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Publications

20192018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 | 1999-1995 

2019

  • Navarro SL, Tarkhan A, Shojaie A, Randolph TW, Gu H, Djukovic D, Osterbauer KJ, Hullar MA, Kratz M, Neuhouser ML, Lampe PD, Raftery D, Lampe JW. Plasma metabolomics profiles suggest beneficial effects of a low-glycemic load dietary pattern on inflammation and energy metabolism. Am J Clin Nutr. 2019 Oct 110(4):984-992. doi: 10.1093/ajcn/nqz169. PMID: 31432072.
  • Lastwika KJ, Dunn CA, Solan JL, Lampe PD. Phosphorylation of connexin43 at MAPK, PKC or CK1 sites each distinctly alter the kinetics of epidermal wound repair. J Cell Sci. 2019 Sep 23;132(18). pii: jcs234633. doi: 10.1242/jcs.234633.
  • Garrison CB, Zhang Y, Navarro SL, Randolph TW, Hullar MAJ, Kratz M, Neuhouser ML, Raftery D, Lampe PD, Lampe JW. Proteomic analysis of plasma reveals fat mass influences cancer-related pathways in healthy humans fed controlled diets differing in glycemic load. Cancer Prev Res (Phila). 2019 Sep; 12(9):567-578. doi: 10.1158/1940-6207.CAPR-19-0175. PMID: 31266826. PMC6726515
  • Solan JL, Márquez-Rosado L, Lampe PD. Cx43 phosphorylation-mediated effects on ERK and Akt protect against ischemia reperfusion injury and alter the stability of the stress-inducible protein NDRG1. J Biol Chem. 2019 Aug 2; 294(31):11762-11771. PMID: 31189653; PMC6682735.
  • Cotter ML, Boitano S, Lampe PD, Solan JL, Vagner J, Ek-Vitorin JF, Burt JM. The lipidated connexin mimetic peptide, SRPTEKT-Hdc, is a potent inhibitor of Cx43 channels with specificity for the pS368 phospho-isoform. Am J Physiol Cell Physiol. 2019 Jul 31;. doi: 10.1152/ajpcell.00160.2019. [Epub ahead of print] PubMed PMID: 31365296.
  • Yang W, Lampe PD, Kensel-Hammes P, Hesson J, Ware CB, Crisa L, Cirulli V. Connexin 43 Functions as a Positive Regulator of Stem Cell Differentiation into Definitive Endoderm and Pancreatic Progenitors. iScience. 2019 Jul 24; 19:450-460. doi: 10.1016/j.isci.2019.07.033. PMID: 31430690. PMC31430690.
  • Wu W, Pierce LA, Zhang Y, Pipavath SNJ, Randolph TW, Lastwika KJ, Lampe PD, Houghton AM, Liu H, Xia L, Kinahan PE. Comparison of prediction models with radiological semantic features and radiomics in lung cancer diagnosis of the pulmonary nodules: a case-control study. Eur Radiol. 2019 May 21;. doi: 10.1007/s00330-019-06213-9. [Epub ahead of print] PubMed PMID: 31115618.
  • Lastwika KJ, Kargl J, Zhang Y, Zhu X, Lo E, Shelley D, Ladd JJ, Wu W, Kinahan P, Pipavath S NJ, Randolph TW, Shipley M, Lampe PD, Houghton AM. Tumor-derived Autoantibodies Identify Malignant Pulmonary Nodules. Am J Respir Crit Care Med. 2019 May 15;199(10):1257-1266. doi: 10.1164/rccm.201804-0628OC. PubMed PMID: 30422669; PubMed Central PMCID: PMC6519849.
  • DeLalio LJ, Billaud M, Ruddiman CA, Johnstone SR, Butcher JT, Wolpe AG, Jin X, Keller TCS 4th, Keller AS, Rivière T, Good ME, Best AK, Lohman AW, Swayne LA, Penuela S, Thompson RJ, Lampe PD, Yeager M, Isakson BE. Constitutive SRC-mediated phosphorylation of pannexin 1 at tyrosine 198 occurs at the plasma membrane. J Biol Chem. 2019 Apr 26;294(17):6940-6956. PMID: 30814251; PMCID: PMC6497939.
  • Freitas-Andrade M, Wang N, Bechberger JF, De Bock M, Lampe PD, Leybaert L, Naus CC. Targeting MAPK phosphorylation of Connexin43 provides neuroprotection in stroke. J Exp Med. 2019 Apr 1; 216(4):916-935. doi: 10.1084/jem.20171452. PMID:30872361. PMC30872361
  • Luebeck GE, Hazelton WD, Curtius K, Maden SK, Yu M, Carter KT, Burke W, Lampe PD, Li CI, Ulrich CM, Newcomb PA, Westerhoff M, Kaz AM, Luo Y, Inadomi JM, Grady WM. Implications of Epigenetic Drift in Colorectal Neoplasia. Cancer Res. 2019 Feb 1;79(3):495-504. Epub 2018 Oct 5. PubMed PMID: 30291105; PMC6359943.
  • Navarro SL, Herrero M, Martinez H, Zhang Y, Ladd J, Lo E, Shelley D, Randolph TW, Lampe JW, Lampe PD. Differences in serum biomarkers between combined glucosamine and chondroitin versus celecoxib in a randomized, double-blind trial in osteoarthritis patients. Antiinflamm Antiallergy Agents Med Chem. 2019 Jan 14;. [Epub ahead of print] PubMed PMID: 30648524.

