, R.K., Duggan, D.J., Makar, K.W., Caan, B.J., and Slattery, M.L. (2011). Candidate pathway polymorphisms in one-carbon metabolism and risk of rectal tumor mutations. International journal of molecular epidemiology and genetics 2(1), 1-8.

Navarro, S.L., Chen, Y., Li, L., Li, S.S., Chang, J.L., Schwarz, Y., King, I.B., Potter, J.D., Bigler, J., and Lampe, J.W. (2011). UGT1A6 and UGT2B15 polymorphisms and acetaminophen conjugation in response to a randomized, controlled diet of select fruits and vegetables. Drug metabolism and disposition: the biological fate of chemicals 39, 1650-1657.

Navarro, S.L., Saracino, M.R., Makar, K.W., Thomas, S.S., Li, L., Zheng, Y., Levy, L., Schwarz, Y., Bigler, J., Potter, J.D., et al. (2011). Determinants of aspirin metabolism in healthy men and women: effects of dietary inducers of UDP-glucuronosyltransferases. Journal of nutrigenetics and nutrigenomics 4, 110-118.

Galbraith, R.L., Poole, E.M., Duggan, D., Muehling, J., Hsu, L., Makar, K., Xiao, L., Potter, J.D., and Ulrich, C.M. (2011). Polymorphisms in WNT6 and WNT10A and colorectal adenoma risk. Nutr Cancer 63, 558-564.

2010

Poole, E.M., Hsu, L., Xiao, L., Kulmacz, R.J., Carlson, C.S., Rabinovitch, P.S., Makar, K.W., Potter, J.D., and Ulrich, C.M. (2010). Genetic variation in prostaglandin E2 synthesis and signaling, prostaglandin dehydrogenase, and the risk of colorectal adenoma. Cancer Epidemiol Biomarkers Prev 19, 547-557.

Yong, M., Schwartz, S.M., Atkinson, C., Makar, K.W., Thomas, S.S., Newton, K.M., Aiello Bowles, E.J., Holt, V.L., Leisenring, W.M., and Lampe, J.W. (2010). Associations between polymorphisms in glucuronidation and sulfation enzymes and mammographic breast density in premenopausal women in the United States. Cancer Epidemiol Biomarkers Prev 19, 537-546.

Chang, J.L., Chen, G., Ulrich, C.M., Bigler, J., King, I.B., Schwarz, Y., Li, S., Li, L., Potter, J.D., and Lampe, J.W. (2010). DNA damage and repair: fruit and vegetable effects in a feeding trial. Nutr Cancer 62, 329-335.

Kocarnik, J.D., Hutter, C.M., Slattery, M.L., Berndt, S.I., Hsu, L., Duggan, D.J., Muehling, J., Caan, B.J., Beresford, S.A., Rajkovic, A., et al. (2010). Characterization of 9p24 risk locus and colorectal adenoma and cancer: gene-environment interaction and meta-analysis. Cancer Epidemiol Biomarkers Prev 19, 3131-3139.

Hutter, C.M., Slattery, M.L., Duggan, D.J., Muehling, J., Curtin, K., Hsu, L., Beresford, S.A., Rajkovic, A., Sarto, G.E., Marshall, J.R., et al. (2010). Characterization of the association between 8q24 and colon cancer: gene-environment exploration and meta-analysis. BMC Cancer 10, 670.

Wernli, K.J., Newcomb, P.A., Wang, Y., Makar, K.W., Shadman, M., Chia, V.M., Burnett-Hartman, A., Wurscher, M.A., Zheng, Y., and Mandelson, M.T. (2010). Body size, IGF and growth hormone polymorphisms, and colorectal adenomas and hyperplastic polyps. Growth Horm IGF Res 20, 305-309.

2009

Poole, E.M., Bigler, J., Whitton, J., Sibert, J.G., Potter, J.D., and Ulrich, C.M. (2009). C-reactive protein genotypes and haplotypes, polymorphisms in NSAID-metabolizing enzymes, and risk of colorectal polyps. Pharmacogenet Genomics 19, 113-120.

