Michael Wu Group -- Publications

Wu Group Publications

*Underlined denoted group member.

  Link to Google Scholar Profile

    Submitted

  1. Clark, J.J., Maity, A., Harmon, Q.E., Engel, S.M., Epstein, M.P., Wu, M.C. "Gene and region based testing of gene-gene interactions for quantitative traits with the SNP-Set Kernel Interaction Test (SKIT)". Submitted.
  2. Stewart, T.G., Wu, M.C., Zeng, D. "The augmented and weighted support vector machine and for classification with missing covariates". Submitted.
    [*** An earlier version won the 2014 ENAR Poster Competition Award AND the 2015 ENAR Distinguished Student Paper Award***]
  3. Dutcher, J.P., Manola, J., Gordon, M.S., Richardson, R.L., Sosman, J.A., Cella, D., Fairclough, D., Kasimis, B.S., Sledge, G.W., Jr., Wu, M.C., McNeel, D.G., Keefe, S.M., Carducci, M.A., Roach, R.W., Hudes, G.R., Wilding, G.  ``Phase III randomized trial of interferon alfa-2b (IFN) along versus interferon alfa-2b plus thalidomide in patients with previously untreated metastatic or unresectable renal cell carcinoma (E2898): a trial of the Eastern Cooperative Oncology Group.'' Submitted.
  4. Teran Hidalgo, S.J., Wu, M.C., Engel, S.M., Kosorok, M.R. "Goodness-of-fit test for smoothing spline ANOVA models: missing covariates and interaction terms".
  5. Zhao, N., Zhan, X., Huang, Y-T., Almli, L.M., Smith, A., Epstein, M.P., Conneely, K.N., Wu, M.C. "Kernel machine methods for integrative analysis of genome-wide methylation and genotyping studies"
  6. Teran Hidalgo, S.J., Wu, M.C., Chen, M., Kosorok, M.R. "Hierarchical clustering via distance covariance".

  7. 2017 and In Press

  8. Plantinga, A., Zhan, X., Zhao, N., Chen, J., Jenq, R.R., Wu, M.C. (2017). "MiRKAT-S: A community-level test of association between the microbiota and survival times". Microbiome, 5(1): 17. PMC5299808 Open Access
  9. Zhan, X., Tong, X., Zhao, N., Maity, A., Wu, M.C.#, Chen, J.# (2017). "A small-sample multivariate kernel machine test for microbiome association studies". Genetic Epidemiology, 41(3):210-220. PDF
    [#Joint Corresponding Author]
  10. Zhan, X., Plantinga, A., Zhao, N., Wu, M.C. (2017). "A fast small-sample kernel independence test with application to microbiome association studies". Biometrics, In Press. PDF
    [*** An earlier version won an ASA Biometrics Section JSM Paper Award ***]
  11. Zhan, X., Zhao, N., Plantinga, A., Thornton, T.A.,  Conneely, K.N., Epstein, M.P., Wu, M.C. (2017). ``Dual kernel-based association test for genome-wide association studies with high-dimensional structured traits''. Genetics, 206(4): 1779-1790. PDF
  12. Zhan, X., Wu, M.C. (2017). "Note on testing and estimation in marker-set association study using semiparametric quantile regression kernel machine". Biometrics, In Press.
  13. Reese, S.E., Zhao, S., Wu, M.C., Joubert, B.R., Parr, C.L., Håberg, S.E., Ueland, P.M., Nilsen, R.M., Midttun, O., Vellset, S.E., Peddada, S., Nystad, W., London, S.J. (2017). "DNA methylation score as a biomarker in newborns for sustained maternal smoking during pregnancy". Environmental Health Perspectives, 125(4):760-766. PMC5381987
  14. Mitchell, C.M., Srinivasan, S., Zhan, X., Wu, M.C., Reed, S.D., Guthrie, K.A., LaCroix, A.Z., Fiedler, T., Munch, M., Liu, C., Hoffman, N., Blair, I.A., Newton, K., Freeman, E.W., Joffe, H., Cohen, L., Fredricks, D.N. (2017). ``Vaginal microbiota and genitourinary menopausal symptoms: a cross sectional analysis''. Menopause, In Press.
  15. Golob, J.L., Pergam, S.A., Srinivasan, S., Fiedler, T.L., Liu, C., Garcia, K., Mielcarak, M., Ko, D., Aker, S., Marquis, S., Loeffelholz, T., Plantinga, A., Wu, M.C., Celustka, K., Morrison, A., Woodfield, M., Fredricks, D.N. (2017). ``The stool microbiotal at neutrophil recovery is predictive for severe acute graft versus host disease after hematopoietic cell transplantation.'' Clinical Infectious Diseases, In Press.
  16. Bauer, A.E., Avery, C.L., Shi, M., Weinberg, C.R., Olshan, A.F., Harmon, Q.E., Luo, J., Yang, J., Manuck, T., Wu, M.C., Williams, N., McGinnis, R., Morgan, L., K'ungsoyr, K., Trogstad, L., Magnus, P., Engel, S.M. (2017). ``A family-based study of carbon monoxide and nitric oxide signaling genes and preeclampsia''. Paediatric and Perinatal Epidemiology, In Press.

