September 2018

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Chen Group Newsletter | September 2018

Welcome to the September 2018 edition of the Chen Group Newsletter. This newsletter is where you can find the most relevant team and Center-wide updates, news, and highlights. 

Upcoming Events | Recent & Upcoming Presentations | Publications | Team Updates | Center Updates

Author: Eline Appelmans

Upcoming Events

September 11, 2018 Sayan Dasgupta Presents on Data Enrichment and VIRSCAN in hematologic cell transplant patients 

September 25, 2018 Jie Qin Presents on Regret and Preventive Health Behavior:  Conceptual Framework, Measurement, Findings, and Applications. 


We are currently scheduling presenters for Q1 of 2019 and are interested in hearing about both the big picture ideas in infectious disease biostatistics, bioinformatics, and epidemiology methods, as well as hands-on/technical details about your feild of expertise. If you are interested in presenting at one of our seminars please contact the group’s project manager, Elly Appelmans.

Public Speaking

Recent & Upcoming Conference Presentations 

Ying Qing Chen and Elly Appelmans: Presentation on Predicting PrEP Uptake and Adherence among Adolescent Girls and Young Women in Sub-Saharan Africa: Leveraging Programmatic and Clinical Trials Data to at Grantee Meeting, Madrid, Spain, October 22nd

Ying Qing Chen and Elly Appelmans: Attending HIVR4P, Madrid, Spain, October 21st - 25th 2018

Ying Qing Chen FDA Industry Workshop, Washington DC, September 12th - 18th 2018


Montaño MA, Dombrowski JC, Dasgupta S, Golden MR, Duerr A, Manhart LE, Barbee LA, Khosropour CM.Changes in Sexual Behavior and STI Diagnoses Among MSM Initiating PrEP in a Clinic Setting.AIDS Behav. 2018 Aug 16. PMID: 30117076. doi: 10.1007/s10461-018-2252-9. [Epub ahead of print]

Dasgupta S, Goldberg Y, & Kosorok M. (2013). Feature Elimination in Kernel Machines in moderately high dimensions. Annals of Statistics. 2018.

Team Updates

Grant Submitted:Lung Cytomegalovirus (CMV) reactivation in Adults with Suspected Ventilator-Associated Pneumonia (VAP)

Subaward PI: Ying Chen. PI: Ajit Limaye. Expect more news October 2018.

Grant Submitted: Impact of CMV and HHV-6 reactivation on morbidity (infection, delirium) ICU length of stay (LOS) in critically ill patients.

 PI: Michael Boeckh. Expect more news October 2018. 

The 4th Annual Summer Institute in Statistics for Big Data (SISBID)

Chen Group Summer Retreat

August 30th at Botanical gardens Wisteria Hall Arboretum. Honored guest speakers included: Ross Prentice from the Department of Biostatistics at the University of Washington and Ann Duerr from HOPE at Fred Hutchinson Cancer Research Center.

Jim Hughes: Design-based analyses of stepped wedge trials

Ann Duerr: TasP and cure strategies

Ross Prentice: Regression analysis of multivariate failure time data using single and double failure hazard rate models.


10th Summer Institute in Statistics and Modeling in Infectious Diseases (SISMID) takes place July 9-25, 2018, at the University

Small Research Grant Award Program Opened

This Award program supported by Dr. Chen is open to current Chen Group members aims to provide start-up funds for early career investigators to begin new lines of inquiry. The program will also provide the team with the experience and training in project leadership.

Proposals are encouraged from the team across a variety of topics to fund research with the product of 1 poster presentation and preliminary data for a future R01 grant. See SharePoint site for details.


Center Updates

BBE Picnic

September 18, 2018

12:00 p.m.

Carrie Bennette, Flatiron Health

Building external control arms for clinical trials using real-world data:

opportunities and challenges

Abstract. External control arms built from real-world databases could potentially support regulatory and coverage decisions, enabling more efficient clinical evidence generation; however, many questions remain regarding the reliability and comparability of outcomes derived from real-world data versus clinical trials. Carrie Bennette will discuss the challenges, opportunities and learnings from attempting to replicate the outcomes observed in the control arms of recent trials in oncology using longitudinal data from a curated electronic medical records database. Carrie will also discuss her experience as a data scientist who transitioned from academia to Flatiron Health, a healthcare technology company working to accelerate cancer research and improve outcomes for cancer patients.