J. LEE NELSON LAB -- Publications

Nelson Lab Publications

2016

Stevens AM, Kanaan SB, Torok KS, Medsger TA, Mayes MD, Reveille JD, Klein-Gitelman M, Reed AM, Lee T, Li SC, Henstorf G, Luu C, Aydelotte T, Lee Nelson J. Brief Report: HLA-DRB1, DQA1, and DQB1 in Juvenile-Onset Systemic Sclerosis. Arthritis Rheumatol. 2016 Nov;68(11):2772-2777. doi: 10.1002/art.39765. PubMed PMID: 27214100.

Guthrie KA, Gammill HS, Kamper-Jørgensen M, Tjønneland A, Gadi VK, Nelson JL, Leisenring W. Statistical Methods for Unusual Count Data: Examples From Studies of Microchimerism. Am J Epidemiol. 2016 Oct 21. [Epub ahead of print] PubMed PMID: 27769989.

Kanaan SB, Onat OE, Balandraud N, Martin GV, Nelson JL, Azzouz DF, Auger I, Arnoux F, Martin M, Roudier J, Ozcelik T, Lambert NC. Evaluation of X Chromosome Inactivation with Respect to HLA Genetic Susceptibility in Rheumatoid Arthritis and Systemic Sclerosis. PLoS One. 2016 Jun 29;11(6):e0158550. doi: 10.1371/journal.pone.0158550. PubMed PMID: 27355582; PubMed Central PMCID: PMC4927113.

2015

Mittal A, Pachter L, Nelson JL, Kjærgaard H, Smed MK, Gildengorin VL, Zoffmann V, Hetland ML, Jewell NP, Olsen J, Jawaheer D. Pregnancy-Induced Changes in Systemic Gene Expression among Healthy Women and Women with Rheumatoid Arthritis.PLoS One. 2015 Dec 18;10(12):e0145204. doi: 10.1371/journal.pone.0145204. PubMed PMID: 26683605; PubMed Central PMCID: PMC4684291.

Gammill HS, Milano F, Nelson JL. Breastfeeding and Childhood Leukemia Incidence: Duplicate Data Inadvertently Included in the Meta-analysis and Consideration of Possible Confounders. JAMA Pediatr. 2015 Nov;169(11):1071. doi: 10.1001/jamapediatrics.2015.2646. Erratum in: JAMA Pediatr. 2016 Mar;170(3):299. Nelson, Lee J [corrected to Nelson, J Lee]. PubMed PMID: 26523817; PubMed Central PMCID: PMC4837330

2014

Gammill HS, Stephenson MD, Aydelotte TM, Nelson JL. Microchimerism in recurrent miscarriage. Cell Mol Immunol. 2014 Nov;11(6):589-94. doi: 10.1038/cmi.2014.82. PubMed PMID: 25242272; PubMed Central PMCID: PMC4220842.

Ma KK, Nelson JL, Guthrie KA, Dugowson CE, Gammill HS. Adverse pregnancy outcomes and risk of subsequent rheumatoid arthritis. Arthritis Rheumatol. 2014 Mar;66(3):508-12. doi: 10.1002/art.38247. PubMed PMID: 24574209.

Gammill HS, Stephenson MD, Aydelotte TM, Nelson JL. Microchimerism in women with recurrent miscarriage. Chimerism. 2014;5(3-4):103-5. doi: 10.1080/19381956.2015.1017241. Review. PubMed PMID: 25779348.

2013

Gammill HS, Aydelotte TM, Guthrie KA, Nkwopara EC, Nelson JL. Cellular fetal microchimerism in preeclampsia. Hypertension. 2013 Dec;62(6):1062-7. doi: 10.1161/HYPERTENSIONAHA.113.01486. PubMed PMID: 24101661; PubMed Central PMCID: PMC4395136.

Peterson SE, Nelson JL, Gadi VK, Gammill HS. Fetal cellular microchimerism in miscarriage and pregnancy termination.Chimerism. 2013 Oct-Dec;4(4):136-8. doi: 10.4161/chim.24915. PubMed PMID: 23723084; PubMed Central PMCID: PMC3921195.

Inamoto Y, Storer BE, Petersdorf EW, Nelson JL, Lee SJ, Carpenter PA, Sandmaier BM, Hansen JA, Martin PJ, Flowers ME. Incidence, risk factors, and outcomes of sclerosis in patients with chronic graft-versus-host disease. Blood. 2013 Jun 20;121(25):5098-103. doi: 10.1182/blood-2012-10-464198. PubMed PMID: 23547053; PubMed Central PMCID: PMC3689252.

Milano F, Nelson JL, Delaney C. Fetal maternal immunity and antileukemia activity in cord-blood transplant recipients. Bone Marrow Transplant. 2013 Mar;48(3):321-2. doi: 10.1038/bmt.2012.157. PubMed PMID: 23000655.

Mueller BA, Nelson JL, Newcomb PA. Intrauterine environment and multiple sclerosis: a population- based case-control study.Mult Scler. 2013 Jan;19(1):106-11. doi: 10.1177/1352458512447869. PubMed PMID: 22570360.

2012

Peterson SE, Nelson JL, Guthrie KA, Gadi VK, Aydelotte TM, Oyer DJ, Prager SW, Gammill HS. Prospective assessment of fetal-maternal cell transfer in miscarriage and pregnancy termination. Hum Reprod. 2012 Sep;27(9):2607-12. doi: 10.1093/humrep/des244. PubMed PMID: 22752611; PubMed Central PMCID: PMC3415291.

Nelson JL. The otherness of self: microchimerism in health and disease. Trends Immunol. 2012 Aug;33(8):421-7. doi: 10.1016/j.it.2012.03.002. Review. PubMed PMID: 22609148; PubMed Central PMCID: PMC3516290.