  17. 2016

  18. He, Q.#, Cai, T., Liu, Y., Zhao, N., Harmon, Q.E., Almli, L.M., Binder, E.B., Engel, S.M., Ressler, K.J., Conneely, K.N., Lin, X., Wu, M.C.# (2016). "Prioritizing individual variants after kernel machine testing using variable selection". Genetic Epidemiology, 40(8):722-731. PMC5118060 PDF
    [#Joint Corresponding Author]
  19. Chen, J., Chen, W., Zhao, N., Wu, M.C., Schaid, D.J. (2016). "Small-sample kernel association tests for human genetic and microbiome association studies". Genetic Epidemiology, 40:5-19. PMC4679685
  20. Lin, Xinyi, Lee, S., Wu, M.C., Wang, C., Chen, H., Li, Z., Lin, X. (2016). "Test for rare variants by environment interactions in sequencing association studies". Biometrics, 72: 156-164. PMC4733434
  21. Zhan, X., Girirajan, S., Zhao, N., Wu, M.C., Ghosh, D. (2016). "A novel copy number variants kernel association test with application to autism spectrum disorders studies". Bioinformatics, 32 (23): 3603-3610. PMC5181531
  22. Dai, H., Wu, G., Wu, M., Zhi, D. (2016). "An optimal bahadur-efficient method in detection of sparse signals with applications to pathway analysis in sequencing association studies". PLOS One, 11(7):e0152667. PMC4933358
  23. Joubert, B.R., den Dekker, H.T., Felix, J.F., Bohlin, J., Beckett, E., Tiemeier, H., van Meurs, J.B., Uitterlinden, A.G., Hofman, A., Håberg, S.E., Reese, S.E., Andreassen, B.K., Nilsen, R.M., Vollset, S.E., Midttun, O., Ueland, P.M., Wu, M.C., Wang, T., Peddada, S.D., Jaddoe, V.W.V., Nystad, W., Dujits, L., London, S.J. (2016). "Maternal plasma folate during pregnancy impacts di fferential DNA methylation in an epigenome-wide meta-analysis of newborns". Nature Communications, 7:10577. PMC474995
  24. Suderman, M., Stene, L.C., Bohlin, J., Page, C.M., Holvik, K., Parr, C.L., Magnus, M.C., Håberg, S.E., Joubert, B.R., Wu, M.C., London, S.J., Relton, C., Nystad, W. (2016). "25-hydroxyvitamin D in pregnancy and genome wide cord blood DNA methylation in two pregnancy cohorts (MoBa and ALSPAC)". The Journal of Steroid Biochemistry and Molecular Biology, 159:102-109. PMC4829940
  25. Joubert, B.R., Felix, J.F., Yousefi , P., Bakulski, K.M., Just, A.C., Breton, C., Reese, S., Markunas, C., ..., Wu, M.C., ... , London, S.J. (2016). "DNA methylation in newborns and maternal smoking in pregnancy: Genome-wide consortium meta-analysis". The American Journal of Human Genetics, 98(4):680-96. PMC4833289
  26. [*** This article selected by AJHG as one of the "Best of" 2015-2016 ***]
  27. Rotroff , D.M., Joubert, B.R., Marvel, S.W., Håberg, S.E., Wu, M.C., Nilsen, R.M., Ueland, P.M., Nystad, W., London, S.J., Motsinger-Reif, A. (2016). "Maternal smoking impacts key biological pathways in newborns through epigenetic modi cation in utero". BMC Genomics, 17(1):976. PMC5124223

