Hatch Lab

Hatch Lab

Fluorescent image of lung tumor section

Fluorescent image of lung tumor section

Our Research

Welcome to the Hatch Lab. Our lab studies the organization and dynamics of the nuclear envelope to understand how changes in this structure cause human genetic diseases and drive cancer development. Our current focus is the mechanisms and consequences of a recently described dynamic where the nuclear membrane ruptures, causing mislocalization of proteins and even organelles, and then either repairs or collapses. This phenomenon has been associated with increased genome instability, inflammation, and metastasis, suggesting that it could be a critical driver of cancer development. 
 

Lab News

July 2018

Ali Young is awarded a Ruth L. Kirschstein NRSA Postdoctoral Fellowship (F32) from the National Cancer Institute (NIH).

June 2018

Lucian DiPeso, a new graduate student in the Molecular and Cellular Biology Program, joins the lab.

 

May 2018

Emily Hatch is a 2018 Rita Allen Foundation Scholar.
Mari Cobb is off on a new scientific adventure in the Kalahari Desert. We will miss you, Mari!