2018

  • Laird, DW, Lampe, PD (2018) “Therapeutic strategies targeting connexins” Nature Reviews Drug Disc. 17 (12), 905-921; PMID: 30310236; PubMed Central PMCID: PMC6461534.
  • Rho, JH.**, Ladd, JJ**, Li, CI, Potter, JD, Zhang, Y., Shelley, D, Shibata, D. Coppola, D, Yamada, H, Toyoda, H, Tada, T, Kumada, T, Brenner, DE, Hanash, SM, Lampe, PD (2018) “Protein and glycomic plasma markers for early detection of adenoma and colon cancer” Gut, 67: 473-484. PMC5420499
  • Mesnil M, Aasen T, Boucher J, Chépied A, Cronier L, Defamie N, Kameritsch P, Laird DW, Lampe PD, Lathia JD, Leithe E, Mehta PP, Monvoisin A, Pogoda K, Sin WC, Tabernero A, Yamasaki H, Yeh ES, Dagli MLZ, Naus CC. (2018) “An update on minding the gap in cancer.” Biochim Biophys Acta. 1860 (2018) 237–243.
  • Solan, J.L., Lampe, P.D. (2018) “Spatio-temporal regulation of connexin phosphorylation and gap junction dynamics”.  BBA-Biomembranes. 1860 (2018) 83-90.    PMC5640473
  • Ginos, BNR, Navarro, SL, Schwarz, Y, Gu, H, Wang, D, Randolph, TW, Shojaie, A, Hullar, MAJ, Lampe, PD, Kratz, M, Neuhouser, ML, Raftery, D, Lampe, JW (2018) Circulating bile acids in healthy adults respond differently to a dietary pattern characterized by whole grains, legumes and fruits and vegetables compared to a diet high in refined grains and added sugars: a randomized, controlled, crossover feeding study” Metabolism, 83:197-204. PMC5960615
  • Slavi N, Toychiev A, Kosmidis S, Ackert J, Bloomfield S, Wulff H, Viswanathan S, Lampe PD, Srinivas M. (2018) "Suppression of Connexin 43 Phosphorylation Promotes Astrocyte Survival and Vascular Regeneration in Proliferative Retinopathy" Proc Natl Acad Sci, https://doi.org/10.1073/pnas.1803907115 epub published ahead of print.
  • Kam, CY, Dubash, A, Magistrati, E, Polo, S, Satchell, K, Sheikh, F, Lampe, PD, Green, KJ (2018) “Desmosomal Regulation of Gap Junctions via Ras: Implications for Cardiocutaneous Disease.” J. Cell Biol. In press.

2017

  • Garrison, CB**, Lastwika, KJ**, Zhang, Y., Li, CI., Lampe, PD. (2017) “Proteomic Analysis, Immune Activation and Pathway Interconnections with Obesity” J. Proteome Res. 16(1):274-287. PMC5234688
  • Wang, X, Shojaie, A, Zhang, Y, Shelley, D, Lampe, PD, Levy, L, Peters, U, Potter, JD White, E, Lampe, JW (2017) “Exploratory plasma proteomic analysis in a randomized crossover trial of aspirin among healthy men and women” PLOS One 2(5):e0178444.    PMC5444835
  • Leybaert, L, Lampe, PD, Dhein, S, Kwak, BR, Ferdinandy, P, Beyer, EC, Laird, DW, Naus, CC, Green, CR, Schulz, R. (2017) “Connexins in cardiovascular health and disease: pharmacological implications.” Pharmacological Reviews (IF=17.1), 69(4):396-478.    PMC5612248
  • Laird, DW, Naus, CC, Lampe PD (2017) “Snapshot:Connexin Gap Junction Proteins and Linked Diseases” Cell, 170, 1260-1260.e1.
  • Jacobsen, NL, Pontifex, TK, Li, H, Solan, JL, Lampe, PD, Sorgen, PL, Burt, JM (2017) “Phosphorylation-dependent regulation of channel and growth suppressive properties of Cx37” J Cell Science, 130(19):3308-3321.  PMC5665438
  • Miles FL, Navarro SL, Schwarz Y, Gu H, Djukovic D, Randolph TW, Shojaie A, Kratz M, Hullar MAJ, Lampe PD, Neuhouser ML, Raftery D, Lampe JW. (2017) Plasma metabolite abundances are associated with urinary enterolactone excretion in healthy participants on controlled diets. Food Funct., 8(9):3209-3218.    PMC5607107
  • Crassous, P-A, Shu, P, Huang, C, Gordan, R, Brouckaert, P, Lampe, PD, Xie, L-H, Beuve, A (2017) “A newly identified NO-sensor guanylyl cyclase/connexin 43 complex is involved in cardiac electrical function”. J Am Heart Assoc Dec 21;6(12).  PMC5778997 2018