  28. 2015

  29. Zhao, N., Chen, J., Carroll, I.M., Ringel-Kulka, T., Epstein, M.P., Zhou, H., Zhou, J.J., Ringel, Y., Li, H., Wu, M.C.  (2015). "Testing in microbiome profiling studies with MiRKAT, the Microbiome Regression-based Kernel Association Test". The American Journal of Human Genetics, 96(5): 797 - 807.  PMC4570290 PDF
  30. Zhao, N., Bell, D.A., Maity, A., Staicu, A.-M., Joubert, B.R., London, S.J., Wu, M.C. (2015). "Global analysis of methylation profiles from high resolution CpG data". Genetic Epidemiology, 39:53-64. PMC4314375 PDF
  31. Urrutia, E., Lee, S., Maity, A., Zhao, N., Shen, J., Li, Y., Wu, M.C. (2015). "Rare variant testing across methods and thresholds using the multi-kernel sequence kernel association test (MK-SKAT)". Statistics and Its Interface, 8:495-505. PMC4698916 PDF
    [*** An earlier version won an ASHG Predoctoral Trainee Research Semifinalist Award***]
  32. Family, L., Bensen, J.T., Troester, M.A., Wu, M.C., Anders, C.K., Olshan, A.F. (2015). "Single nucleotide polymorphisms in DNA bypass polymerase genes and association with  breast cancer and breast cancer subtypes among African Americans and Whites". Breast Cancer Research and Treatment, 149(1):181-90. PMC4498665
  33. Hair, B.Y., Troester, M.A., Edmiston, S.N., Parrish, E.A., Robinson, W.R.,  Wu, M.C., Olshan, A.F., Swift-Scanlan, T., Conway, K. (2015). "Body mass index is associated with gene methylation in estrogen receptor-positive breast tumors". Cancer Epidemiology, Biomarkers & Prevention, 24(3):580-86. PMC4355173
  34. Hair, B.Y., Xu, Z., Kirk, E., Harlid, S., Sandhu, R., Robinson, W.R., Wu, M.C., Olshan, A.F., Conway, K., Taylor, J., Troester, M.A. (2015). "Body mass index associated with genome-wide methylation in breast tissue". Breast Cancer Research and Treatment, 151(2):453-63. PMC4474159
  35. Bohlin, J., Andreassen, B.K., Joubert, B.R., Magnus, M., Wu, M.C., Parr, C.L., Håberg, S.E., Magnus, P., Reese, S.E., Stoltenberg, C., London, S.J., Nystad, W. (2015). "Effect of maternal gestational weight gain on offspring DNA methylation: a follow-up to the ALSPAC cohort study". BMC Research Notes, 8:321. PMC4518864
  36. Geybels, M.S., Zhao, S., Wong, C., Bibikova, M., Klotzle, B., Wu, M., Ostrander, E.A., Fan, J., Feng, Z., Stanford, J.L. (2015). "Epigenome-wide pro filing of DNA methylation in paired prostate cancer versus adjacent benign tissue". The Prostate, 75(16):1941-50. PMID:26383847

  37. 2014

  38. Wu, M.C., Joubert, B.R., Kuan, P.F., Håberg, S.E., Nystad, W., Peddada, S.D., London, S.J. (2014). "A systematic assessment of normalization approaches for the Infinium 450k methylation platform". Epigenetics, 9(2): 212-222. PMC3962542 Open Access
  39. Engel, S.M.#, Joubert, B.R.#, Wu, M.C.#, Olshan, A.F., Håberg, S.E., Ueland, P.M., Nystad, W., Nilsen, R.M., Vollset, S.E., Peddada, S.D., London, S.J. (2014). "Neonatal genome-wide methylation patterns in relation to birthweight in the Norwegian Mother and Child Birth Cohort". American Journal of Epidemiology, 179(7): 834-42. PMC3969535
    [#Equal Contribution]
    [*** This paper was selected as an AJE "Editor's Choice" Article  AND a 2014 AJE and SER "Paper of the Year"***]
  40. Sanders, A.P., Smeester, L., Rojas, D., DeBussycher, T., Wu, M.C., Wright, F.A., Zhou, Y., Laine, J.E., Rager, J.L., Swamy, G.K., Ashley-Koch, A., Miranda, M.L., Fry, R.C. (2014). "Cadmium exposure and the epigenome: exposure-associated patterns of DNA methylation in leukocytes from mother-baby pair". Epigenetics, 9(2): 318-329. PMC3962531
  41. Ebert, C.S., McKinney, K.A., Urrutia, G., Wu, M., Rose, A.S., Fleischman, G.M., Thorp, B., Senior, B.A., Zanation, A.M. (2014). "Expression of protease-activated receptors in allergic fungal rhinosinusitis". International Forum of Allergy & Rhinology, 4(4): 266-71. PMID:24500840
  42. Harmon, Q.E., Engel, S.M., Wu, M.C., Moran, T., Luo, J., Stuebe, A., Avery, C., Olshan, A. (2014). "Polymorphisms in inflammatory genes associated with term SGA and preeclampsia". American Journal of Reproductive Immunology, 71(5): 472-84. PMC4040534
  43. Joubert, B.R., Håberg, S.E., Bell, D.A., Nilsen, R.M., Vollset, S.E., Midttun, O., Ueland, P.M., Wu, M.C., Nystad, W., Peddada, S.D., London, S.J. (2014). "Maternal smoking and DNA methylation in newborns: In utero effect or epigenetic inheritance?". Cancer Epidemiology, Biomarkers & Prevention, 23(6): 1007-17. PMC4140220
  44. Nylander-French, L.A., Wu, M.C., Boyner, J., Smeester, L., Sanders, A.P., French, J.E., Fry, R.C. (2014). "DNA methylation modifies urine biomarker levels in 1,6-hexamethylene diisocyanate (HDI) exposed workers: a pilot study". Toxicology Letters, 231(2): 217-26. PMID:25445006

