Publications

2017 | 2016 | 2015 | 2013 | 2012 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2003 | 2000

2017

Zheng GX, Terry JM, Belgrader P, Ryvkin P, Bent ZW, Wilson R, Ziraldo SB, Wheeler TD, McDermott GP, Zhu J, Gregory MT, Shuga J, Montesclaros L, Underwood JG, Masquelier DA, Nishimura SY, Schnall-Levin M, Wyatt PW, Hindson CM, Bharadwaj R, Wong A, Ness KD, Beppu LW, Deeg HJ, McFarland C, Loeb KR, Valente WJ, Ericson NG, Stevens EA, Radich JP, Mikkelsen TS, Hindson BJ, Bielas JH. Massively parallel digital transcriptional profiling of single cells. Nat Commun. 2017 Jan 16;8:14049. doi: 10.1038/ncomms14049.

2016

Valente WJ, Ericson NG, Long AS, White PA, Marchetti F, Bielas JH. Mitochondrial DNA exhibits resistance to induced point and deletion mutations. Nucleic Acids Res. 2016 Aug 22. pii: gkw716. [Epub ahead of print]

2015

Sperber H, Mathieu J, Wang Y, Ferreccio A, Hesson J, Xu Z, Fischer KA, Devi A, Detraux D, Gu H, Battle SL, Showalter M, Valensisi C, Bielas JH, Ericson NG, Margaretha L, Robitaille AM, Margineantu D, Fiehn O, Hockenbery D, Blau CA, Raftery D, Margolin AA, Hawkins RD, Moon RT, Ware CB, Ruohola-Baker H. The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition. Nature Cell Biology. 2015 Dec;17(12):1523-35. doi: 10.1038/ncb3264. Epub 2015 Nov 16.

Gregory MT, Bertout JA, Ericson NG, Taylor SD, Mukherjee R, Robins HR, Drescher CW, Bielas JH. Targeted single molecule mutation detection with massively parallel sequencing. Nucleic Acids Research. 2015 Sep 17. doi: 10.1093/nar/gkv915.

2013

Robins HS, Ericson NG, Guenthoer J, O'Briant KC, Tewari M, Drescher CW, Bielas JH. Digital Genomic Quantification of Tumor-Infiltrating Lymphocytes. Science Translational Medicine. 2013 Dec 4. doi: 10.1126/scitranslmed.3007247. Associated Commentary.

Emerson RO, Sherwood AM, Rieder MJ, Guenthoer J, Williamson DW, Carlson CS, Drescher CW, Tewari M, Bielas JH, Robins HS. High-throughput sequencing of T cell receptors reveals a homogeneous repertoire of tumor-infiltrating lymphocytes in ovarian cancer. Journal of Pathology. 2013 Sept
11. doi: 10.1002/path.4260.

Taylor SD, Ericson NG, Burton JN, Prolla TA, Silber JR, Shendure J, Bielas JH. Targeted enrichment and high-resolution digital profiling of mitochondrial DNA deletions in human brain. Aging Cell. 2013 Aug 2. doi: 10.1111/acel.12146.

Laurie MT, Bertout JA, Taylor SD, Burton JN, Shendure JA, Bielas JH. Simultaneous digital quantification and fluorescence-based size characterization of massively parallel sequencing libraries. Biotechniques. 2013 Aug;55(2):61-7. doi: 10.2144/000114063.

Hu J, Locasale JW, Bielas JH, O'Sullivan J, Sheahan K, Cantley LC, Vander Heiden MG, Vitkup D. Heterogeneity of tumor-induced changes in the human metabolic network. Nat Biotechnol. 2013 Jun;31(6):522-9. doi: 10.1038/nbt.2530. Epub 2013 Apr 21.

2012

Ericson NG, Kulawiec M, Vermulst M, Sheahan K, O'Sullivan J, Salk JJ, Bielas JH. (2012) Decreased Mitochondrial DNA Mutagenesis in Human Colorectal Cancer. PLoS Genet 8(6): e1002689. doi:10.1371/journal.pgen.1002689. Associated Commentary.

2010

Kulawiec M, Salk JJ, Ericson NG, Wanagat J, Bielas JH. Generation, function, and prognostic utility of somatic mitochondrial DNA mutations in cancer. Environ Mol Mutagen. 2010 Jun;51(5):427-39

2009

Bielas JH, Schmitt MW, Icreverzi A, Ericson NG, Loeb LA. Molecularly evolved thymidylate synthase inhibits 5-fluorodeoxyuridine toxicity in human hematopoietic cells. Hum Gene Ther. 2009 Dec;20(12):1703-7.

2008

Vermulst M, Wanagat J, Kujoth GC, Bielas JH, Rabinovitch PS, Prolla TA, Loeb LA. DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice. Nat Genet. 2008 Apr;40(4):392-4.

2007

Vermulst M, Bielas JH, Kujoth GC, Ladiges WC, Rabinovitch PS, Prolla TA, Loeb LA. Mitochondrial point mutations do not limit the natural lifespan of mice. Nat Genet. 2007 Apr;39(4):540-3. Associated Commentary.

Loeb LA, Bielas JH. Limits to the Human Cancer Genome Project? Science. 2007 Feb 9;315(5813):762; author reply 764-5.

2006

Bielas JH, Loeb KR, Rubin BP, True LD, Loeb LA. Human cancers express a mutator phenotype. Proc Natl Acad Sci U S A. 2006 Nov 28;103(48):18238-42. Associated Commentary.

Bielas JH. Non-transcribed strand repair revealed in quiescent cells. Mutagenesis. 2006 Jan;21(1):49-53.

2005

Bielas JH, Loeb LA. Quantification of random genomic mutations. Nat Methods. 2005 Apr;2(4):285-90. Associated Commentary.

2003

Bielas JH, Heddle JA. Elevated mutagenesis and decreased DNA repair at a transgene are associated with proliferation but not apoptosis in p53-deficient cells. Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12853-8.

2000

Bielas JH, Heddle JA. Proliferation is necessary for both repair and mutation in transgenic mouse cells. Proc Natl Acad Sci U S A. 2000 Oct 10;97(21):11391-6. Associated Commentary.

A complete publication list can be found here.