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2016

  • Solan, JL, Lampe PD (2016) “Kinase programs spatiotemporally regulate gap junction assembly and disassembly: effects on wound repair” Seminars Cell Dev. Biol. 50:40-8. PMCID: PMC4779375
  • Morel, S, Christoffersen, Axelsen, LN, Montecucco, F, Rochemont, V, Frias, MA, Mach, F, James, RW, Naus, CC, Chanson, M, Lampe, PD, Nielsen, MS, Nielsen, LB, Kwak, BR (2106) “Sphingosine-1-Phosphate reduces ischemia/reperfusion injury by phosphorylating the gap junction protein Connexin43” Cardiovascular Res, 109(3):385-96. PMCID: PMC4752044
  • Puebla, C, Cisterna, BA, Salas, DP, Delgado-López, F, Lampe, PD and Sáez, JC. (2016) “Linoleic Acid Permeabilizes Gastric Epithelial Cells by Increasing Connexin43 Levels in the Cell Membrane Via a GPR40- and Akt-Dependent Mechanism”. BBA, Mol. Cell. Biol. Lipids, 1861, 439-448. PMC4821727
  • Egbert, JR, Uliasz, TF, Shuhaibar, LC, Geerts, A, Wunder, F, Kleiman, RJ, Humphrey, JM, Lampe, PD, Artemyev, NO, Rybalkin, SD, Beavo, JA, Movsesian, MA, and Jaffe, LA (2016) “Luteinizing Hormone Causes Phosphorylation and Activation of the cyclic GMP Phosphodiesterase PDE5 in Rat Ovarian Follicles Contributing, Together with PDE1 Activity, to the Resumption of Meiosis” Biol Reproduct, 94(5):110, 1-11. PMCID: PMC2572224
  • Böhm, J, Pianka, F, Stüttgen, N, Gigic, B, **Rho, J-H, Zhang, Y, Habermann, N, Schrotz-King, P, Lampe, PD, Ulrich, A, Diener, M, Ulrich, CM. (2016) “Discovery of novel plasma proteins as biomarkers for the development ofincisional hernias after midline incision in colorectal cancer patients: the ColoCare Study.” Surgery S0039-6060(16)30459-7. PMC5560863
  • AAsen, T., Mesnil, M., Naus, C.C., Lampe, P.D., Laird, D.W. (2016) “Gap Junctions and Cancer: Communicating for 50 Years” Nature Reviews Cancer 16(12):775-788.    PMC5279857
  • Jabr RI, Hatch FS, Salvage SC, Orlowski A, Lampe PD, Fry CH. (2016) “Regulation of gap junction conductance by calcineurin through Cx43 phosphorylation: implications for action potential conduction.” Pflugers Arch 468(11-12):1945-1955. PMC5138272 2017

2015

  • Navarro, S.L., White, E., Kantor, E.D., Zhang, Y., Rho ,J., Song, X., Milne, G.L., Lampe, P.D., Lampe, J.W. (2015) Randomized trial of glucosamine and chondroitin supplementation on inflammation and oxidative stress biomarkers and plasma proteomics profiles in healthy humans. PloS one. 10(2):e0117534. PMCID: PMC4342228
  • Thomas, S.S., Makar, K.W., Li, L., Zheng, Y., Yang, P., Levy, L., Rudolph, R.Y., Lampe, P.D., Yan, M., Markowitz, S.D., Bigler, J., Lampe, J.W., Potter, J.D.(2015) Tissue-specific patterns of gene expression in the epithelium and stroma of normal colon in healthy individuals in an aspirin intervention trial. BMC medical genetics. 16(1):18. PMCID: PMC4422425
  • Mirus, J.E., Zhang ,Y., Li, C.I., Lokshin, A.E., Prentice, R.L., Hingorani, S.R., Lampe, P.D. (2015) Cross-species antibody microarray interrogation identifies a 3-protein panel of plasma biomarkers for early diagnosis of pancreas cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 21(7):1764-71. PMCID: PMC4391639
  • Shuhaibar, L.C., Egbert, J.R., Norris, R.P., Lampe, P.D., Nikolaev, V.O., Thunemann, M., Wen, L., Feil, R., Jaffe, L.A. (2015) Intercellular signaling via cyclic GMP diffusion through gap junctions restarts meiosis in mouse ovarian follicles. Proceedings of the National Academy of Sciences of the United States of America. 112(17):5527-32. PMCID: PMC4418852
  • Salas, D., Puebla, C., Lampe, P.D., Lavandero, S., Sáez, J.C5. (2015) Role of Akt and Ca(2+) on cell permeabilization via connexin43 hemichannels induced by metabolic inhibition. Biochimica et biophysica acta. 1852(7):1268-77. PMCID: PMC4476395
  • Johnson, R.G., Lampe, P.D., Laird, D.W. (2015) “Cellular Small Talk”. Scientific American, May issue, 70-77.
  • Schulz, R., Görge, P.M., Görbe, A., Ferdinandy, P., Lampe, P.D., Leybaert, L. (2015) “Connexin 43 is an emerging therapeutic target in ischemia/reperfusion injury, cardioprotection and neuroprotection” Pharm. Therapeud. 53:90-106. PMCID: PMC1783838
  • Meraviglia, M., Azzimato, V., Colussi, C., Florio, M.C., Binda, A., Panariti, A., Qanud, K., Suffredini, S., Gennaccaro, L., Miragoli, M., Barbuti, A., Lampe, P.D., Gaetano, C., Pramstaller, P.P., Capogrossi, M.C., Recchia, F.A., Pompilio, G., Rivolta, I., Rossini, A. (2015) “Acetylation mediates Cx43 reduction caused by electrical stimulation” J. Mol Cell Cardiology, 87:54-64. PMCID: PMC4637213
  • Buas MF, Rho JH, Chai X, Zhang Y, Lampe PD, Li CI. (2015) “Candidate early detection protein biomarkers for ER+/PR+ invasive ductal breast carcinoma identified using pre-clinical plasma from the WHI observational study”. Breast Cancer Res Treat. 153(2):445-54. PMCID: PMC4721565
  • Taguchi A, Rho JH, Yan Q, Zhang Y, Zhao Y, Xu H, Tripathi SC, Wang H, Brenner DE, Kucherlapati M, Kucherlapati R, Boutin AT, Wang YA, DePinho RA, Feng Z, Lampe PD, Hanash SM. (2015) “MAPRE1 as a Plasma Biomarker for Early-Stage Colorectal Cancer and Adenomas” Canc. Prev. Res. 8(11):1112-9. PMCID: PMC3419141
  • Riquelme MA, Burra S, Kar R, Lampe PD, Jiang JX. (2105) “Mitogen-activated Protein Kinase (MAPK) Activated by Prostaglandin E2 Phosphorylates Connexin 43 and Closes Osteocytic Hemichannels in Response to Continuous Flow Shear Stress.” J. Biol. Chem. 290(47):28321-8. PMCID: PMC4653687