Campbell, K.L., Makar, K.W., Kratz, M., Foster-Schubert, K.E., McTiernan, A., and Ulrich, C.M. (2009). A pilot study of sampling subcutaneous adipose tissue to examine biomarkers of cancer risk. Cancer Prev Res (Phila) 2, 37-42.

Campbell, P.T., Curtin, K., Ulrich, C.M., Samowitz, W.S., Bigler, J., Velicer, C.M., Caan, B., Potter, J.D., and Slattery, M.L. (2009). Mismatch repair polymorphisms and risk of colon cancer, tumour microsatellite instability and interactions with lifestyle factors. Gut 58, 661-667.

Dong, L.M., Ulrich, C.M., Hsu, L., Duggan, D.J., Benitez, D.S., White, E., Slattery, M.L., Farin, F.M., Makar, K.W., Carlson, C.S., et al. (2009). Vitamin D related genes, CYP24A1 and CYP27B1, and colon cancer risk. Cancer Epidemiol Biomarkers Prev 18, 2540-2548.

Navarro, S.L., Peterson, S., Chen, C., Makar, K.W., Schwarz, Y., King, I.B., Li, S.S., Li, L., Kestin, M., and Lampe, J.W. (2009). Cruciferous vegetable feeding alters UGT1A1 activity: diet- and genotype-dependent changes in serum bilirubin in a controlled feeding trial. Cancer Prev Res (Phila) 2, 345-352.

Saracino, M.R., Bigler, J., Schwarz, Y., Chang, J.L., Li, S., Li, L., White, E., Potter, J.D., and Lampe, J.W. (2009). Citrus fruit intake is associated with lower serum bilirubin concentration among women with the UGT1A1*28 polymorphism. J Nutr 139, 555-560.

2008 and earlier

Berndt, S.I., Potter, J.D., Hazra, A., Yeager, M., Thomas, G., Makar, K.W., Welch, R., Cross, A.J., Huang, W.Y., Schoen, R.E., et al. (2008). Pooled analysis of genetic variation at chromosome 8q24 and colorectal neoplasia risk. Hum Mol Genet 17, 2665-2672.

Jung, A.Y., Poole, E.M., Bigler, J., Whitton, J., Potter, J.D., and Ulrich, C.M. (2008). DNA methyltransferase and alcohol dehydrogenase: gene-nutrient interactions in relation to risk of colorectal polyps. Cancer Epidemiol Biomarkers Prev 17, 330-338.

Maruti, S.S., Chang, J.L., Prunty, J.A., Bigler, J., Schwarz, Y., Li, S.S., Li, L., King, I.B., Potter, J.D., and Lampe, J.W. (2008). Serum beta-glucuronidase activity in response to fruit and vegetable supplementation: a controlled feeding study. Cancer Epidemiol Biomarkers Prev 17, 1808-1812.

Curtin, K., Slattery, M.L., Ulrich, C.M., Bigler, J., Levin, T.R., Wolff, R.K., Albertsen, H., Potter, J.D., and Samowitz, W.S. (2007). Genetic polymorphisms in one-carbon metabolism: associations with CpG island methylator phenotype (CIMP) in colon cancer and the modifying effects of diet. Carcinogenesis 28, 1672-1679.

Curtin, K., Ulrich, C.M., Samowitz, W.S., Bigler, J., Caan, B., Potter, J.D., and Slattery, M.L. (2007). Thymidylate synthase polymorphisms and colon cancer: associations with tumor stage, tumor characteristics and survival. Int J Cancer 120, 2226-2232.

Goode, E.L., Potter, J.D., Bamlet, W.R., Rider, D.N., and Bigler, J. (2007). Inherited variation in carcinogen-metabolizing enzymes and risk of colorectal polyps. Carcinogenesis 28, 328-341.

Bigler, J., Sibert, J.G., Poole, E.M., Carlson, C.S., Potter, J.D., and Ulrich, C.M. (2007). Polymorphisms predicted to alter function in prostaglandin E2 synthase and prostaglandin E2 receptors. Pharmacogenet Genomics 17, 221-227.

Chang, J.L., Bigler, J., Schwarz, Y., Li, S.S., Li, L., King, I.B., Potter, J.D., and Lampe, J.W. (2007). UGT1A1 polymorphism is associated with serum bilirubin concentrations in a randomized, controlled, fruit and vegetable feeding trial. J Nutr 137, 890-897.

