POSITIONS AVAILABLE

 

Postdoctoral Research Fellow

A Postdoctoral Research Fellow position is available immediately in the Program in Immunology, Clinical Research Division at the Fred Hutchinson Cancer Research Center, Seattle, WA. The successful applicant will join the lab of Dr. Jarrod Dudakov to study the cellular and molecular mechanisms underlying immune regeneration.

Using common cellular and molecular biology techniques, the postdoctoral fellow will reveal novel pathways of regeneration in the thymus, the primary site of T cell development. Using this understanding, the successful applicant will then develop therapeutic strategies to enhance immune function that can be used in patients who have a depleted immune system due to aging, infection or common cancer therapies.

Desired skills and experience:

  • A PhD degree in Immunology, Cell Biology, Molecular Biology, Genetics or other closely related field
  • Molecular biology experience, including experience in DNA/RNA isolation, molecular cloning, cell transduction, and qPCR
  • Experience with immunological techniques such as ELISA, flow cytometry, and western blot
  • Training in animal procedures, including colony management and genotyping a plus

The successful candidate will be a highly motivated individual with a track record of productive research, exemplified by first author publication(s) and presentations, and willing to work in a highly collaborative environment.

Please apply with a letter summarizing previous work experience, personal strengths and future interests, CV, and contact information for three professional references. Send to jdudakov@fredhutch.org.

 

Experienced Laboratory Technician

The Program of Immunology within the Clinical Research Division is seeking an experienced technician to work on pre-clinical studies to understand the natural repair mechanisms in the thymus in order to develop novel strategies to boost immune function. The successful candidate will be closely involved with setting up a new laboratory and in setting up

The successful candidate will:

  • Assist in the maintenance of an animal colony, which involves frequent monitoring, setting up breeding, biopsies, DNA extraction and genotyping by PCR.
  • Assist in the design, implementation and interpretation of in vitro and in vivo studies to understand the processes of immune regeneration after damage.
  • Perform tissue culture using both cell lines and freshly isolated cells
  • Assess the cellular composition of the thymus using multi-color flow cytometry and FACS sorting.
  • Analyze protein and gene expression using qPCR, and ELISA.

A bachelor’s degree in a biological field and two years or more of post-bachelor’s laboratory research experience are required in the skill sets described above.

Must have experience with molecular biology techniques such as molecular cloning, DNA/RNA/protein isolation and analysis, rtPCR and qPCR. Additional expertise in immunology techniques such as flow cytometry is preferred but not required.

Required computer skills; Microsoft Excel, Prism (Graphpad), and FlowJo.

Excellent organizational and interpersonal skills, the ability to multi-task, and attention to detail are critical. 

Apply here.