Selected publications sorted by methodology and collaboration.


Dai JY, Tapsoba JDT, Buas MF, the BEACON Consortium, Risch H, Vaughan TL. Constrained score statistics identify genetic loci interacting with multiple risk factors in Barrett’s esophagus. American Journal of Human Genetics: 2016. 99(2):352-65.

Cheng Y, Dai JY, Kooperberg C. Group association test using hidden Markov models. Biostatistics. 2016: 17(2):221-234.

Dai JY, Zhang X, Wang CY, Kooperberg C. Augmented case-only design for randomized clinical trials with failure time endpoints. Biometrics. 2016; 72(1):30-8.

Dai JY, Zhang X. Mendelian randomization studies for a continuous exposure under case-control sampling. American Journal of Epidemiology. 2015;181(6):440-449.

Dai JY, Chan KC, Hsu L. Testing concordance of instrumental variable effects in generalized linear models with application to Mendelian randomization. Statistics in Medicine. 2014; 33(23):3986-4007.

Tapsoba JD, Kooperberg C, Reiner AP, Wang CY, Dai JY. Robust estimation for secondary trait association in case-control genetic studies. American Journal of Epidemiology. 2014;179(10):1264-72.

Dai JY, Li SS, Gilbert PB. Case-only methods for competing risks models with application to assessing differential vaccine efficacy by viral and host genetics. Biostatistics. 2014; 15(1):196-203.

Dai JY, Gilbert PB, Hughes JP, Brown E. Estimating PrEP efficacy for HIV prevention among participants with a threshold level of drug concentration. American Journal of Epidemiology. 2013; 177(3):256-263.

Dai JY, Kooperberg C, LeBlanc M, Prentice RL. Two-stage testing procedures with independent filtering for genome-wide gene-environment interaction. Biometrika. 2012; 99(4):929-944.

Dai JY, Hughes JP. A unified procedure for meta-analytic evaluation of surrogate endpoints in randomized clinical trials. Biostatistics. 2012;13(4):609-624.

Hsu L, Jiao So J, Dai JY, Hutter CM, Peters U, Kooperberg C. Powerful cocktail methods for detecting genome-wide gene-environment interaction. Genetic Epidemiology. 2012;36:183-194.

Dai JY, Logsdon B, Huang Y, Hsu L, Reiner A, Prentice R, Kooperberg C. Simultaneously testing for marginal genetic association and gene-environment interaction. American Journal of Epidemiology. 2012;176:164-173.

Dai JY, Gilbert PB, Masse BR. Partially hidden Markov model for time-varying principal stratification in HIV prevention trials. Journal of American Statistical Association. 2012;107:52-65.

Lumley T, Shaw PA, Dai JY. Connections between Survey Calibration Estimators and Semiparametric Models for Incomplete Data. International Statistical Review. 2011; 79(2):200-20.

Kooperberg C, LeBlanc M, Dai JY, Rajapakse I. Structures and Assumptions: Strategies to Harness Gene x Gene and Gene x Environment Interactions in GWAS. Statistical Science. 2009; 24(4):472-88.

Dai JY, LeBlanc M, Smith NL, Psaty B, Kooperberg C. SHARE: an adaptive algorithm to select the most informative set of SNPs for candidate genetic association. Biostatistics. 2009; 10(4):680-93.

Dai JY, LeBlanc M, Kooperberg C. Semiparametric estimation exploiting covariate independence in two-phase randomized trials. Biometrics. 2009; 65(1):178-87.

Storey JD, Dai JY, Leek JT. The optimal discovery procedure for large-scale significance testing, with applications to comparative microarray experiments. Biostatistics. 2007; 8(2):414-32.

Dai JY, Ruczinski I, LeBlanc M, Kooperberg C. Imputation methods to improve inference in SNP association studies. Genetic Epidemiology. 2006; 30(8):690-702.



Dai JY, Hendrix C, Richardson B, Cliff K, Marzinke M, Chirenje M, Marrazzo J, Brown ER.  Pharmacological measures of adherence and risk of HIV acquisition in the VOICE study. Journal of Infectious Diseases. 2016;213(3):335-42 .