2014

  • Brauer, H.A., D’Arcy, M., Libby, T.E., Thompson, H.J., Yasui, Y.Y., Hamajima, N., Li, C.I., Troester, M.A., Lampe, P.D. (2014) Dermcidin expression is associated with disease progression and survival among breast cancer patients Breast Cancer Research and Treatment.144(2):299-306. PMCID: PMC4403631
  • Dunn, C.A., Lampe, P.D. (2014) Injury-triggered Akt phosphorylation of Cx43: a ZO-1-driven molecular switch that regulates gap junction size. J. Cell Sci. 127, 455-464. Highlighted “In this Issue” Cx43 S373 phosphorylation – widening the gap. 127:e0203. PMCID: PMC3889401
  • Rho, J-H., Mead, J.R., Wright, W.S., Brenner, D.L., Stave, J.W., Gildersleeve, J., Lampe, P.D. (2014) Discovery of sialyl Lewis A and Lewis X modified protein cancer biomarkers using high density antibody arrays. J. Proteomics 96, 291–299. PMCID - PMC3946870
  • Rho, J-H., Lampe, P.D. (2014) High-throughput analysis of plasma hybrid markers for early detection of cancers. Proteomes, 2(1), 1-17.
  • Solan, J.L., Lampe, P.D. (2014) Specific Cx43 phosphorylation events regulate gap junction turnover in vivo.  FEBS Letters, PMCID - PMC3989505
  • Mirus, J.E., Zhang, Y., Hollingsworth, M.A., Solan, J.L., Lampe, P.D., Hingorani, S.R. (2014) Spatiotemporal proteomic analyses during pancreas cancer progression identifies serine/threonine stress kinase 4 (STK4) as a novel candidate biomarker for early stage disease. Molecular & cellular proteomics. 3(12):3484-96. PMCID: PMC4256499 [available 12-01-2015]
  • Ampey, B.C., Morschauser, T.J., Lampe, P.D., Magness, R.R. (2014) Gap Junction Regulation of Vascular Tone: Implications of Modulatory Intercellular Communication during Gestation in "40th Anniversary of The Center for Perinatal Biology, Springer, New York. doi: 10.1007/978-1-4939-1031-1_11
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2013

  • Chen, S. C., Kennedy, B.K., Lampe, P.D. (2013) “Phosphorylation of connexin43 on S279/282 may contribute to laminopathy-associated conduction defects” Exper. Cell Res. 319(6):888-96. PMCID: PMC3594536
  •  Li, D., Sekhon, P., Barr, K.J., Márquez-Rosado, L., Lampe, P.D., and Kidder, G.M. (2013) Connexins and steroidogenesis in mouse Leydig cells. Can. J. Physiol. Pharmacol. 91(2):157-64. PMCID: PMC3624991
  •  Rho, J-H., Lampe, P.D., (2013) High-throughput screening for native autoantigen-autoantibody complexes using antibody microarrays. J. Proteome Res. 12(5):2311-20. PMCID: PMC3680356.
  • Sakurai, T., Tsuchida M., Lampe, P.D., Murakami, M. (2013) Cardiomyocyte FGF signaling is required for Cx43 phosphorylation and cardiac tissue maintenance Exper. Cell Res. 319(14):2152-65. PMCID: PMC3783259.
  •  Xu, Q., Lin, X., Andrews, L., Patel, D., Lampe, P.D., Veenstra, R.D. (2013) Histone deacetylase inhibition reduces cardiac connexin43 expression and gap junction communication. Front Pharmacol. 4:44. PMCID: PMC3625725.

2012

  • Amon, L.M., Pitteri, S.J., Li, C.I., McIntosh, M., Ladd, J. Disis, M. Porter, P. Wong, C-H Zhang, Q., Lampe, P.D., Prentice, R.L., Hanash, S.M. (2012) Concordant release of glycolysis proteins into the plasma preceding a diagnosis of ER+ breast cancer.  Cancer Research, 72(8):1935-42.
  • Dunn, C.A., Su, V, Lau, A.F. and Lampe, P.D. (2012) Activation of Akt, not Connexin43 ubiquitination, regulates gap junction stability. J. Biol. Chem., 287(4):2600-7. PMCID: PMC3268419
  • Dyce, P.W., Norris, R.P., Lampe, P.D., Kidder, G.M. (2012) Phosphorylation of Serine Residues in the C-terminal Cytoplasmic Tail of Connexin43 Regulates Proliferation of Ovarian Granulosa Cells. Journal of Membrane Biology, 245(5-6), 291-301. PMCID: PMC3578320.
  • Johnstone SR, Kroncke BM, Straub AC, Best AK, Dunn CA, Mitchell LA, Peskova Y, Nakamoto RK, Koval M, Lo CW, Lampe PD, Columbus L, Isakson BE. (2012) MAPK phosphorylation of connexin 43 promotes binding of cyclin E and smooth muscle cell proliferation. Circ Res. 111(2):201-11.  PMCID: PMC3405546
  • Ladd, J. Buson, T.B., Johnson, M.M., Zhang, Q., Pitteri, S.J., Wang, H., Brenner, D. Lampe, P.D., Feng, Z., Prentice, R.L. and Hanash, S. (2012) Increased plasma levels of the APC-interacting protein MAPRE1, LRG1 and IGFBP2 preceding a diagnosis of colorectal cancer. Cancer Prev Res. 4, 655-64. PMCID: PMC3419141
  • Lampe, P.D., Laird, D.W. Introduction paper of the special issue on gap junctions in honor of Ross Johnson. (2012) J Membr Biol. 245(5-6):217-9.
  • Li, C.I., Mirus, J.E., Zhang, Y., Ramirez, A.B., Ladd, J.J., Prentice, R.L., McIntosh, M., Hanash, S.M., Lampe, P.D. (2012) Discovery and preliminary validation of novel early detection biomarkers for triple-negative breast cancer using preclinical plasma samples from the Women’s Health Initiative observational study. Breast Cancer Res Treat. 2012 Sep;135(2):611-8. PMCID: PMC3439142
  • Márquez-Rosado, L., Singh, D., Rincón-Arano, H., Solan, J.L., Lampe, P.D. (2012) CASK/LIN-2 interacts with Cx43 in wounded skin and their co-expression affects cell migration. J. Cell Sci., 125(Pt 3):695-702. PMCID: PMC3367831
  • Solan, J.L., Hingorani, S.R., Lampe, P.D.  (2012) Changes in connexin43 expression and localization during pancreatic cancer progression. Journal of Membrane Biology, 245(5-6), 255-62. PMCID: PMC3518378

