Following completion of an M.D./Ph.D. degree in Molecular Cell Biology at Washington University in St. Louis, Brandon arrived in Seattle to pursue Pediatric Residency at Seattle Children’s Hospital in 2006. He entered the Pediatric Hematology/Oncology Fellowship program at the Fred Hutch/University of Washington in 2009, investigating hematopoietic stem cell biology under the mentorship of Irv Bernstein. Building on his graduate studies identifying the role of Notch signaling in developmental hematopoiesis, his research has focused on elucidating the signaling mechanisms regulating serial waves of embryonic hematopoiesis giving rise to unique lineages of blood and immune cells and the first hematopoietic stem cells.
Cyd moved here in 1981 from the Chicago area where she was a graduate of Northern Illinois University. That year she started at the Hutch in the Bernstein lab working with monoclonal antibody studies for leukemia and lymphoma which led to radiolabeled antibody research and to notch signaling pathways. She has also collaborated on several other projects to develop expertise in mouse models, designing experiments including the engraftment of human tumors and establishment of human engraftment using cord blood hematopoietic stem cells in transplantation. As a member of the Hadland lab, Cyd will provide expertise in murine models of transplantation toward understanding the mechanisms that control the early formation of blood stem cells such as gene activation and interactions with the microenvironment.
Joint affiliation with Bernstein lab