Chan WF, Atkins CJ, Naysmith D, van der Westhuizen N, Woo J, Nelson JL. Microchimerism in the rheumatoid nodules of patients with rheumatoid arthritis. Arthritis Rheum. 2012 Feb;64(2):380-8. doi: 10.1002/art.33358. PubMed PMID: 21953057; PubMed Central PMCID: PMC3258459.

Chan WF, Gurnot C, Montine TJ, Sonnen JA, Guthrie KA, Nelson JL. Male microchimerism in the human female brain. PLoS One. 2012;7(9):e45592. doi: 10.1371/journal.pone.0045592. PubMed PMID: 23049819; PubMed Central PMCID: PMC3458919.

2011

Gadi VK, Nelson JL, Guthrie KA, Anderson CC, Boespflug ND, Redinger JW, Paul B, Dinyari P, Shapiro AM. Soluble donor DNA and islet injury after transplantation. Transplantation. 2011 Sep 15;92(5):607-11. doi: 10.1097/TP.0b013e318228d799. PubMed PMID: 21747325.

Gorlova O, Martin JE, Rueda B, Koeleman BP, Ying J, Teruel M, Diaz-Gallo LM, Broen JC, Vonk MC, Simeon CP, Alizadeh BZ, Coenen MJ, Voskuyl AE, Schuerwegh AJ, van Riel PL, Vanthuyne M, van 't Slot R, Italiaander A, Ophoff RA, Hunzelmann N, Fonollosa V, Ortego-Centeno N, González-Gay MA, García-Hernández FJ, González-Escribano MF, Airo P, van Laar J, Worthington J, Hesselstrand R, Smith V, de Keyser F, Houssiau F, Chee MM, Madhok R, Shiels PG, Westhovens R, Kreuter A, de Baere E, Witte T, Padyukov L, Nordin A, Scorza R, Lunardi C, Lie BA, Hoffmann-Vold AM, Palm O, García de la Peña P, Carreira P; Spanish Scleroderma Group., Varga J, Hinchcliff M, Lee AT, Gourh P, Amos CI, Wigley FM, Hummers LK, Nelson JL, Riemekasten G, Herrick A, Beretta L, Fonseca C, Denton CP, Gregersen PK, Agarwal S, Assassi S, Tan FK, Arnett FC, Radstake TR, Mayes MD, Martin J. Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy. PLoS Genet. 2011 Jul;7(7):e1002178. doi: 10.1371/journal.pgen.1002178. Erratum in: PLoS Genet. 2011 Aug;7(8). doi:10.1371/annotation/3aeebb2e-64e5-4548-8d65-1f2d5dfeb073. PLoS Genet. 2011 Aug;7(8). doi:10.1371/annotation/7a52649c-0942-4bd8-a5d3-3cdacca03cd8. Hummers, J [removed]. PubMed PMID: 21779181; PubMed Central PMCID: PMC3136437.

Ostensen M, Brucato A, Carp H, Chambers C, Dolhain RJ, Doria A, Förger F, Gordon C, Hahn S, Khamashta M, Lockshin MD, Matucci-Cerinic M, Meroni P, Nelson JL, Parke A, Petri M, Raio L, Ruiz-Irastorza G, Silva CA, Tincani A, Villiger PM, Wunder D, Cutolo M. Pregnancy and reproduction in autoimmune rheumatic diseases. Rheumatology (Oxford). 2011 Apr;50(4):657-64. doi: 10.1093/rheumatology/keq350. Review. PubMed PMID: 21097449.

Yan Z, Aydelotte T, Gadi VK, Guthrie KA, Nelson JL. Acquisition of the rheumatoid arthritis HLA shared epitope through microchimerism. Arthritis Rheum. 2011 Mar;63(3):640-4. doi: 10.1002/art.30160. PubMed PMID: 21360493; PubMed Central PMCID: PMC3188444.

Gammill HS, Adams Waldorf KM, Aydelotte TM, Lucas J, Leisenring WM, Lambert NC, Nelson JL. Pregnancy, microchimerism, and the maternal grandmother. PLoS One. 2011;6(8):e24101. doi: 10.1371/journal.pone.0024101. PubMed PMID: 21912617; PubMed Central PMCID: PMC3166068.

Guthrie KA, Gammill HS, Madeleine MM, Dugowson CE, Nelson JL. Parity and HLA alleles in risk of rheumatoid arthritis.Chimerism. 2011 Jan;2(1):11-5. doi: 10.4161/chim.2.1.15424. PubMed PMID: 21547030; PubMed Central PMCID: PMC3084950.

2010

Gammill HS, Guthrie KA, Aydelotte TM, Adams Waldorf KM, Nelson JL. Effect of parity on fetal and maternal microchimerism: interaction of grafts within a host? Blood. 2010 Oct 14;116(15):2706-12. doi: 10.1182/blood-2010-02-270942. PubMed PMID: 20628146; PubMed Central PMCID: PMC2974583.

Sunku CC, Gadi VK, de Laval de Lacoste B, Guthrie KA, Nelson JL. Maternal and fetal microchimerism in granulocytes.Chimerism. 2010 Jul-Sep;1(1):11-4. doi: 10.4161/chim.1.1.13098. PubMed PMID: 21327147; PubMed Central PMCID: PMC3035109.

Adams Waldorf KM, Gammill HS, Lucas J, Aydelotte TM, Leisenring WM, Lambert NC, Nelson JL. Dynamic changes in fetal microchimerism in maternal peripheral blood mononuclear cells, CD4+ and CD8+ cells in normal pregnancy. Placenta. 2010 Jul;31(7):589-94. doi: 10.1016/j.placenta.2010.04.013. PubMed PMID: 20569981; PubMed Central PMCID: PMC2923456.