2011

  • Brauer, H.A., Libby, T.E., Mitchell, B.L., Li, L., Chen, C., Randolph, T.W., Yasui, Y.Y., Lampe, J.W., Lampe, P.D.  (2011) Cruciferous vegetable supplementation in a controlled diet study alters the serum peptidome in a GSTM1-genotype dependent manner. Nutrition Journal, 10, 11, 1-11. PMCID: PMC3042379.
  • Huang, G-Y., Xie, L-J., Linask, K.L., Zhang, C., Zhao, X-Q., Zhao, X-Q., Yang, Y., Zhou, G-M., Wu, Y-J., Marquez-Rosado, L., McElhinney, D.B, Goldmuntz, E., Liu, C., Lampe, P.D., Chatterjee, B., Lo, C.W.  (2011) Evaluating the role of connexin43 in congenital heart disease: Screening for mutations in patients with outflow tract anomalies and the analysis of knockin mouse models. J. Cardiovasc. Dis. Res., 2(4), 206-12. PMCID: PMC3224440
  • Márquez-Rosado, L., Solan, J.L., Dunn, C.A., Norris, R.P. and Lampe, P.D. (2011) Connexin43 phosphorylation in brain, cardiac, endothelial and epithelial tissues. Biochim Biophys Acta – Biomembranes, 2011 Jul 26. [Epub ahead of print] PMID: 21819962. PMCID: PMC3241956
  • Ramirez, A.B. Lampe, P.D. (2011) Discovery and Validation of Ovarian Cancer Biomarkers Utilizing High Density Antibody Microarrays. Cancer Biomarkers, 8 (4/5), p293-307.
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2010

  • Boassa, D., Solan, J.L., Papas, A., Thornton, P., Lampe, P.D., Sosinsky, G. (2010) Trafficking and Recycling of the Connexin43 Gap Junction Protein during Mitosis.  Traffic, 11, 1471-1486. PMCID: PMC3272544.
  • Brauer, H.A, Lampe, P.D., Yasui, Y.Y., Hamajima, N.N., Stolowitz, M.L. (2010) Biochips that Sequentially Capture and Focus Antigens for Immunoaffinity MALDI-TOF MS: A New Tool for Biomarker Verification. Proteomics 10 (21), 3922-7. PMCID: PMC3046459
  • del Castillo, F.J., Cohen-Salmon, M., Charollais, A., Caille, D., Lampe, P.D., Chavrier, Meda, P., Petit, C. (2010)  Consortin, a trans-golgi network cargo receptor for the plasma membrane targeting and recycling of connexions.  Human Mol Genetics, 19 (2):262-75. PMCID: PMC2796891
  • Pitteri, P., Amon, L., Busald Buson, T., Zhang, Y., Johnson, M., Chin, A., Kennedy, J., Wong, C.-H., Zhang, Q, Wang, H., Lampe, P.D., Prentice, P., McIntosh, M., Hanash, S., Li, C.I. (2010) Elevated Plasma Levels of Epidermal Growth Factor Receptor Prior to Diagnosis of Breast Cancer among Hormone Therapy Users. Cancer Research, 70 (21) 8598-8606. PMCID: PMC2970770.
  • Ramirez, A.B., Loch, C.M., Zhang, Y., Liu, Y., Wang, X., Wayner, E.A., Sargent, J., Sibani, S., Mendoza, E.A., Eugene, R., LaBaer, J., Urban, N. McIntosh, M.W., Lampe, P.D. (2010)  Use of a single chain antibody library for ovarian cancer biomarker discovery. Molecular and Cellular Proteomics, 9 (7), 1449-1460. Highlighted in ASBMB today, “Biobits”, p. 33, July 2010.  PMCID: PMC2938096

2009

  • Actis, A.B., Cremonezzi, D.C., Lampe, P.D., Carino, S., Valentich, M.A. (2009) Dietary lipids change the expression of a proliferation marker in murine 9,10-dimethyl-1,2-benzanthracene-induced salivary tumors J. Food Lipids 16, 314-324.
  • Johnstone, S.R., Ross, J, Rizzo, MJ, Straub, A., Lampe, P.D., Leitinger, N., Isakson, B.E. (2009) Oxidized phospholipid species promote in vivo differential Cx43 phosphorylation and vascular smooth muscle cell proliferation. Amer. J. Pathol. 175(2):916-24. PMCID: PMC2716985
  • Sin, W-C, Tse, M, Planque, N, Perbal, B, Lampe, P.D., Naus, C.C. (2009) Matricellular protein CCN3 regulates actin cytoskeleton reorganization. J. Biol. Chem. 284(43):29935-44. PMCID: PMC2785622
  • Solan, J.L., Lampe, P.D. (2009) Connexin43 Phosphorylation: Structural Changes And Biological Effects.  Biochemical Journal 419(2), 261-72. PMCID: PMC2669545