Wang X, Li X, Paulson TG, Reid BJ, Kooperberg C, Dai JY. Copy number alterations detected by whole-exome and whole-genome sequencing of esophageal adenocarcinoma. Human Genomics. 2015: 9:22; DOI: 10.1186/s40246-015-0044-0.

Dai JY, Tapsoba JDT, Buas MF, Onstad L, Levine DM, Risch HA, Chow WH, Bernstein L, Ye W, Lagergren J, Bird NC, Corley DA, Shaheen NJ, Wu AH, Hardie LJ, Reid BJ, Whiteman DC, Vaughan TL. A newly identified susceptibility locus near FOXP1 modifies the association of gastroesophageal reflux with Barrett’s esophagus. Cancer Epidemiology, Biomarker & Prevention. 2015; 24(11):1739-47.

Marrazzo JM, Ramjee G, Richardson BA, Gomez K, Mgodi N, Nair G, Palanee T, Nakabiito C, van der Straten A, Noguchi L, Hendrix CW, Dai JY, Ganesh S, Mkhize B, Taljaard M, Parikh UM, Piper J, Masse B, Grossman C, Rooney J, Schwartz JL, Watts H, Marzinke MA, Hillier SL, McGowan IM, Chirenje ZM, for the VOICE Study Team. Tenofovir-Based preexposure prophylaxis for HIV infection among African women. New England Journal of Medicine. 2015;372(6):509-18.

Liu S, Dai JY, Yao L, Li X, Reid B, Self S, Ma J, Chang Y, Feng S, Tapsoba JD, Sun X, Sun XB. Esophageal adenocarcinoma and its rare association with Barrett's esophagus in Henan, China. PLoS ONE. 2014; DOI: 10.1371/journal.pone.0110348.

Li SS, Gilbert PB, Tomaras GD, Kijak G, Ferrari G, Thomas R, Zolla-Pazner S, Montefiori D, Liao X, Nabel G, Pinter A, Evans DT, Gottardo R, Dai JY, Janes H, Morris D, Fong Y, Edlefsen PT, Li F, Frahm N, Alpert MD, Rerks-Ngarm S, Pitisuttithum P, Kaewkungwal J, Nitayaphan S, Robb ML, O'Connell RJ, Haynes BF, Michael NL, Kim JH, McElrath MJ, Geraghty D. Association of a FCGR2C polymorphism with vaccine efficacy and correlates of HIV-1 infection risk in the RV144 trial. Journal of Clinical Investigation. 2014;124(9):3879-3890.

McGowan I, Hoesley C, Cranston RD, Andrew P, Janocko L, Dai JY, Carballo-Dieguez A, Kunjara Na Ayudhya R, Piper J, Hladik F, Mayer K.  A Phase 1 Randomized, Double Blind, Placebo Controlled Rectal Safety and Acceptability Study of Tenofovir 1% gel (MTN-007).  PLoS One. 2013;8(4) :e60147.

Huang Y, Ballinger DG, Dai JY, Peters U, Hinds DA, Cox DR, Beilharz E, Chlebowski RT, Rossouw JE, McTiernan A, Rohan T, Prentice RL. Genetic variants in the MRPS30 region and postmenopausal breast cancer risk. Genome Medicine. 2011; 3(6):42.

Reid SE, Dai JY, Wang J, Sichalwe BN, Akpomiemie G, Cowan FM, Delany-Moretlwe S, Baeten JM, Hughes JP, Wald A, Celum C. Pregnancy, contraceptive use, and HIV acquisition in HPTN 039: relevance for HIV prevention trials among African women. Journal of Acquired Immune Deficiency Syndromes. 2010; 53(5):606-13.

Dai JY, DeFrances MC, Zou C, Johnson CJ, Zarnegar R. The Met protooncogene is a transcriptional target of NF kappaB: implications for cell survival. Journal of Cellular Biochemistry. 2009; 107(6):1222-36.

Eberly LE, Neaton JD, Thomas AJ, Dai Y. Multiple-stage screening and mortality in the Multiple Risk Factor Intervention Trial. Journal of the Society for Clinical Trials. 2004; 1(2):148-61.