Guthrie KA, Dugowson CE, Voigt LF, Koepsell TD, Nelson JL. Does pregnancy provide vaccine-like protection against rheumatoid arthritis? Arthritis Rheum. 2010 Jul;62(7):1842-8. doi: 10.1002/art.27459. PubMed PMID: 20309863; PubMed Central PMCID: PMC2910625.

Radstake TR, Gorlova O, Rueda B, Martin JE, Alizadeh BZ, Palomino-Morales R, Coenen MJ, Vonk MC, Voskuyl AE, Schuerwegh AJ, Broen JC, van Riel PL, van 't Slot R, Italiaander A, Ophoff RA, Riemekasten G, Hunzelmann N, Simeon CP, Ortego-Centeno N, González-Gay MA, González-Escribano MF; Spanish Scleroderma Group., Airo P, van Laar J, Herrick A, Worthington J, Hesselstrand R, Smith V, de Keyser F, Houssiau F, Chee MM, Madhok R, Shiels P, Westhovens R, Kreuter A, Kiener H, de Baere E, Witte T, Padykov L, Klareskog L, Beretta L, Scorza R, Lie BA, Hoffmann-Vold AM, Carreira P, Varga J, Hinchcliff M, Gregersen PK, Lee AT, Ying J, Han Y, Weng SF, Amos CI, Wigley FM, Hummers L, Nelson JL, Agarwal SK, Assassi S, Gourh P, Tan FK, Koeleman BP, Arnett FC, Martin J, Mayes MD. Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus. Nat Genet. 2010 May;42(5):426-9. doi: 10.1038/ng.565. PubMed PMID: 20383147; PubMed Central PMCID: PMC2861917.

Gammill HS, Nelson JL. Naturally acquired microchimerism. Int J Dev Biol. 2010;54(2-3):531-43. doi: 10.1387/ijdb.082767hg. Review. PubMed PMID: 19924635; PubMed Central PMCID: PMC2887685.

2009

Rueda B, Simeon C, Hesselstrand R, Herrick A, Worthington J, Ortego-Centeno N, Riemekasten G, Fonollosa V, Vonk MC, van den Hoogen FH, Sanchez-Román J, Aguirre-Zamorano MA, García-Portales R, Pros A, Camps MT, Gonzalez-Gay MA, Gonzalez-Escribano MF, Coenen MJ, Lambert N, Nelson JL, Radstake TR, Martin J. A large multicentre analysis of CTGF -945 promoter polymorphism does not confirm association with systemic sclerosis susceptibility or phenotype. Ann Rheum Dis. 2009 Oct;68(10):1618-20. doi: 10.1136/ard.2008.100180. PubMed PMID: 19054816; PubMed Central PMCID: PMC2743760.

Stevens AM, Hermes HM, Kiefer MM, Rutledge JC, Nelson JL. Chimeric maternal cells with tissue-specific antigen expression and morphology are common in infant tissues. Pediatr Dev Pathol. 2009 Sep-Oct;12(5):337-46. doi: 10.2350/08-07-0499.1. PubMed PMID: 18939886; PubMed Central PMCID: PMC2783488.

Rueda B, Broen J, Simeon C, Hesselstrand R, Diaz B, Suárez H, Ortego-Centeno N, Riemekasten G, Fonollosa V, Vonk MC, van den Hoogen FH, Sanchez-Román J, Aguirre-Zamorano MA, García-Portales R, Pros A, Camps MT, Gonzalez-Gay MA, Coenen MJ, Airo P, Beretta L, Scorza R, van Laar J, Gonzalez-Escribano MF, Nelson JL, Radstake TR, Martin J. The STAT4 gene influences the genetic predisposition to systemic sclerosis phenotype. Hum Mol Genet. 2009 Jun 1;18(11):2071-7. doi: 10.1093/hmg/ddp119. PubMed PMID: 19286670.

Guthrie KA, Tishkevich NR, Nelson JL. Non-inherited maternal human leukocyte antigen alleles in susceptibility to familial rheumatoid arthritis. Ann Rheum Dis. 2009 Jan;68(1):107-9. doi: 10.1136/ard.2008.092312. PubMed PMID: 18684745; PubMed Central PMCID: PMC2760537.

Nelson JL. Naturally acquired microchimerism: for better or for worse. Arthritis Rheum. 2009 Jan;60(1):5-7. doi: 10.1002/art.24217. PubMed PMID: 19116911; PubMed Central PMCID: PMC2693961.

2008

Uz E, Loubiere LS, Gadi VK, Ozbalkan Z, Stewart J, Nelson JL, Ozcelik T. Skewed X-chromosome inactivation in scleroderma.Clin Rev Allergy Immunol. 2008 Jun;34(3):352-5. PubMed PMID: 18157513; PubMed Central PMCID: PMC2716291.

Gadi VK, Malone KE, Guthrie KA, Porter PL, Nelson JL. Case-control study of fetal microchimerism and breast cancer. PLoS One. 2008 Mar 5;3(3):e1706. doi: 10.1371/journal.pone.0001706. PubMed PMID: 18320027; PubMed Central PMCID: PMC2248618.

Nelson JL. Your cells are my cells. Sci Am. 2008 Feb;298(2):64-71. PubMed PMID: 18376674.

Adams Waldorf KM, Nelson JL. Autoimmune disease during pregnancy and the microchimerism legacy of pregnancy. Immunol Invest. 2008;37(5):631-44. doi: 10.1080/08820130802205886. PubMed PMID: 18716941; PubMed Central PMCID: PMC2709983.