2008

  • Adewale, A. Liu, Q., Dinu, I., Lampe, P.D., Mitchell, B.L., Yasui, Y. (2008) A Cautionary Note on the Evaluation of Biomarkers of Subtypes of a Single Disease.   Amer. J. Epidemiol. 68(6), 559-62. PMCID: PMC3139966
  • Norris, R.P., Freudzon, M., Mehlmann, L.M. Cowan, A.E., Simon, A.M., Paul, D.L., Lampe, P.D., (co-corresponding author) Jaffe, L.A. (2008) Luteinizing hormone causes MAP kinase-dependent phosphorylation and closure of Cx43 gap junctions in mouse ovarian follicles: one of two paths to meiotic resumption.  Development. 135, 3329-3238.  Highlighted “In this issue” 135(19). PMCID: PMC2572224
  • Qu, J., Volpicelli, F.M., Garcia, L.I., Sandeep, N., Márquez-Rosado, L., Lampe, P.D., Fishman, G.I.  (2008) Gap junction remodeling and spironolactone-dependent reverse remodeling in the hypertrophied heart. Circulation Research 104(3):365-71. PMCID: PMC2652889
  • Scholler N, Gross JA, Garvik B, Wells L, Liu Y, Loch CM, Ramirez AB, McIntosh MW, Lampe PD, Urban N (2008) Use of cancer-specific yeast-secreted in vivo biotinylated recombinant antibodies for serum biomarker discovery., Journal of translational medicine, 6:41. PMCID: PMC2503970.
    http://www.translational-medicine.com/content/6/1/41
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2007

  • Solan JL, Marquez-Rosado L, Sorgen PL, Thornton PJ, Gafken PR, Lampe PD (2007) Phosphorylation at S365 is a gatekeeper event that changes the structure of Cx43 and prevents down-regulation by PKC, Journal of Cell Biology, 179(3)1301-1309. PMCID: PMC2140020
  • Loch CM, Ramirez AB, Liu Y, Sather CL, Delrow JJ, Scholler N, Garvik BM, Urban ND, McIntosh MW, Lampe PD (Dec 2007) Use of High Density Antibody Arrays to Validate and Discover Cancer Serum Biomarkers, Molecular Oncology, 1(3)313-20. PMCID: PMC2671017
  • Sosinsky GE, Solan JL, Gaietta GM, Ngan L, Lee GJ, Mackey MR, Lampe PD (Dec 2007) The C-terminus of connexin43 adopts different conformations in the Golgi and gap junction as detected with structure-specific antibodies., The Biochemical Journal, 408(3)375-85. PMCID: PMC2267357
  • Abrahamson PE, King IB, Ulrich CM, Rudolph RE, Irwin ML, Yasui Y, Surawicz C, Lampe JW, Lampe PD, Morgan A, Sorensen BE, Ayub K, Potter JD, McTiernan A (Nov 2007) No effect of exercise on colon mucosal prostaglandin concentrations: a 12-month randomized controlled trial., Cancer epidemiology, biomarkers & prevention, 16(11)2351-6.  
  • Campbell KL, McTiernan A, Li SS, Sorensen BE, Yasui Y, Lampe JW, King IB, Ulrich CM, Rudolph RE, Irwin ML, Surawicz C, Ayub K, Potter JD, Lampe PD (Sep 2007) Effect of a 12-month exercise intervention on the apoptotic regulating proteins Bax and Bcl-2 in colon crypts: a randomized controlled trial., Cancer epidemiology, biomarkers & prevention, 16(9)1767-74
  • McTiernan A, Sorensen B, Irwin ML, Morgan A, Yasui Y, Rudolph RE, Surawicz C, Lampe JW, Lampe PD, Ayub K, Potter JD (Jun 2007) Exercise effect on weight and body fat in men and women., Obesity, 15(6)1496-512
  • Solan JL, Lampe PD (Jun 2007) Key connexin 43 phosphorylation events regulate the gap junction life cycle., The Journal of membrane biology, 217(1-3)35-41. PMCID: PMC2596931
  • McTiernan, A, Yasui, Y, Sorensen, B, Irwin, ML, Morgan, A, Rudolph, RE, Surawicz, C, Lampe, JW, Ayub, K, Potter, JD, Lampe, PD (2007) Effect of a 12-month exercise intervention on patterns of cellular proliferation in colonic crypts: a randomized controlled trial, Cancer Epidemiology, Biomarkers & Prevention, 15, 1588-1597.