Chen, Y., Kuehl, G.E., Bigler, J., Rimorin, C.F., Schwarz, Y., Shen, D.D., and Lampe, J.W. (2007). UGT1A6 polymorphism and salicylic acid glucuronidation following aspirin. Pharmacogenet Genomics 17, 571-579.

Poole, E.M., Bigler, J., Whitton, J., Sibert, J.G., Kulmacz, R.J., Potter, J.D., and Ulrich, C.M. (2007). Genetic variability in prostaglandin synthesis, fish intake and risk of colorectal polyps. Carcinogenesis 28, 1259-1263.

Poole, E.M., Bigler, J., Whitton, J., Sibert, J.G., Potter, J.D., and Ulrich, C.M. (2006). Prostacyclin synthase and arachidonate 5-lipoxygenase polymorphisms and risk of colorectal polyps. Cancer Epidemiol Biomarkers Prev 15, 502-508.

Robien, K., Bigler, J., Yasui, Y., Potter, J.D., Martin, P., Storb, R., and Ulrich, C.M. (2006). Methylenetetrahydrofolate reductase and thymidylate synthase genotypes and risk of acute graft-versus-host disease following hematopoietic cell transplantation for chronic myelogenous leukemia. Biol Blood Marrow Transplant 12, 973-980.

Robien, K., Schubert, M.M., Chay, T., Bigler, J., Storb, R., Yasui, Y., Potter, J.D., and Ulrich, C.M. (2006). Methylenetetrahydrofolate reductase and thymidylate synthase genotypes modify oral mucositis severity following hematopoietic stem cell transplantation. Bone Marrow Transplant 37, 799-800.

Lindor, N.M., Smalley, R., Barker, M., Bigler, J., Krumroy, L.M., Lum-Jones, A., Plummer, S.J., Selander, T., Thomas, S., Youash, M., et al. (2006). Ascending the learning curve--MSI testing experience of a six-laboratory consortium. Cancer Biomark 2, 5-9.

Yu, J.H., Bigler, J., Whitton, J., Potter, J.D., and Ulrich, C.M. (2006). Mismatch repair polymorphisms and colorectal polyps: hMLH1-93G>A variant modifies risk associated with smoking. Am J Gastroenterol 101, 1313-1319.

Chia, V.M., Newcomb, P.A., Bigler, J., Morimoto, L.M., Thibodeau, S.N., and Potter, J.D. (2006). Risk of microsatellite-unstable colorectal cancer is associated jointly with smoking and nonsteroidal anti-inflammatory drug use. Cancer Res 66, 6877-6883.

Thomas, S.S., Li, S.S., Lampe, J.W., Potter, J.D., and Bigler, J. (2006). Genetic variability, haplotypes, and htSNPs for exons 1 at the human UGT1A locus. Hum Mutat 27, 717.

Kuehl, G.E., Bigler, J., Potter, J.D., and Lampe, J.W. (2006). Glucuronidation of the aspirin metabolite salicylic acid by expressed UDP-glucuronosyltransferases and human liver microsomes. Drug metabolism and disposition: the biological fate of chemicals 34, 199-202.

Kuehl, G.E., Lampe, J.W., Potter, J.D., and Bigler, J. (2005). Glucuronidation of nonsteroidal anti-inflammatory drugs: identifying the enzymes responsible in human liver microsomes. Drug metabolism and disposition: the biological fate of chemicals 33, 1027-1035.

Li, S.S., Bigler, J., Lampe, J.W., Potter, J.D., and Feng, Z. (2005). FDR-controlling testing procedures and sample size determination for microarrays. Stat Med 24, 2267-2280.

Bigler, J., Ulrich, C.M., Kawashima, T., Whitton, J., and Potter, J.D. (2005). DNA repair polymorphisms and risk of colorectal adenomatous or hyperplastic polyps. Cancer Epidemiol Biomarkers Prev 14, 2501-2508.