2007

Yan Z, Ferucci ED, Geraghty DE, Yang Y, Lanier AP, Smith WP, Zhao LP, Hansen JA, Nelson JL. Resequencing of the human major histocompatibility complex in patients with rheumatoid arthritis and healthy controls in Alaska Natives of Southeast Alaska.Tissue Antigens. 2007 Dec;70(6):487-94. PubMed PMID: 17990987.

Gadi VK, Nelson JL. Fetal microchimerism in women with breast cancer. Cancer Res. 2007 Oct 1;67(19):9035-8. PubMed PMID: 17909006.

Nash RA, McSweeney PA, Crofford LJ, Abidi M, Chen CS, Godwin JD, Gooley TA, Holmberg L, Henstorf G, LeMaistre CF, Mayes MD, McDonagh KT, McLaughlin B, Molitor JA, Nelson JL, Shulman H, Storb R, Viganego F, Wener MH, Seibold JR, Sullivan KM, Furst DE. High-dose immunosuppressive therapy and autologous hematopoietic cell transplantation for severe systemic sclerosis: long-term follow-up of the US multicenter pilot study. Blood. 2007 Aug 15;110(4):1388-96. PubMed PMID: 17452515; PubMed Central PMCID: PMC1939909.

Adams KM, Yan Z, Stevens AM, Nelson JL. The changing maternal "self" hypothesis: a mechanism for maternal tolerance of the fetus. Placenta. 2007 May-Jun;28(5-6):378-82. PubMed PMID: 16934327.

Nelson JL, Gillespie KM, Lambert NC, Stevens AM, Loubiere LS, Rutledge JC, Leisenring WM, Erickson TD, Yan Z, Mullarkey ME, Boespflug ND, Bingley PJ, Gale EA. Maternal microchimerism in peripheral blood in type 1 diabetes and pancreatic islet beta cell microchimerism. Proc Natl Acad Sci U S A. 2007 Jan 30;104(5):1637-42. PubMed PMID: 17244711; PubMed Central PMCID: PMC1785262.

2006

Loubière LS, Lambert NC, Flinn LJ, Erickson TD, Yan Z, Guthrie KA, Vickers KT, Nelson JL. Maternal microchimerism in healthy adults in lymphocytes, monocyte/macrophages and NK cells. Lab Invest. 2006 Nov;86(11):1185-92. PubMed PMID: 16969370.

Yan Z, Lambert NC, Ostensen M, Adams KM, Guthrie KA, Nelson JL. Prospective study of fetal DNA in serum and disease activity during pregnancy in women with inflammatory arthritis. Arthritis Rheum. 2006 Jul;54(7):2069-73. PubMed PMID: 16804866.

Nash RA, McSweeney PA, Nelson JL, Wener M, Georges GE, Langston AA, Shulman H, Sullivan KM, Lee J, Henstorf G, Storb R, Furst DE. Allogeneic marrow transplantation in patients with severe systemic sclerosis: resolution of dermal fibrosis. Arthritis Rheum. 2006 Jun;54(6):1982-6. PubMed PMID: 16732546; PubMed Central PMCID: PMC2956579.

Gadi VK, Nelson JL, Boespflug ND, Guthrie KA, Kuhr CS. Soluble donor DNA concentrations in recipient serum correlate with pancreas-kidney rejection. Clin Chem. 2006 Mar;52(3):379-82. PubMed PMID: 16397013.

2005

Schiff MA, Apple RJ, Lin P, Nelson JL, Wheeler CM, Becker TM. HLA alleles and risk of cervical intraepithelial neoplasia among southwestern American Indian women. Hum Immunol. 2005 Oct;66(10):1050-6. PubMed PMID: 16386646.

Stevens AM, Tsao BP, Hahn BH, Guthrie K, Lambert NC, Porter AJ, Tylee TS, Nelson JL. Maternal HLA class II compatibility in men with systemic lupus erythematosus. Arthritis Rheum. 2005 Sep;52(9):2768-73. Erratum in: Arthritis Rheum. 2006 Jan;54(1):355. PubMed PMID: 16142706.

Yan Z, Lambert NC, Guthrie KA, Porter AJ, Loubiere LS, Madeleine MM, Stevens AM, Hermes HM, Nelson JL. Male microchimerism in women without sons: quantitative assessment and correlation with pregnancy history. Am J Med. 2005 Aug;118(8):899-906. PubMed PMID: 16084184.

Lambert NC, Pang JM, Yan Z, Erickson TD, Stevens AM, Furst DE, Nelson JL. Male microchimerism in women with systemic sclerosis and healthy women who have never given birth to a son. Ann Rheum Dis. 2005 Jun;64(6):845-8. PubMed PMID: 15550532; PubMed Central PMCID: PMC1755528.

Østensen M, Förger F, Nelson JL, Schuhmacher A, Hebisch G, Villiger PM. Pregnancy in patients with rheumatic disease: anti-inflammatory cytokines increase in pregnancy and decrease post partum. Ann Rheum Dis. 2005 Jun;64(6):839-44. PubMed PMID: 15539410; PubMed Central PMCID: PMC1755520.

Lucas KG, Nelson JL, Erickson TD, Sun Q. Microchimerism detection by human leucocyte antigen-specific quantitative-polymerase chain reaction analysis in recipients of allogeneic Epstein-Barr virus-specific cytotoxic T lymphocytes. Br J Haematol. 2005 May;129(3):443-4. PubMed PMID: 15842671.