2006

  • Gafken, PR, Lampe, PD (2006) Methodologies for Characterizing Phosphoproteins by Mass Spectrometry, Cell Communication and Adhesion, 13, 249-262
  • McTiernan A, Yasui Y, Sorensen B, Irwin ML, Morgan A, Rudolph RE, Surawicz C, Lampe JW, Ayub K, Potter JD, Lampe PD (Sep 2006) Effect of a 12-month exercise intervention on patterns of cellular proliferation in colonic crypts: a randomized controlled trial., Cancer epidemiology, biomarkers & prevention, 15(9)1588-97
  • Lampe, PD, Cooper, CD, King, TJ, Burt, JM (2006) Analysis of Phosphorylation of Connexin43 at S325/328/330 in Normoxic and Ischemic Heart, Journal of Cell Science, 119, 3435-42
  • Ek-Vitorin, JF, King, TJ, Heyman, NS, Lampe, PD, Burt, JM (2006) Selectivity of Cx43 channels is regulated through PKC-dependent phosphorylation, Circulation Research, 98, 1498-1505

2005

  • King, TJ, Lampe, PD (Dec 2005) Temporal Regulation of Connexin Phosphorlation in Embryonic and Adult Tissues, Biochimica Biophysica Acta- Biomembranes, 1719(1)24-35
  • Randolph, TW, Mitchell, BL, McLerran, D, Lampe, PD, Feng, Z (Sept 29, 2005) Quantifying Peptide Signal in MALDI-TOF Mass Spectrometry Data, Molecular and Cellular Proteomics, 4, 1990-1999
  • Singh D, Solan JL, Taffet SM, Javier R, Lampe PD (Aug 2005) Connexin 43 interacts with zona occludens-1 and -2 proteins in a cell cycle stage-specific manner., The Journal of Biological Chemistry, 280(34)30416-21
  • Solan JL, Lampe PD (Jun 2005) Connexin phosphorylation as a regulatory event linked to gap junction, Biochimica Biophysica Acta, 1711(2)154-63
  • Mitchell BL, Yasui Y, Lampe JW, Gafken PR, Lampe PD (May 2005) Evaluation of matrix-assisted laser desorption/ionization-time of flight mass spectrometry proteomic profiling: identification of alpha 2-HS glycoprotein B-chain as a biomarker of diet., Proteomics, 5(8)2238-46
  • King TJ, Gurley KE, Prunty J, Shin JL, Kemp CJ, Lampe PD, Deficiency in the Gap Junction Protein Connexin32 Alters P27Kip1 Tumor Suppression and MAPK Activation in a Tissue-specific Manner, Oncogene, 24(10):1718-26, Mar 2005
  • Rudolph RE, Dominitz JA, Lampe JW, Levy L, Qu P, Li SS, Lampe PD, Bronner MP, Potter JD (Mar 2005) Risk factors for colorectal cancer in relation to number and size of aberrant crypt foci in humans., Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology., 14(3)605-8
  • Mitchell, BL, Yasui, Y, Li, CI, Fitzpatrick, AL, Lampe, PD, Impact of Freeze-thaw Cycles and Storage Time on Plasma Samples Used in Mass Spectrometry Based Biomarker Discovery Projects, Cancer Informatics, 1(1):25-31, Jan 2005
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2004

  • Richards TS, Dunn CA, Carter WG, Usui ML, Olerud JE, Lampe PD (Nov 2004) Protein kinase C spatially and temporally regulates gap junctional communication during human wound repair via phosphorylation of connexin43 on serine368, The Journal of Cell Biology, 167(3)555-62
  • King TJ, Lampe PD (Oct 2004) The gap junction protein connexin32 is a mouse lung tumor suppressor., Cancer Research, 64(20)7191-6
  • Lampe PD, Lau AF (Jul 2004) The effects of connexin phosphorylation on gap junctional communication., The International Journal of Biochemistry & Cell Biology, 36(7)1171-86
  • King TJ, Lampe PD (May 2004) Mice deficient for the gap junction protein Connexin32 exhibit increased radiation-induced tumorigenesis associated with elevated mitogen-activated protein kinase (p44/Erk1, p42/Erk2) activation., Carcinogenesis, 25(5)669-80

2003

  • Solan JL, Fry MD, TenBroek EM, Lampe PD (June 2003) Connexin43 phosphorylation at S368 is acute during S and G2/M and in response to protein kinase C activation, Journal of Cell Science, 116(Pt 11)2203-11
  • Lampe P, Beyer E, New developments in the gap junction field: report from the 2002 ASCB meeting, Cell Communication & Adhesion, 10(1):55-8, Jan-F 2003
  • Singh D, Lampe PD (Jul-Dec 2003) Identification of connexin-43 interacting proteins., Cell Communication & Adhesion, 10(4-6)215-20

2002

  • Cooper CD, Lampe PD (Nov 2002) Casein kinase 1 regulates connexin-43 gap junction assembly., The Journal of Biological Chemistry, 277(47)44962-8
  • King TJ, Fukushima LH, Yasui Y, Lampe PD, Bertram JS, Inducible expression of the gap junction protein connexin43 decreases the neoplastic potential of HT-1080 human fibrosarcoma cells in vitro and in vivo, Molecular Carcinogenesis, 35(1):29-41, September 2002
  • Goldberg GS, Moreno AP, Lampe PD (September 2002) Gap junctions between cells expressing connexin 43 or 32 show inverse permselectivity to adenosine and ATP, Journal of Biological Chemistry, 277(39)36725-30
  • Actis AB, Lampe PD, Eynard AR, Cellular basis and clinical implications of biological markers in salivary tissues: their topological distribution in murine submandibular gland, Oral Oncology, 38(5):441-9, July 2002
  • Chu G, Carr AN, Young KB, Lester JW, Yatani A, Sanbe A, Colbert MC, Schwartz SM, Frank KF, Lampe PD, Robbins J, Molkentin JD, Kranias EG, Enhanced myocyte contractility and Ca2+ handling in a calcineurin transgenic model of heart failure, Cardiovascular Research, 54(1):105-16, April 2002
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2001

