Lab Members

Jim Kublin, MD, MPH

Jim Kublin, MD, MPH

Title: Principal Investigator
Phone: 206.667.1970

Executive Director, HIV Vaccine Trials Network (HVTN)
Medical Director, Seattle Malaria Clinical Trials Center (Seattle MCTC)
Principal Staff Scientist, Vaccine and Infectious Disease Division (Fred Hutch)
Clinical Associate Professor, Global Health (UW)

Research Interests:

  • HIV and tuberculosis (Tb) vaccine research and development
  • Human challenge experiments
  • Microbiome modulation of immunity
  • Immune activation—polymicrobial infections
  • Combination HIV prevention
  • Malaria clinical trials/vaccines
  • Molecular epidemiology
Kevin Hager, MS

Kevin Hager, MS

Title: Research Technician
Phone: 206.667.6334

Research Interests: 

  • Microbial ecology and community structure and function of gut ecosystems
  • The relationship between gut microbes and their host
  • The influence of commensal gut bacteria on host health and vaccine response

 

Andrew Johnson, PhD

Andrew Johnson, PhD

Title: Staff Scientist
Phone: 206.667.3689
Location: E3-141

Research Interests: 

  • Intestinal and systemic immune responses
  • Host-microbe interactions
  • Early life conditioning of the immune system
  • Data science tools to integrate microbiome data with patient metadata to predict treatment efficacy
Phuong Van, BS

Phuong Van, BS

Title: Research Technician
Phone: 206.667.3614

Research Interests: 

  • The effect of microbiome on vaccine efficacy and metabolism of treatment
  • How host-genetics and environmental factors modulates the microbiome and immune system
  • Characterizing the crosstalk between immune system and gut microbes
Andy King, PhD

Andy King, PhD

Title: Post-Doctoral Research Fellow
Phone: 206.667.7592
Location: E3-154D

Research Interests: 

  • Prediction of immune response to vaccines / infections based on composition of the microbiota
  • How local host-microbe interactions (e.g. in the gut) affect the behavior of the immune system at large
  • The influence of the microbiota on immune tolerance / activation
Nicole Potchen, BS

Nicole Potchen, BS

Title: PhD Candidate (Pathobiology - UW)
Phone: 206.667.6594

Research Interests: 

  •  Cross reactive antibodies against the gut microbiome and HIV 
  • Environmental or genetic factors that impact immune function 
  • Diseases of global health importance
Sue Ferguson

Sue Ferguson

Title: Project Manager, HIV Vaccine Trials Network (HVTN)
Phone: 206.667.1296

Collaborators

Andrew Fiore-Gartland, PhD

Andrew Fiore-Gartland, PhD

Title: Staff Scientist, BBE Faculty & Faculty Staff

Research interests:

  • Role of gut microbiome in population vaccine response heterogeneity
  • Immune correlates of protection in vaccine efficacy trials
  • T cell clonal diversity and cross-reactivity
  • Innate predictors of vaccine immunogenicity
  • Immunologically-informed sieve analysis
  • Determinants of immunodominance
  • Host-genetics and vaccine efficacy

 

Sam Minot, PhD

Sam Minot, PhD

Title: Staff Scientist, Fredricks Lab

Research interests: 

  • Functional metagenomic analysis of the human microbiome
  • Impact of the microbiome on chemotherapeutic efficacy and vaccine response
  • Role of strain-level microbial diversity influencing common human diseases

Alumni

Jacob Cram, PhD

Jacob Cram, PhD

Title: Postdoctoral Research Fellow

Research interests:

  • Microbial community ecology
    Understanding how microorganisms are affected by and in term shape their environment, such as the human host or marine environments
  • Examining how microorganisms shape the human immune systems’ response to vaccines
  • Using computational tools, statistics, and modeling to illuminate microbiome-environment interactions.

 

Vessel sculpture and Arnold Building on Fred Hutch campus

Tobi A. Akingbade, MPH

Title: Project Coordinator, Kublin Lab / Seattle Malaria Clinical Trials Center
Phone: 206.667.2306
Mark Fernandez, BS

Mark Fernandez, BS

Title: Graduate Rotation Student (Pathobiology - UW)
Email: markf2@uw.edu

Research Interests:

  • Vaccine development, especially in the context of using vaccines to combat the rising tide of antibiotic resistance.
  • Mechanisms of bacterial pathogenesis
  • Immune evasion strategies pathogens use to subvert host defenses

 

Meera Shenoy, PhD

Meera Shenoy, PhD

Title: Postdoctoral Research Fellow

Research Interests:

  • Role of the microbiome in determining vaccine efficacy
  • Host-microbe interactions at the mucosal surface and their influence on systemic immunity
  • Effects of microbe-microbe interactions and metabolism on host physiology
  • Understanding innate and innate-like subset interactions with commensal microbial communities