Loubière LS, Lambert NC, Madeleine MM, Porter AJ, Mullarkey ME, Pang JM, Galloway DA, Furst DE, Nelson JL. HLA allelic variants encoding DR11 in diffuse and limited systemic sclerosis in Caucasian women. Rheumatology (Oxford). 2005 Mar;44(3):318-22. Erratum in: Rheumatology (Oxford). 2005 Apr;44(4):569. PubMed PMID: 15572392.

Mullarkey ME, Stevens AM, McDonnell WM, Loubière LS, Brackensick JA, Pang JM, Porter AJ, Galloway DA, Nelson JL. Human leukocyte antigen class II alleles in Caucasian women with primary biliary cirrhosis. Tissue Antigens. 2005 Feb;65(2):199-205. PubMed PMID: 15713222.

Stevens AM, Hermes HM, Lambert NC, Nelson JL, Meroni PL, Cimaz R. Maternal and sibling microchimerism in twins and triplets discordant for neonatal lupus syndrome-congenital heart block. Rheumatology (Oxford). 2005 Feb;44(2):187-91. PubMed PMID: 15536065.

2004

Stevens AM, McDonnell WM, Mullarkey ME, Pang JM, Leisenring W, Nelson JL. Liver biopsies from human females contain male hepatocytes in the absence of transplantation. Lab Invest. 2004 Dec;84(12):1603-9. PubMed PMID: 15502859.

Adams KM, Holmberg LA, Leisenring W, Fefer A, Guthrie KA, Tylee TS, McDonald GB, Bensinger WI, Nelson JL. Risk factors for syngeneic graft-versus-host disease after adult hematopoietic cell transplantation. Blood. 2004 Sep 15;104(6):1894-7. PubMed PMID: 15117763.

Adams KM, Nelson JL. Microchimerism: an investigative frontier in autoimmunity and transplantation. JAMA. 2004 Mar 3;291(9):1127-31. Review. PubMed PMID: 14996783.

Lambert NC, Erickson TD, Yan Z, Pang JM, Guthrie KA, Furst DE, Nelson JL. Quantification of maternal microchimerism by HLA-specific real-time polymerase chain reaction: studies of healthy women and women with scleroderma. Arthritis Rheum. 2004 Mar;50(3):906-14. PubMed PMID: 15022334.

2003

Stevens AM, Hermes HM, Rutledge JC, Buyon JP, Nelson JL. Myocardial-tissue-specific phenotype of maternal microchimerism in neonatal lupus congenital heart block. Lancet. 2003 Nov 15;362(9396):1617-23. PubMed PMID: 14630442.

Adams KM, Lambert NC, Heimfeld S, Tylee TS, Pang JM, Erickson TD, Nelson JL. Male DNA in female donor apheresis and CD34-enriched products. Blood. 2003 Nov 15;102(10):3845-7. PubMed PMID: 12869496.

Groh V, Bruhl A, El-Gabalawy H, Nelson JL, Spies T. Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid arthritis. Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9452-7. PubMed PMID: 12878725; PubMed Central PMCID: PMC170939.

Lambert N, Nelson JL. Microchimerism in autoimmune disease: more questions than answers? Autoimmun Rev. 2003 May;2(3):133-9. Review. PubMed PMID: 12848954.

Jawaheer D, Seldin MF, Amos CI, Chen WV, Shigeta R, Etzel C, Damle A, Xiao X, Chen D, Lum RF, Monteiro J, Kern M, Criswell LA, Albani S, Nelson JL, Clegg DO, Pope R, Schroeder HW Jr, Bridges SL Jr, Pisetsky DS, Ward R, Kastner DL, Wilder RL, Pincus T, Callahan LF, Flemming D, Wener MH, Gregersen PK; North American Rheumatoid Arthritis Consortium.. Screening the genome for rheumatoid arthritis susceptibility genes: a replication study and combined analysis of 512 multicase families.Arthritis Rheum. 2003 Apr;48(4):906-16. PubMed PMID: 12687532.

Nelson JL. Microchimerism in human health and disease. Autoimmunity. 2003 Feb;36(1):5-9. Review. PubMed PMID: 12765465.

2002

Madeleine MM, Brumback B, Cushing-Haugen KL, Schwartz SM, Daling JR, Smith AG, Nelson JL, Porter P, Shera KA, McDougall JK, Galloway DA. Human leukocyte antigen class II and cervical cancer risk: a population-based study. J Infect Dis. 2002 Dec 1;186(11):1565-74. PubMed PMID: 12447731.

Johnson KL, Samura O, Nelson JL, McDonnell M d WM, Bianchi DW. Significant fetal cell microchimerism in a nontransfused woman with hepatitis C: Evidence of long-term survival and expansion. Hepatology. 2002 Nov;36(5):1295-7. PubMed PMID: 12395344.

Lambert NC, Lo YM, Erickson TD, Tylee TS, Guthrie KA, Furst DE, Nelson JL. Male microchimerism in healthy women and women with scleroderma: cells or circulating DNA? A quantitative answer. Blood. 2002 Oct 15;100(8):2845-51. PubMed PMID: 12351394.

McSweeney PA, Nash RA, Sullivan KM, Storek J, Crofford LJ, Dansey R, Mayes MD, McDonagh KT, Nelson JL, Gooley TA, Holmberg LA, Chen CS, Wener MH, Ryan K, Sunderhaus J, Russell K, Rambharose J, Storb R, Furst DE. High-dose immunosuppressive therapy for severe systemic sclerosis: initial outcomes. Blood. 2002 Sep 1;100(5):1602-10. PubMed PMID: 12176878; PubMed Central PMCID: PMC2956742.

Stevens AM, McDonnell WM, Nelson JL. Male cells in female recipients of hematopoietic-cell transplants. N Engl J Med. 2002 Jul 18;347(3):218-20; author reply 218-20. PubMed PMID: 12125712.