  • TenBroek EM, Lampe PD, Solan JL, Reynhout JK, Johnson RG (December 2001) Ser364 of connexin43 and the upregulation of gap junction assembly by cAMP, Journal of Cell Biology, 155(7)1307-18
  • Lampe PD, Qiu Q, Meyer RA, TenBroek EM, Walseth TF, Starich TA, Grunenwald HL, Johnson RG (October 2001) Gap junction assembly: PTX-sensitive G proteins regulate the distribution of connexin43 within cells, American Journal of Physiology. Cell Physiology, 281(4)C1211-22
  • Shin JL, Solan JL, Lampe PD, The regulatory role of the C-terminal domain of connexin43, Cell Adhesion and Communication, 8(4-6):271-5, 2001
  • Goldberg GS, Lampe PD (2001) Capture of transjunctional metabolites., Methods in Molecular Biology (clifton, N.j.), 154, 329-40

2000

  • Lampe PD, Lau AF (Dec 2000) Regulation of gap junctions by phosphorylation of connexins., Archives of Biochemistry and Biophysics, 384(2)205-15
  • Paulson AF, Lampe PD, Meyer RA, TenBroek E, Atkinson MM, Walseth TF, Johnson RG (September 2000) Cyclic AMP and LDL trigger a rapid enhancement in gap junction assembly through a stimulation of connexin trafficking, Journal of Cell Science, 113 ( Pt 17), 3037-49
  • Lampe PD, TenBroek EM, Burt JM, Kurata WE, Johnson RG, Lau AF (June 2000) Phosphorylation of connexin43 on serine368 by protein kinase C regulates gap junctional communication, Journal of Cell Biology, 149(7)1503-12
  • Bukauskas FF, Jordan K, Bukauskiene A, Bennett MV, Lampe PD, Laird DW, Verselis VK, Clustering of connexin 43-enhanced green fluorescent protein gap junction channels and functional coupling in living cells, Proceedings of the National Academy of Sciences (USA), 97(6):2556-61, March 2000
  • Cooper CD, Solan JL, Dolejsi MK, Lampe PD, Analysis of connexin phosphorylation sites, Methods, 20(2):196-204, February 2000

1999 – 1995

  • Goldberg GS, Lampe PD, Nicholson BJ, Selective transfer of endogenous metabolites through gap junctions composed of different connexins, Nature Cell Biology, 1(7):457-9, November 1999
  • Jordan K, Solan JL, Dominguez M, Sia M, Hand A, Lampe PD, Laird DW, Trafficking, assembly, and function of a connexin43-green fluorescent protein chimera in live mammalian cells, Molecular Biology of the Cell, 10(6):2033-50, June 1999
  • Lampe PD Beyer EC, Gap Junctions, Trends in Cell Biology, 9, 119, March 1999
  • Lampe PD, Nguyen BP, Gil S, Usui M, Olerud J, Takada Y, Carter WG (December 1998) Cellular interaction of integrin alpha3beta1 with laminin 5 promotes gap junctional communication, Journal of Cell Biology, 143(6)1735-47
  • Lampe PD, Kurata WE, Warn-Cramer BJ, Lau AF (March 1998) Formation of a distinct connexin43 phosphoisoform in mitotic cells is dependent upon p34cdc2 kinase, Journal of Cell Science, 111 ( Pt 6), 833-41
  • Goldberg GS, Lampe PD, Sheedy D, Stewart CC, Nicholson BJ, Naus CC, Direct isolation and analysis of endogenous transjunctional ADP from Cx43 transfected C6 glioma cells, Experimental Cell Research, 239(1):82-92, February 1998
  • Berthoud VM, Beyer EC, Kurata WE, Lau AF, Lampe PD (February 1997) The gap-junction protein connexin 56 is phosphorylated in the intracellular loop and the carboxy-terminal region, European Journal of Biochemistry, 244(1)89-97
  • Modesto E, Lampe PD, Ribeiro MC, Spray DC, Campos de Carvalho AC (December 1996) Properties of chicken lens MIP channels reconstituted into planar lipid bilayers, Journal of Membrane Biology, 154(3)239-49
  • Baumann CG, Malewicz B, Anderson WH, Lampe PD, Johnson RG, Baumann WJ, Lipid differentiation in MP26 junction enriched membranes of bovine lens fiber cells, Biochimica Et Biophysica Acta, 1303(2):145-53, September 1996
  • Lau AF, Kurata WE, Kanemitsu MY, Loo LW, Warn-Cramer BJ, Eckhart W, Lampe PD (August 1996) Regulation of connexin43 function by activated tyrosine protein kinases, Journal of Bioenergetics and Biomembranes, 28(4)359-68
  • Li H, Liu TF, Lazrak A, Peracchia C, Goldberg GS, Lampe PD, Johnson RG (August 1996) Properties and regulation of gap junctional hemichannels in the plasma membranes of cultured cells, Journal of Cell Biology, 134(4)1019-30
  • Warn-Cramer BJ, Lampe PD, Kurata WE, Kanemitsu MY, Loo LW, Eckhart W, Lau AF (February 1996) Characterization of the mitogen-activated protein kinase phosphorylation sites on the connexin-43 gap junction protein, Journal of Biological Chemistry, 271(7)3779-86
  • Atkinson MM, Lampe PD, Lin HH, Kollander R, Li XR, Kiang DT (September 1995) Cyclic AMP modifies the cellular distribution of connexin43 and induces a persistent increase in the junctional permeability of mouse mammary tumor cells, Journal of Cell Science, 108 ( Pt 9), 3079-90
  • Darrow BJ, Laing JG, Lampe PD, Saffitz JE, Beyer EC (March 1995), Expression of multiple connexins in cultured neonatal rat ventricular myocytes, Circulation Research, 76(3):381-7
  • Lampe PD (Dec 1994) Analyzing phorbol ester effects on gap junctional communication: a dramatic inhibition of assembly., The Journal of Cell Biology, 127(6 Pt 2)1895-905
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