  45. 2013

  46. Wu, M.C., Maity, A., Lee, S., Simmons, E.M., Harmon, Q.E., Lin, Xinyi, Engel, S.M., Molldrem, J.J., Armistead, P.M. (2013). "Kernel machine SNP-set testing under multiple candidate kernels". Genetic Epidemiology, 37(3): 267-75. PMC3769109 PDF
  47. Byrnes, A.E., Wu, M.C., Wright, F.A., Li, M., Li, Y. (2013). "The value of statistical or bioinformatics annotation for rare variant association with quantitative trait". Genetic Epidemiology, 37(7): 666-74. PMC4083762
  48. Carroll, I.M., Ringel-Kulka, T., Ferrier, L., Wu, M.C., Siddle, J.P., Bueno, L., Ringel, Y. (2013). "Fecal protease activity is associated with compositional alterations in the intestinal microbiota". PLOS One, 8(10): e78017. PMC3798377
  49. Harmon, Q.E., Engel, S.M., Olshan, A., Moran, T., Stuebe, A., Luo, J., Wu, M.C., Avery, C. (2013). "Association of polymorphisms in natural killer cell-related genes with preterm birth". American Journal of Epidemiology, 178(8): 1208-18. PMC3792727
  50. Cleary, S.P., Jeck, W.R., Zhao, X., Chen, K., Selitsky, S.R., Savich, G.L., Tan, T.X, Wu, M.C., Getz, G., Lawrence, M.S., Parker, J.S., Li, J, Powers, S., Kim, H., Fischer, S., Giundi, M., Ghanekar, A., Chiang, D.Y. (2013). "Identification of Driver Genes in Hepatocellular Carcinoma by Exome Sequencing". Hepatology, 58(5): 1693-1702. PMC3830584
  51. Bencharit, S., Baxter, S.S., Carlson, J., Byrd, W.C., Mayo, M.V., Border, M.B., Kohltfarber, H., Urrutia, E., Saldarriaga, I., Howard-Williams, E.L., Offenbacher, S., Wu, M.C., Buse, J.B. (2013). "Salivary proteins associated with hyperglycemia in diabetes: a proteomic analysis". Molecular Biosystems, 9: 2785-97. PMC3888809
  52. Bailey, K.M., Wu, M.C., Ward, W.O., Smeester, L., Rager, J.E., Garcia-Varga, G., Del Razo, L., Drobna, Z., Styblo, M., Fry, R.C. (2013). "Arsenic and the epigenome: interindividual differences in arsenic metabolism related to distinc patterns of DNA methylation". Journal of Biochemical and Molecular Toxicology, 27(2):106-115. PMC3892431
  53. Schuck, R.N., Theken, K.N., Edin, M.L., Caughey, M., Bass, A., Ellis, K., Tran, B., Steele, S., Simmons, B.P., Lih, B.P., Tomer, K.B., Wu, M.C., Hinderliter, A.L., Stouffer, G.A., Zeldin, D.R., Lee, C.R. (2013). "Cytochrome P450 derived eicosanoids and vascular function in coronary artery disease patients". Atherosclerosis, 227:442-48. PMC3638946