Nelson JL. Microchimerism: incidental byproduct of pregnancy or active participant in human health? Trends Mol Med. 2002 Mar;8(3):109-13. PubMed PMID: 11879770.

Nelson JL. Pregnancy and microchimerism in autoimmune disease: protector or insurgent? Arthritis Rheum. 2002 Feb;46(2):291-7. Review. PubMed PMID: 11840431.

2001

Johnson KL, Nelson JL, Furst DE, McSweeney PA, Roberts DJ, Zhen DK, Bianchi DW. Fetal cell microchimerism in tissue from multiple sites in women with systemic sclerosis. Arthritis Rheum. 2001 Aug;44(8):1848-54. PubMed PMID: 11508438.

Jawaheer D, Seldin MF, Amos CI, Chen WV, Shigeta R, Monteiro J, Kern M, Criswell LA, Albani S, Nelson JL, Clegg DO, Pope R, Schroeder HW Jr, Bridges SL Jr, Pisetsky DS, Ward R, Kastner DL, Wilder RL, Pincus T, Callahan LF, Flemming D, Wener MH, Gregersen PK. A genomewide screen in multiplex rheumatoid arthritis families suggests genetic overlap with other autoimmune diseases. Am J Hum Genet. 2001 Apr;68(4):927-36. PubMed PMID: 11254450; PubMed Central PMCID: PMC1275647.

2000

Lambert NC, Distler O, Müller-Ladner U, Tylee TS, Furst DE, Nelson JL. HLA-DQA1*0501 is associated with diffuse systemic sclerosis in Caucasian men. Arthritis Rheum. 2000 Sep;43(9):2005-10. PubMed PMID: 11014350.

Lambert NC, Evans PC, Hashizumi TL, Maloney S, Gooley T, Furst DE, Nelson JL. Cutting edge: persistent fetal microchimerism in T lymphocytes is associated with HLA-DQA1*0501: implications in autoimmunity. J Immunol. 2000 Jun 1;164(11):5545-8. PubMed PMID: 10820227.

Richards MH, Nelson JL. The evolution of vertebrate antigen receptors: a phylogenetic approach. Mol Biol Evol. 2000 Jan;17(1):146-55. PubMed PMID: 10666714.

Nelson JL. Rheumatoid arthritis remission/relapse and the Health Assessment Questionnaire: comment on the article by Barrett et al. Arthritis Rheum. 2000 Jan;43(1):234. PubMed PMID: 10643721.

1999

Tanaka A, Lindor K, Gish R, Batts K, Shiratori Y, Omata M, Nelson JL, Ansari A, Coppel R, Newsome M, Gershwin ME. Fetal microchimerism alone does not contribute to the induction of primary biliary cirrhosis. Hepatology. 1999 Oct;30(4):833-8. PubMed PMID: 10498630.

Maloney S, Smith A, Furst DE, Myerson D, Rupert K, Evans PC, Nelson JL. Microchimerism of maternal origin persists into adult life. J Clin Invest. 1999 Jul;104(1):41-7. PubMed PMID: 10393697; PubMed Central PMCID: PMC408407.

Evans PC, Lambert N, Maloney S, Furst DE, Moore JM, Nelson JL. Long-term fetal microchimerism in peripheral blood mononuclear cell subsets in healthy women and women with scleroderma. Blood. 1999 Mar 15;93(6):2033-7. PubMed PMID: 10068676.

1998

Nelson JL. Pregnancy immunology and autoimmune disease. J Reprod Med. 1998 Apr;43(4):335-40. Review. PubMed PMID: 9583065.

Nelson JL, Furst DE, Maloney S, Gooley T, Evans PC, Smith A, Bean MA, Ober C, Bianchi DW. Microchimerism and HLA-compatible relationships of pregnancy in scleroderma. Lancet. 1998 Feb 21;351(9102):559-62. PubMed PMID: 9492775.

1997

La Cava A, Nelson JL, Ollier WE, MacGregor A, Keystone EC, Thorne JC, Scavulli JF, Berry CC, Carson DA, Albani S. Genetic bias in immune responses to a cassette shared by different microorganisms in patients with rheumatoid arthritis. J Clin Invest. 1997 Aug 1;100(3):658-63. PubMed PMID: 9239413; PubMed Central PMCID: PMC508234.

Nash RA, McSweeney PA, Storb R, Nelson JL, Gauthier J, Furst DE, Sullivan KM. Development of a protocol for allogeneic marrow transplantation for severe systemic sclerosis: paradigm for autoimmune disease. J Rheumatol Suppl. 1997 May;48:72-8. Review. PubMed PMID: 9150123.

Nelson JL, Torrez R, Louie FM, Choe OS, Storb R, Sullivan KM. Pre-existing autoimmune disease in patients with long-term survival after allogeneic bone marrow transplantation. J Rheumatol Suppl. 1997 May;48:23-9. PubMed PMID: 9150114.

Nelson JL, Ostensen M. Pregnancy and rheumatoid arthritis. Rheum Dis Clin North Am. 1997 Feb;23(1):195-212. Review. PubMed PMID: 9031383.

1996

Smith AG, Nelson JL, Regen L, Guthrie LA, Donadi E, Mickelson EM, Hansen JA. Six new DR52-associated DRB1 alleles, three of DR8, two of DR11, and one of DR6, reflect a variety of mechanisms which generate polymorphism in the MHC. Tissue Antigens. 1996 Aug;48(2):118-26. PubMed PMID: 8883301.

Shapiro JA, Koepsell TD, Voigt LF, Dugowson CE, Kestin M, Nelson JL. Diet and rheumatoid arthritis in women: a possible protective effect of fish consumption. Epidemiology. 1996 May;7(3):256-63. PubMed PMID: 8728438.

