In January, the Tapscott Lab attended the 15th Annual Friends of FSH Research Gala.
In January, Suja Jagannathan's paper on post-transcriptional gene regulation in DUX4-expressing cells was published in eLife: Quantitative proteomics reveals key roles for post-transcriptional gene regulation in the molecular pathology of facioscapulohumeral muscular dystrophy.
In November, Danielle Hamm joined the lab as a Postdoctoral Research Fellow. Welcome, Danielle!
Congratulations to Rebecca Resnick on defending her PhD on October 22nd! Rebecca will stay in the lab for a few more months before moving on to complete her MD training as part of UW's Medical Scientist Training Program.
In October, our multi-center collaboration through the Seattle Paul D. Wellstone Muscular Dystrophy Cooperative Research Center published a paper in Human Molecular Genetics: MRI-informed muscle biopsies correlate MRI with pathology and DUX4 target gene expression in FSHD.
In September, Stephen was appointed to lead a new, multidisciplinary Developmental Oncology Program at Fred Hutch. Congratulations, Stephen!
In June, Nick Sutliff joined the lab as a Research Technician. Welcome, Nick!
In June, Amy Campbell received FSH Society's 2018 Young Investgator Award. Congratulations, Amy!
In June, Amy Spens and Andrew Smith, graduate students in the University of Washington's Molecular and Cellular Biology Program, joined the lab. Welcome, Andrew and Amy!
In April, Jessica Kumar joined the lab as a Research Technician. Welcome, Jessica!
In March, our Postdoc, Jongwon Lim, joined Universal Cells as Scientist II. Congratulations, Jongwon!
In December, our Postdoc, Suja Jagannathan, left the lab to start her own lab in the Department of Biochemistry and Molecular Genetics at the University of Colorado School of Medicine. Congratulations, Professor Jagannathan!
In January, the Tapscott Lab attended the 14th Annual Friends of FSH Research Gala.
Photos from the 14th Annual Friends of FSH Research Gala.
In November, our Postdoc, Ashlee Langford, joined the Fred Hutch Institutional Review Department as IACUC Assistant/Post Approval Monitor. Congratulations, Ashlee!
In June, our Senior Research Technician, Jun Wen Zhong, left the lab to join Xealth as a Product Manager. Congrats, Jun!
In June, Sean Bennett joined the lab as a Research Technician. Welcome, Sean!
Congratulations to Jenn Whiddon on defending her PhD on December 2nd! After a few more months in the lab, Jenn will be moving back to her native Texas to pursue her post-PhD endeavors.
In February, our Postdoc, Melissa Conerly, joined OncoResponse as a Scientist in Immune-Oncology. Congrats, Melissa!
This winter, our Staff Scientist, Laurie Snider, retired, but will stay onboard part-time for special projects. So glad we'll still see you around, Laurie!
In Sept., Amy Campbell, PhD was awarded a fellowship on the Chromosome Metabolism and Cancer Training Grant at Fred Hutch to study DUX4 as a regulator of pluripotency in cancer.
Yosuke Hiramuki, PhD was awarded a three-year fellowship in 2015 from FSH Society to determine the effectiveness of increased SMCHD1 expression to suppress DUX4 in FSHD muscle cells and model mice.
Sujatha Jagannathan, PhD has been awarded a three-year fellowship by FSH Society to study the novel role for reduced RNA quality control in FSHD pathogenesis. Suja is co-mentored by Stephen Tapscott, MD, PhD and Robert Bradley, PhD at Fred Hutch.
Jenn Whiddon received a prestigious three year graduate research fellowship from the National Science Foundation in 2013.
Sean Shadle was selected to receive the Cell and Molecular Biology Training Grant at the University of Washington in 2015.
Jong-Won Lim, PhD was awarded a three-year fellowship by Friends of FSH Research in 2013 to study epigenetic silencing of the 4qD4Z4 repeat array in FSHD.
Rebecca Resnick was selected to receive the Genome Training Grant at the University of Washington in 2016.
Fred Hutch neurologist and researcher to provide advice on policy issues
Dr. Tapscott has been appointed to the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) advisory council.
Fred Hutchinson Cancer Research Center partners with GlaxoSmithKline to develop muscular dystrophy therapeutics
The goal of the new agreement is to develop a small-molecule-based medicine to potentially reverse facioscapulohumeral muscular dystrophy, or FSHD, by inhibiting the activity of a protein that is incorrectly expressed by the DUX4 gene in people with the disease. learn more
An international team of researchers has made a critical advance in determining the cause of a common form of muscular dystrophy.
The findings, published in the Aug. 20 issue of Science, shed new light on how a genetic mutation identified nearly 20 years ago causes the disease. The mutation is associated with the majority of FSHD cases, which affects some 300,000 people worldwide. learn more
Four Fred Hutchinson Cancer Research Center teams win Hartwell Innovation Fund awards
Each team of scientists will receive $80,000 grants to jump-start innovative and high-risk, high-reward research opportunities.
Dr. Stanley Riddell, Clinical Research, and Dr. Stephen Tapscott, Human Biology, will ask whether DUX4 expression in antigen presenting cells can induce T-cells to recognize CT antigens and mount an immune response against cells bearing those antigens. This approach could lead to a universal cancer vaccine capable of targeting multiple different types of cancer. more