  54. 2012

  55. Lee, S., Wu, M.C., Lin, X. "Optimal tests for rare variant effects in sequencing association studies". (2012). Biostatistics, 13(4): 762-75. PMC3440237 PDF
  56. Joubert, B.R., Håberg, S.E., Nilsen, R.M., Wang, X., Vollset, S.E., Murphey, S.K., Huang, Z., Hoyo, C., Midttun, O., Cupul-Uicab, L.A., Ueland, P.M., Wu, M.C., Nystad, W., Bell, D.A., Peddada, S.D., London, S.J. (2012). "450K Epigenome-wide scan identifies differential DNA methylation in newborns related to maternal smoking during pregnancy". Environmental Health Perspectives, 120: 1425-31. PMC3491949
  57. [*** This article selected by EHP as the 2013 Paper of the Year ***]
  58. Wu, H., Wu, M.C., Zhi, D., Santorico, S.A., Cui, X. (2012). "Statistical analysis for next generation sequencing -- meeting report". Frontiers in Genetics, 3:128. PMC3395795
  59. Glickman, S.W., Shofer, F.S., Wu, M.C., Scholer, M.J., Ndubuizu, A., Cairns, C.B., Glickman, L.T. (2012). "Development and validation of a prioritization rule for obtaining an immediate 12-lead electrocardiogram in the emergency department to identify ST-elevation myocardial infarction". The American Heart Journal, 163(3): 372-382. PMID22424007
  60. Theken, K.N., Schuck, R.N., Edin, M.L., Tran, B., Ellis, K., Bass, A., Lih, F.B., Tomer, K.B., Poloyac, S.M., Wu, M.C., Hinderliter, A.L., Zeldin, D.C, Stouffer, G.A., Lee, C.R. (2012). "Evaluation of cytochrome P450-derived eicosanoids in humans with stable atherosclerotic cardiovascular disease". Atherosclerosis, 222(2): 530-536. PMC3361525

  61. 2011

  62. Wu, M.C.#, Lee, S.#, Cai, T., Li, Y., Boehnke, M., Lin, X. (2011). "Rare variant association testing for sequencing data with the sequence kernel association test (SKAT)". The American Journal of Human Genetics, 89, 82-93. PMC3135811 PDF
    [#Equal Contribution]
  63. [*** This article selected by AJHG as one of the "Best of" 2011-2012 ***]
  64. Lin, X., Cai, T., Wu, M.C., Zhou, Q., Liu, G., Christiani, D.C., Lin, X. (2011). "Kernel machine SNP-set analysis for censored survival outcomes in genome-wide association studies". Genetic Epidemiology, 35, 620-31. PMC3373190
  65. Ter-Minassian, M., Wang, Z., Asomaning, K., Wu, M.C., Paulus, J.K., Liu, G., Bradbury, P.A., Zhai, R., Su, L., Frauenhoffer, C.S., Hooshman, S.M., De Vivo, I., Lin, X., Christiani, D.C., Kulke, M.H. (2011). "Genetic associations with sporadic neuroendocrine tumor risk". Carcinogenesis, 32(8):1216-22. PMC3149206

  66. 2010

  67. Wu, M.C., Kraft, P., Epstein, M.P., Taylor, D.M., Chanock, S.J., Hunter, D.J., and Lin, X. (2010). "Powerful SNP set analysis for case-control genome wide association studies". The American Journal of Human Genetics, 86, 929-942. PMC3032061 PDF
  68. Locke, A.E., Dooley, K.J., Tinker, S.W., Cheong, S.Y., Feingold, E., Allen, E.G., Freeman, S.B., Torfs, C.P., Cua, C., Epstein, M.P., Wu, M.C., Lin, X., Capone, G., Sherman, S.L., Bean, L.J.H. (2010). "Variation in folate pathway genes contributes to risk of congenital heart defects among individuals with Down syndrome". Genetic Epidemiology, 34(6):613-23. PMC3378053
  69. Liu, C.Y., Wu, M.C., Chen, F., Ter-Minassian, M., Asomaning, K., Zhai, R., Wang, Z., Su, L., Heist, R.S., Kulke, M.H., Lin, X., Liu, G., Christiani, D.C. (2010). "A large-scale genetic association study of esophageal adenocarcinoma risk". Carcinogenesis, 31(7):1259-63. PMC2893800