Nelson JL. Maternal-fetal immunology and autoimmune disease: is some autoimmune disease auto-alloimmune or allo-autoimmune? Arthritis Rheum. 1996 Feb;39(2):191-4. PubMed PMID: 8849367.

1995

Albani S, Keystone EC, Nelson JL, Ollier WE, La Cava A, Montemayor AC, Weber DA, Montecucco C, Martini A, Carson DA. Positive selection in autoimmunity: abnormal immune responses to a bacterial dnaJ antigenic determinant in patients with early rheumatoid arthritis. Nat Med. 1995 May;1(5):448-52. PubMed PMID: 7585093.

Ostensen M, Nelson JL. Bits and pieces in a puzzle--rheumatoid arthritis and pregnancy. Br J Rheumatol. 1995 Jan;34(1):1-3. PubMed PMID: 7881831.

1994

Koepsell TD, Dugowson CE, Nelson JL, Voigt LF, Daling JR. Non-contraceptive hormones and the risk of rheumatoid arthritis in menopausal women. Int J Epidemiol. 1994 Dec;23(6):1248-55. PubMed PMID: 7721528.

Voigt LF, Koepsell TD, Nelson JL, Dugowson CE, Daling JR. Smoking, obesity, alcohol consumption, and the risk of rheumatoid arthritis. Epidemiology. 1994 Sep;5(5):525-32. PubMed PMID: 7986867.

Templin DW, Boyer GS, Lanier AP, Nelson JL, Barrington RA, Hansen JA, Harpster A, Carlsen R. Rheumatoid arthritis in Tlingit Indians: clinical characterization and HLA associations. J Rheumatol. 1994 Jul;21(7):1238-44. PubMed PMID: 7525956.

Nelson JL, Dugowson CE, Koepsell TD, Voigt LF, Branchaud AM, Barrington RA, Wener MH, Hansen JA. Rheumatoid factor, HLA-DR4, and allelic variants of DRB1 in women with recent-onset rheumatoid arthritis. Arthritis Rheum. 1994 May;37(5):673-80. PubMed PMID: 8185694.

Charmley P, Nelson JL, Hansen JA, Branchaud A, Barrington RA, Templin D, Boyer G, Lanier AP, Concannon P. T-cell receptor polymorphisms in Tlingit Indians with rheumatoid arthritis. Autoimmunity. 1994;19(4):247-51. PubMed PMID: 7578851.

1993

Nelson JL, Hughes KA, Smith AG, Nisperos BB, Branchaud AM, Hansen JA. Maternal-fetal disparity in HLA class II alloantigens and the pregnancy-induced amelioration of rheumatoid arthritis. N Engl J Med. 1993 Aug 12;329(7):466-71. PubMed PMID: 8332151.

Nelson JL, Koepsell TD, Dugowson CE, Voigt LF, Daling JR, Hansen JA. Fecundity before disease onset in women with rheumatoid arthritis. Arthritis Rheum. 1993 Jan;36(1):7-14. PubMed PMID: 8424839.

1992

Nelson JL, Hughes KA, Smith AG, Nisperos BB, Branchaud AM, Hansen JA. Remission of rheumatoid arthritis during pregnancy and maternal-fetal class II alloantigen disparity. Am J Reprod Immunol. 1992 Oct-Dec;28(3-4):226-7. PubMed PMID: 1285885.

Nelson JL, Boyer G, Templin D, Lanier A, Barrington R, Nisperos B, Smith A, Mickelson E, Hansen JA. HLA antigens in Tlingit Indians with rheumatoid arthritis. Tissue Antigens. 1992 Aug;40(2):57-63. PubMed PMID: 1412417.

Nelson JL, Voigt LF, Koepsell TD, Dugowson CE, Daling JR. Pregnancy outcome in women with rheumatoid arthritis before disease onset. J Rheumatol. 1992 Jan;19(1):18-21. PubMed PMID: 1556688.

1991

Dugowson CE, Koepsell TD, Voigt LF, Bley L, Nelson JL, Daling JR. Rheumatoid arthritis in women. Incidence rates in group health cooperative, Seattle, Washington, 1987-1989. Arthritis Rheum. 1991 Dec;34(12):1502-7. PubMed PMID: 1747134.

Nelson JL, Mickelson E, Masewicz S, Barrington R, Dugowson C, Koepsell T, Hansen JA. Dw14(DRB1*0404) is a Dw4-dependent risk factor for rheumatoid arthritis. Rethinking the "shared epitope" hypothesis. Tissue Antigens. 1991 Oct;38(4):145-51. PubMed PMID: 1724805.

1987

Nelson JL, Nardella FA, Oppliger IR, Mannik M. Rheumatoid factors from patients with rheumatoid arthritis possess private repertoires of idiotypes. J Immunol. 1987 Mar 1;138(5):1391-6. PubMed PMID: 3492550.

1985

Farmer SG, Kinyoun JL, Nelson JL, Wener MH. Retinal vasculitis associated with autoantibodies to Sjögren's syndrome A antigen. Am J Ophthalmol. 1985 Dec 15;100(6):814-21. PubMed PMID: 4073179.

Nelson JL, Nardella FA, Mannik M. Competition between antigen and anti-idiotypes for rheumatoid factors. J Immunol. 1985 Oct;135(4):2357-61. PubMed PMID: 4031493.
 

