OLSON LAB -- Publications



Toledo CM, Ding Y, Hoellerbauer P, Davis RJ, Basom R, Girard EJ, Lee E, Corrin P, Hart T, Bolouri H, Davison J, Zhang Q, Hardcastle J, Aronow BJ, Plaisier CL, Baliga NS, Moffat J, Lin Q, Li XN, Nam DH, Lee J, Pollard SM, Zhu J, Delrow JJ, Clurman BE, Olson JM, Paddison PJ. Genome-wide CRISPR-Cas9 Screens Reveal Loss of Redundancy between PKMYT1 and WEE1 in Glioblastoma Stem-like Cells. Cell Rep. 2015 Dec 22;13(11):2425-39

Moreno-Gonzalez A, Olson JM, Klinghoffer RA. Predicting responses to chemotherapy in the context that matters-the patient. Molecular and Cellular Oncology. 2015 June 10.

Hoffman L, Fouladi M, Olson JM, Daryani VM, Stewart CF, Wetmore C, Kocak M, Onar-Thomas A, Wagner L, Gururangan S, Packer R, Blaney S, Gajjar A, Kun LE, Boyett JM, Gilbertson JR. Phase I Trial of Weekly MK-0752 in Children with Refractory Central Nervous System Malignancies: A Pediatric Brain Tumor Consortium Study. Childs Nerv Syst. 2015 May 1

Parrish-Novak, J, Holland EC, Olson JM.  2015.  Image-Guided Tumor Resection.. Cancer journal (Sudbury, Mass.). 21(3):206-12. Abstract

Klinghoffer, RA, Bahrami BS, Hatton BA, Frazier JP, Moreno-Gonzalez A, Strand AD, Kerwin WS, Casalini JR, Thirstrup DJ, You S et al..  2015.  A technology platform to assess multiple cancer agents simultaneously within a patient's tumor.. Science translational medicine. 7(284):284ra58. Abstract

Herman JA, Toledo CM, Olson JM, DeLuca JG, Paddison PJ. Molecular pathways: regulation and targeting of kinetochore-microtubule attachment in cancer. Clin Cancer Res. 2015 Jan 15;21(2):233-9


Sipione, S, Rigamonti D, Valenza M, Zuccato C, Conti L, Pritchard J, Kooperberg C, Olson JM, Cattaneo E.  2014.  Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses.. Human molecular genetics.

Morfouace, M, Shelat A, Jacus M, Freeman BB, Turner D, Robinson S, Zindy F, Wang Y-D, Finkelstein D, Ayrault O et al..  2014.  Pemetrexed and Gemcitabine as Combination Therapy for the Treatment of Group3 Medulloblastoma.. Cancer cell. Abstract

Olson, JM.  2014.  Therapeutic opportunities for medulloblastoma come of age.. Cancer cell. 25(3):267-9. Abstract

Shih, DJH, Northcott PA, Remke M, Korshunov A, Ramaswamy V, Kool M, Luu B, Yao Y, Wang X, Dubuc AM et al..  2014.  Cytogenetic Prognostication Within Medulloblastoma Subgroups.. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. Abstract

Toledo, CM, Herman JA, Olsen JB, Ding Y, Corrin P, Girard EJ, Olson JM, Emili A, Deluca JG, Paddison PJ.  2014.  BuGZ Is Required for Bub3 Stability, Bub1 Kinetochore Function, and Chromosome Alignment.. Developmental cell. 28(3):282-94. Abstract

Kumar, A, Boyle EA, Tokita M, Mikheev AM, Sanger MC, Girard E, Silber JR, Gonzalez-Cuyar LF, Hiatt JB, Adey A et al..  2014.  Deep sequencing of multiple regions of glial tumors reveals spatial heterogeneity for mutations in clinically relevant genes.. Genome biology. 15(12):530. Abstract


Dey, J, Dubuc AM, Pedro KD, Thirstrup D, Mecham B, Northcott PA, Wu X, Shih D, Tapscott SJ, LeBlanc M et al..  2013.  MyoD Is a Tumor Suppressor Gene in Medulloblastoma.. Cancer research. Abstract

Gottardo, NG, Hansford JR, McGlade JP, Alvaro F, Ashley DM, Bailey S, Baker DL, Bourdeaut F, Cho Y-J, Clay M et al..  2013.  Medulloblastoma Down Under 2013: a report from the third annual meeting of the International Medulloblastoma Working Group.. Acta neuropathologica. Abstract

Hubert, CG, Bradley RK, Ding Y, Toledo CM, Herman J, Skutt-Kakaria K, Girard EJ, Davison J, Berndt J, Corrin P et al..  2013.  Genome-wide RNAi screens in human brain tumor isolates reveal a novel viability requirement for PHF5A.. Genes & development. 27(9):1032-45. Abstract

Aref, D, Moffatt CJ, Agnihotri S, Ramaswamy V, Dubuc AM, Northcott PA, Taylor MD, Perry A, Olson JM, Eberhart CG et al..  2013.  Canonical TGF-β Pathway Activity Is a Predictor of SHH-Driven Medulloblastoma Survival and Delineates Putative Precursors in Cerebellar Development.. Brain pathology (Zurich, Switzerland). 23(2):178-91. Abstract

Diede, SJ, Yao Z, Keyes CC, Tyler AE, Dey J, Hackett CS, Elsaesser K, Kemp CJ, Neiman PE, Weiss WA et al..  2013.  Fundamental differences in promoter CpG island DNA hypermethylation between human cancer and genetically engineered mouse models of cancer.. Epigenetics : official journal of the DNA Methylation Society. 8(12):1254-60. Abstract

Hatton, BA, Ellison DW, Gajjar A, Kool M, Fero M, Olson JM.  2013.  Prognostic value and functional consequences of cell cycle inhibitor p27Kip1 loss in medulloblastoma.. Biomarker research. 1(1):14. Abstract

Lee, SJ, Lindsey S, Graves B, Yoo S, Olson JM, Langhans SA.  2013.  Sonic hedgehog-induced histone deacetylase activation is required for cerebellar granule precursor hyperplasia in medulloblastoma.. PloS one. 8(8):e71455. Abstract













  • Hughes R.E., Lo R.S., Davis C., Strand A.D., Neal C.L., Olson J.M., Fields S. Altered transcription in yeast expressing expanded polyglutamine. Proc. Natl. Acad. Sci. USA. Nov 6;98(23):13201-6, 2001. Full Text | Abstract
  • Kiehl, T.-K., Olson, J.M., and Pulst, S.-M. The Hereditary Disease Array Group (HDAG) - Microarrays, Models and Mechanisms: A Collaboration Update. Current Genomics 2:221-229, 2001.