  70. 2009 and earlier

  71. Wu, M.C., Zhang, L., Wang, Z., Christiani, D.C., Lin, X. (2009). "Sparse linear discriminant analysis for simultaneous gene set/pathway significance test and gene selection". Bioinformatics, 25,1145-1151. PMC2732305 PDF
    [*** An earlier version received the 2008 ICSA Student Paper Award and corresponding technical report received the 2008 ASA Statistical Computing and Graphics Section Student Paper Award***]
  72. Huang, Y.T., Heist, R.S., Chirieac, L.R., Lin, X., Skaug, V., Haugen, A., Wu, M.C., Wang, Z., Su, L., Asomaning, K., Christiani, D.C. (2009). "Genome-wide analysis of survival in early-stage non-small cell lung cancer". Journal of Clinical Oncology, 27(16):2660-2667. PMC2690391
  73. Wu, M.C., Lin, X. (2009). "Prior biological knowledge based approaches for the analysis of genome-wide expression profiles using gene sets and pathways". Statistical Methods in Medical Research,18(6):577-93. PMC2827341 PDF
  74. Harezlak, J.#, Wu, M.C.#, Wang, M., Schwartzman, A., Christiani D.C., Lin, X. (2008). "Biomarker discovery for arsenic exposure using functional learning of mass-spectrometry proteomic data". Journal of Proteome Research, 7(1):217-24. PMID18173220 PDF
    [#Equal Contribution]
  75. Engbring, J.A., Hossain, R., VanOsdol, S.J., Kaplan-Singer, B., Wu, M., Hibino, S., Koblinski, J.E. (2008). "The laminin alpha-1 chain derived peptide, AG73, increases fibronectin levels in breast and melanoma cancer cells". Clinical and Experimental Metastasis, 25(3):241-252. PMID18185912
  76. Ji, H., Ramsey, M.R., Hayes, D.N., Fan, C., McNamara, K., Kozlowski, P., Torrice, C., Wu, M.C., Shimamura, T., Perera, S., Liang, M-C., Cai, D., Naumov, G.N., Bao, L., Contreras, C., Li, D., Chen, L., Krishnamurthy, J., Koivunen, J., Chirieac, L.R., Padera, R., Bronson, R.T., Lindeman, N.I., Christiani, D.C., Lin, X., Shapiro, G.I., Janne, P.A., Johnson, B., Meyerson, M., Kwiatkowski, D.J., Castrillon, D.H., Badeesy, N.,Sharpless, N.E., Wong, K-K. (2007). "LKB1 modulates lung cancer differentiation and metastasis". Nature, 448(7155):807-10. PMID17676035
  77. Koblinski, J.E., Wu, M., Demeler, B., Kleinman, H.K. (2005). "Matrix cell adhesion activation by non-adhesion proteins". Journal of Cell Science, 118(Pt 13):2965-74. PMID15976454
  78. Koblinski, J.E., Kaplan-Singer, B.R., VanOsdol, S.J., Wu, M., Engbring, J.A., Goldsmith, C.M., Piper, J.T., Vostal, J.G., Harms, J.F., Welch, D.R., Kleinman, H.K. (2005). "Endogenous osteonectin/SPARC/BM-40 expression inhibits MDA-MB-231 breast cancer cell metastasis". Cancer Research, 65(16):7370-7. PMID16103089

  79. Technical Reports

  80. Li, L., Wu, M.C., Lin, X. "Prioritizing phenotype-associated uncommon variants in sequencing association studies". Technical Report.
  81. Lee, S., Wu, M.C., Cai, T., Li, Y., Boehnke, M., Lin, X. (2011). "Power and sample size calculations for designing rare variant sequencing association studies". Technical Report, Harvard University. PDF
  82. Wu, M.C., Cai, T., Lin, X. "Testing for regression coefficients in LASSO regularized regression". Technical Report.
    [*** An earlier version received an ENAR Student Paper Award ***]
  83. Wu, M.C. (2009). "Statistical methods for high-dimensional genomic data". Ph.D. Dissertation, Harvard University.
  84. Wu, M.C., Zhang, L., Lin, X. (2008)."Two group classification using sparse linear discriminant analysis". Technical Report, Harvard University.
    [*** An earlier version won the 2008 ASA Statistical Computing and Graphics Section Student Paper Award ***]
  85. Wu, M.C., Lin, X. (2007). "Adaptively penalized logistic regression for testing the significance of gene pathways". Technical Report, Harvard University.