Lab Members

Philip Greenberg, MD

Philip Greenberg, MD

Title: Principal Investigator
Phone: 206.667.4462

Investigator Profile
Member & Head, Program of Immunology, Clinical Research Division, Fred Hutch  
Professor of Immunology and Medicine, University of Washington

Daniel Egan, MD

Daniel Egan, MD

Title: Assistant Member, Principal Investigator, Clinical Trials

Faculty Profile

Dan works closely with the Greenberg team to design and manage clinical trials that result from laboratory advances. 

Sylvia Lee, MD

Sylvia Lee, MD

Title: Joint Assistant Member, Principal Investigator, Clinical Trials

Faculty Profile

Sylvia works closely with the Greenberg team to design and manage clinical trials that result from laboratory advances.

Thomas Schmitt, PhD

Thomas Schmitt, PhD

Title: Research Associate

Tom is generating and optimizing expression vectors encoding high affinity WTI-specific TCR genes for use in T cell therapy trials. He is also developing novel methods for the directed evolution of tumor specific TCRs in vitro.

Ingunn Stromnes, PhD

Ingunn Stromnes, PhD

Title: Research Associate

Ingunn is investigating properties of target antigens and tumor microenvironments that influence the efficacy of adoptive T cell immunotherapy, using a spontaneous mouse model of pancreatic cancer. She is also testing means to abrogate negative regulators tumor-reactive T cells to improve the efficacy of adoptive immunotherapies for cancers and persistent viral infections.

Rachel Perret, PhD

Rachel Perret, PhD

Title: Postdoctoral Research Fellow

Rachel is expanding the cloned, high affinity, WT1-specific TCR repertoire to include several different HLA specificities as well as developing TCRs specific for the cancer testes antigen, cyclin A1. She is using bioinformatics screens, in vitro cell line testing and in vivo toxicity studies in HLA-transgenic mice to select optimal TCRs to translate into T cell therapy clinical trials for the treatment of pediatric and adult AML, as well as other cancers.

Luca Castelli, PhD

Luca Castelli, PhD

Title: Staff Scientist

Luca recently joined the lab after working as a Senior Scientist at Emergent BioSolutions. He has special expertise in bi-specific protein therapeutics, state-of-the-art flow cytometry and developing assays that can be used to measure immune responses and identify opportunities for optimization.

Kristin Anderson, PhD

Kristin Anderson, PhD

Title: Research Associate

Kristin studies properties of T cell migration and tumor microenvironments that impact the utility of adoptive T cell therapy for ovarian cancer. Chemotherapy, immune checkpoint blockade and abrogation of other negative T cell regulators and select cell depletion techniques are being tested as strategies that might enhance immunotherapy efficacy. 

Shannon Oda, PhD

Shannon Oda, PhD

Title: Postdoctoral Research Fellow

Shannon is developing engineered costimulatory constructs to improve T cell immunotherapy of leukemia. She is testing means to overcome specific obstacles to immunotherapy of solid tumors, using in vivo and in vitro models of lung cancer.

Leah Schmidt, PhD

Leah Schmidt, PhD

Title: Postdoctoral Research Fellow

Leah is a new fellow who will be using autochthonous mouse models of cancer to test strategies for improving the efficacy of adoptive immunotherapies.

Natalie Duerkopp

Natalie Duerkopp

Title: Project Manager
Breanna Bates

Breanna Bates

Title: Research Technician
Patrick Bonson

Patrick Bonson

Title: Research Technician
Jennifer Cao

Jennifer Cao

Title: Research Technician
Edison Chu

Edison Chu

Title: Research Technician
Andrew Daman

Andrew Daman

Title: Research Technician
Nicolas Garcia

Nicolas Garcia

Title: Research Technician
Jennifer Hotes

Jennifer Hotes

Title: Research Technician
Ayaka Hulbert

Ayaka Hulbert

Title: Research Technician
Lara Kropp

Lara Kropp

Title: Research Technician
Xiaoxia (Sasha) Tan

Xiaoxia (Sasha) Tan

Title: Research Technician
Kumiko Tsubota

Kumiko Tsubota

Title: Research Technician