Editorials, Commentaries, Meeting Reports

van Halteren AG, Sedlmayr P, Kroneis T, Burlingham WJ, Nelson JL.  Meeting report of the first symposium on chimerism.  Chimerism 4(4):132-135, 2013. PMCID: PMC3921194

Peterson SE, Nelson JL, Gadi VK, Gammill HS.  Fetal cellular microchimerism in miscarriage and pregnancy termination. Chimerism 4(4): 136-138, 2013. PMCID: PMC3921195

Chan WF, Nelson JL.  Microchimerism in the human brain: more questions than answers.  Chimerism 4(1):32-3, 2013. PMCID: PMC3654737

Milano F, Nelson JL, Delaney C.  Fetal maternal immunity and antileukemia activity in cord-blood transplant recipients. Bone Marrow Transplant 48(3):321-2. 2013.

Burlingham WJ, Nelson JL.  Microchimerism in cord blood: mother as anti-cancer drug? Proc Natl Acad Sci USA 109(7):2190-1, 2012. PMCID: PMC3289348

Nelson JL. Naturally acquired microchimerism: For better or for worse.  Arthritis Rheum 60(1):5-7, 2009. PMCID: PMC2693961.

Nelson JL.  Your cells are my cells.  Scientific American 298(2):72-76, 2008. PMCID: PMC2693961.

Nelson JL.  Pregnancy and microchimerism in autoimmune disease: protector or insurgent? Arthritis Rheum  46:291-297, 2002.

Nelson JL. Microchimerism: expanding new horizon in human health or incidental remnant of pregnancy?  Lancet 358:2011-2, 2001.

Nelson JL.  Dunlop-Dotteridge Lecture 2000.  The Dunlop-Dottridge Lecture. Long-term persistence of fetal and maternal cells:  Implications for systemic sclerosis and other autoimmune diseases.  J Rheumatol, 27:2922-6, 2000.

Nelson JL.  Autoimmune disease and the long-term persistence of fetal and maternal microchimerism.  Lupus 8:493-6, 1999.

Nelson JL.  Non-host cells in the pathogenesis of autoimmune disease, a new paradigm?  Ann Rheum Dis 58:518-20, 1999 PMCID: PMC1752949

Nelson JL.  Microchimerism and autoimmune disease.  N Engl J Med 338:1224-5, 1998

Østensen M, Nelson JL. Bits and pieces in a puzzle - rheumatoid arthritis and pregnancyBr J Rheumatol 34:1-3, 1995.
 

Letters to the Editor

Gammill HS, Milano F, Nelson JL. Comment on: Breastfeeding and childhood leukemia incidence: duplicate data inadvertently included in the meta-analysis and consideration of possible confounders.  JAMA Pediatr 169(11):1071, 2015. PMCID: PMC4837330

Johnson KL, Samura O, Nelson JL, McDonnell WM, Bianchi DW.  Significant fetal cell microchimerism in a non-transfused woman with hepatitis C: Evidence of long-term survival and expansion.  Hepatol 36:1295-7, 2002. 

Stevens AM, McDonnell M,  Nelson JL. Comment on the report by Korbling, et al.  N Engl J Med 347:218, 2002.

Nelson JL.  Rheumatoid arthritis remission/relapse and the Health Assessment Questionnaire: comment on the article by Barrett et al.  Arthritis Rheum 43:234, 2000.
 

Books and Monographs

Adams KM, Nelson JL, Branch DW.  Autoimmune Disorders.  In: Stenchever M (ed). Clinical Updates in Women’s Health Care.  Washington, DC.  The American College of Obstetricians and Gynecologists, vol. V (no. 3), 2006.

Morrow J, Nelson JL, Watts R, Isenberg DA (eds). Autoimmune Rheumatic Diseases. 2nd edition. Oxford Unversity Press, Oxford, UK, 1999.
 

Book Chapters

Gammill HS, Peterson SE, Nelson JL.  Maternal-fetal cell trafficking and microchimerism.  In: The Placenta from development to disease.  Kay HH, Nelson DM, Wang Y (eds) Wiley-Blackwell 2011 pp81-86.

Porter, A, Nelson JL.  Immunogenetics of rheumatoid arthritis, systemic sclerosis and systemic lupus erythematosus.  In: Immunogenetics of Autoimmune Disease, Oksenberg J, Brassat D (eds).  Landes Bioscience/Eurekah.com, Springer Science and Business Media, LLC, 2006 pp75-91.

Adams KM, Nelson JL.  Bi-directional cell trafficking of pregnancy: long-term consequences for human health  In: Mor G (ed)  Immunology of pregnancy. Georgetown, Tx, Landes Biosciences. http://www.eurekah.com/book/911, 2006. 

Østensen, M, Nelson JL.  Pregnancy (in rheumatoid arthritis), p496. In: Rheumatoid Arthritis.  St Clair EW, Pisetsky DS, St. Clair EW Haynes BF (eds).  Philadelphia: Lippincott Williams & Wilkins, 2004.

Nelson JL. Rheumatoid Arthritis. Lee R, Rosene-Montella K, Barbour L, Garner P, Keely E (eds)  In: Medical Care of the Pregnant Patient.  American College of Physicians, p531-40, 2000.

Nelson JL.  Autoimmune Disease in Pregnancy: Relationships with HLA.  In: HLA and the Maternal-Fetal Relationship.  Hunt JS (ed).  R. G. Landes Co, p157-88, 1996.

Nelson JL, Steinberg AD. Sex Steroids, autoimmunity, and autoimmune diseases.  In: Hormones and Immunity.  Berczi I, Kovacs K (eds). Chapter 6 p 93-119, MTP Press Limited, Lancaster, U,

Nelson JL, Østensen ME. Rheumatoid arthritis and other arthropathies during pregnancy. In: Asthma and Immunologic Diseases in Pregnancy in Early Infancy. Schatz M, Zeiger R, Claman H, (eds) Marcel Dekker, Inc., p523-50, 1998.