Peterson, S., Bigler, J., Horner, N.K., Potter, J.D., and Lampe, J.W. (2005). Cruciferae interact with the UGT1A1*28 polymorphism to determine serum bilirubin levels in humans. J Nutr 135, 1051-1055.

Robien, K., Curtin, K., Ulrich, C.M., Bigler, J., Samowitz, W., Caan, B., Potter, J.D., and Slattery, M.L. (2005). Microsomal epoxide hydrolase polymorphisms are not associated with colon cancer risk. Cancer Epidemiol Biomarkers Prev 14, 1350-1352.

Bigler, J. (2005). Accuracy and reproducibility of short tandem repeat assays. Cancer Epidemiol Biomarkers Prev 14, 1581; author reply 1581-1582.

Morimoto, L.M., Newcomb, P.A., White, E., Bigler, J., and Potter, J.D. (2005). Insulin-like growth factor polymorphisms and colorectal cancer risk. Cancer Epidemiol Biomarkers Prev 14, 1204-1211.

Morimoto, L.M., Newcomb, P.A., White, E., Bigler, J., and Potter, J.D. (2005). Variation in plasma insulin-like growth factor-1 and insulin-like growth factor binding protein-3: genetic factors. Cancer Epidemiol Biomarkers Prev 14, 1394-1401.

Morimoto, L.M., Newcomb, P.A., White, E., Bigler, J., and Potter, J.D. (2005). Variation in plasma insulin-like growth factor-1 and insulin-like growth factor binding protein-3: personal and lifestyle factors (United States). Cancer Causes Control 16, 917-927.

Ulrich, C.M., Carlson, C.S., Sibert, J., Poole, E.M., Yu, J.H., Wang, L.H., Sparks, R., Potter, J.D., and Bigler, J. (2005). Thromboxane synthase (TBXAS1) polymorphisms in African-American and Caucasian populations: evidence for selective pressure. Hum Mutat 26, 394-395.

Ulrich, C.M., Curtin, K., Potter, J.D., Bigler, J., Caan, B., and Slattery, M.L. (2005). Polymorphisms in the reduced folate carrier, thymidylate synthase, or methionine synthase and risk of colon cancer. Cancer Epidemiol Biomarkers Prev 14, 2509-2516.

Ulrich, C.M., Curtin, K., Samowitz, W., Bigler, J., Potter, J.D., Caan, B., and Slattery, M.L. (2005). MTHFR variants reduce the risk of G:C->A:T transition mutations within the p53 tumor suppressor gene in colon tumors. J Nutr 135, 2462-2467.

Ulrich, C.M., Whitton, J., Yu, J.H., Sibert, J., Sparks, R., Potter, J.D., and Bigler, J. (2005). PTGS2 (COX-2) -765G > C promoter variant reduces risk of colorectal adenoma among nonusers of nonsteroidal anti-inflammatory drugs. Cancer Epidemiol Biomarkers Prev 14, 616-619.

Newcomb, P.A., Bush, A.C., Stoner, G.L., Lampe, J.W., Potter, J.D., and Bigler, J. (2004). No evidence of an association of JC virus and colon neoplasia. Cancer Epidemiol Biomarkers Prev 13, 662-666.

Ulrich, C.M., Bigler, J., Sparks, R., Whitton, J., Sibert, J.G., Goode, E.L., Yasui, Y., and Potter, J.D. (2004). Polymorphisms in PTGS1 (=COX-1) and risk of colorectal polyps. Cancer Epidemiol Biomarkers Prev 13, 889-893.

Sparks, R., Bigler, J., Sibert, J.G., Potter, J.D., Yasui, Y., and Ulrich, C.M. (2004). TGFbeta1 polymorphism (L10P) and risk of colorectal adenomatous and hyperplastic polyps. Int J Epidemiol 33, 955-961.

Sparks, R., Ulrich, C.M., Bigler, J., Tworoger, S.S., Yasui, Y., Rajan, K.B., Porter, P., Stanczyk, F.Z., Ballard-Barbash, R., Yuan, X., et al. (2004). UDP-glucuronosyltransferase and sulfotransferase polymorphisms, sex hormone concentrations, and tumor receptor status in breast cancer patients. Breast Cancer Res 6, R488-498.

Robien, K., Ulrich, C.M., Bigler, J., Yasui, Y., Gooley, T., Bruemmer, B., Potter, J.D., and Radich, J.P. (2004). Methylenetetrahydrofolate reductase genotype affects risk of relapse after hematopoietic cell transplantation for chronic myelogenous leukemia. Clin Cancer Res 10, 7592-7598.

Boland, C.R., Bigler, J., Newcomb, P.A., Lampe, J.W., and Potter, J.D. (2004). Evidence for an association between JC virus and colorectal neoplasia. Cancer Epidemiol Biomarkers Prev 13, 2285-2286; author reply 2286.

Curtin, K., Bigler, J., Slattery, M.L., Caan, B., Potter, J.D., and Ulrich, C.M. (2004). MTHFR C677T and A1298C polymorphisms: diet, estrogen, and risk of colon cancer. Cancer Epidemiol Biomarkers Prev 13, 285-292.

Goode, E.L., Potter, J.D., Bigler, J., and Ulrich, C.M. (2004). Methionine synthase D919G polymorphism, folate metabolism, and colorectal adenoma risk. Cancer Epidemiol Biomarkers Prev 13, 157-162.

King, I.B., Satia-Abouta, J., Thornquist, M.D., Bigler, J., Patterson, R.E., Kristal, A.R., Shattuck, A.L., Potter, J.D., and White, E. (2002). Buccal cell DNA yield, quality, and collection costs: comparison of methods for large-scale studies. Cancer Epidemiol Biomarkers Prev 11, 1130-1133.

Ulrich, C.M., Bigler, J., Bostick, R., Fosdick, L., and Potter, J.D. (2002). Thymidylate synthase promoter polymorphism, interaction with folate intake, and risk of colorectal adenomas. Cancer Res 62, 3361-3364.

Ulrich, C.M., Bigler, J., Sibert, J., Greene, E.A., Sparks, R., Carlson, C.S., and Potter, J.D. (2002). Cyclooxygenase 1 (COX1) polymorphisms in African-American and Caucasian populations. Hum Mutat 20, 409-410.

Bigler, J., Whitton, J., Lampe, J.W., Fosdick, L., Bostick, R.M., and Potter, J.D. (2001). CYP2C9 and UGT1A6 genotypes modulate the protective effect of aspirin on colon adenoma risk. Cancer Res 61, 3566-3569.

Kim, H.S., Newcomb, P.A., Ulrich, C.M., Keener, C.L., Bigler, J., Farin, F.M., Bostick, R.M., and Potter, J.D. (2001). Vitamin D receptor polymorphism and the risk of colorectal adenomas: evidence of interaction with dietary vitamin D and calcium. Cancer Epidemiol Biomarkers Prev 10, 869-874.

Ulrich, C.M., Bigler, J., Whitton, J.A., Bostick, R., Fosdick, L., and Potter, J.D. (2001). Epoxide hydrolase Tyr113His polymorphism is associated with elevated risk of colorectal polyps in the presence of smoking and high meat intake. Cancer Epidemiol Biomarkers Prev 10, 875-882.

Ulrich, C.M., Yasui, Y., Storb, R., Schubert, M.M., Wagner, J.L., Bigler, J., Ariail, K.S., Keener, C.L., Li, S., Liu, H., et al. (2001). Pharmacogenetics of methotrexate: toxicity among marrow transplantation patients varies with the methylenetetrahydrofolate reductase C677T polymorphism. Blood 98, 231-234.

Ulrich, C.M., Bigler, J., Velicer, C.M., Greene, E.A., Farin, F.M., and Potter, J.D. (2000). Searching expressed sequence tag databases: discovery and confirmation of a common polymorphism in the thymidylate synthase gene. Cancer Epidemiol Biomarkers Prev 9, 1381-1385.

Ulrich, C.M., Kampman, E., Bigler, J., Schwartz, S.M., Chen, C., Bostick, R., Fosdick, L., Beresford, S.A., Yasui, Y., and Potter, J.D. (2000). Lack of association between the C677T MTHFR polymorphism and colorectal hyperplastic polyps. Cancer Epidemiol Biomarkers Prev 9, 427-433.